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☆ New weight loss drugs trending with billionaires and celebrities are about to enter more American homes
▼ + stars: | 2023-01-20 | by ( Barbara Collins | ) www.cnbc.com time to read: +8 min

GLP-1s also have been found to help with weight loss as they make individuals who use them feel fuller for a longer period of time. Using GLP-1s drug injections for weight loss has become one of the latest ways some big names in the market are shedding extra pounds. That's why his company has launched a program to offer GLP-1 drugs and corresponding medical care to individuals struggling with obesity or weight loss issues. Pairing personalized coaching with GLP-1s is the key to effective weight loss treatment, Reitano said, and helping patients maximize their results. A new real-time approach to weight managementReitano said it should not be an either/or scenario involving diabetes management of weight loss and that will change over the next decade.

☆ What happens when you stop taking a weight loss drug? Many people gain the weight back.
▼ + stars: | 2023-01-19 | by ( Https | Media-Cldnry.S-Nbcnews.Com Image Upload Newscms Berkeley-Lovelace-Jr.Jpg | Berkeley Lovelace Jr. | ) www.nbcnews.com time to read: +4 min

She didn't find success until her doctor prescribed Wegovy, a weight loss drug, in August 2021. But it all stopped in February, when Bayandor's health insurance denied her coverage, forcing her to stop taking the medication. Artemis BayandorBayandor's experience isn't uncommon: Widespread shortages of Wegovy, a popular weight loss aid, have forced some people in the U.S. to stop taking it, leading them to gain some — or all — of their weight back. "When you're at that max weight loss, your body's hunger hormones are the highest," she said. In May, an unrelated thyroid issue landed her in the hospital and forced her to stop taking Wegovy.

☆ I prescribe the popular weight-loss drug semaglutide to my patients. I hesitate to call it a magic bullet.
▼ + stars: | 2023-01-18 | by ( Hannah Moseley | ) www.businessinsider.com time to read: +7 min

Dr. Paul Kolodzik has been prescribing semaglutide to his diabetic patients since 2017. The one regret he hears from patients on the drug is they can't enjoy food as much. Before that, I was an emergency physician for about 25 years, caring for patients with strokes, heart attacks, and diabetic emergencies. I started prescribing semaglutide under the label Ozempic to my diabetic patients in 2017Novo Nordisk, a global pharmaceutical company, developed Ozempic as a medication for diabetics to control their blood sugar. So, physicians started prescribing some patients who weren't diabetic Ozempic off-label since Ozempic is not approved for weight loss — even though it's the same generic medicine.

☆ People with diabetes struggle to find Ozempic as it soars in popularity as a weight loss aid
▼ + stars: | 2023-01-12 | by ( Https | Media-Cldnry.S-Nbcnews.Com Image Upload Newscms Berkeley-Lovelace-Jr.Jpg | Berkeley Lovelace Jr. | ) www.nbcnews.com time to read: +5 min

For the past two years, she's managed the condition using a drug called Ozempic, which helps people with diabetes keep blood sugar levels in check. "It's been very frustrating," Largent-Phillips, of Florida, said of the shortage, adding that her blood sugar levels have been fluctuating as she's had to change medications. If the body doesn't use it well, that sugar stays in the blood, resulting in high blood sugar levels. His wife, Gerilynn, who is a nurse, said his blood sugar levels have gone back up since being off Ozempic. Largent-Phillips, of Florida — who has been documenting her experience on TikTok — said that for now, she has to be vigilant about monitoring her blood sugar levels.

☆ U.S. experts recommend weight-loss drugs for obese children
▼ + stars: | 2023-01-09 | by ( Bhanvi Satija | ) www.reuters.com time to read: +4 min

Metformin has been used off label to achieve weight loss in children. Of the 27 randomized trials of metformin for weight loss in children reviewed by the guidelines panel, 74% showed some positive effect of the medication. Wegovy last month won U.S. approval for chronic weight management in children ages 12 and older. For children ages 2 to 12 years, AAP said there was not currently enough evidence to recommend use of these medications. They also include recommendations for diagnosing obesity annually in children ages 6 years and older, through checks on BMI, and practices such as motivational interviewing.

☆ Amgen says experimental obesity drug has promising durability
▼ + stars: | 2022-12-03 | by ( Deena Beasley | ) www.reuters.com time to read: +3 min

LOS ANGELES, Dec 3 (Reuters) - Amgen Inc's (AMGN.O) experimental obesity drug demonstrated promising durability trends in an early trial, paving the way for a larger mid-stage study early next year, company officials said ahead of a data presentation on Saturday. The small Phase I trial found that patients maintained their weight loss for 70 days after receiving the highest tested dose of the injected drug, currently known as AMG133. Amgen shares have gained about 5% since the company said on Nov. 7 that 12 weeks of trial treatment at the highest monthly dose of AMG133 resulted in mean weight loss of 14.5%. Patients treated with AMG133 did have side effects including nausea and vomiting, but most cases were mild and resolved within a couple of days after the first dose, Amgen said. The drug was developed from work at Amgen to identify genetic signals associated with lower fat mass and body weight, and also healthy metabolic profiles, explained Saptarsi Haldar, head of cardiovascular metabolic discovery at Amgen.

☆ If Ozempic Is in Short Supply, How Are People Getting It for Weight Loss?
▼ + stars: | 2022-12-02 | by ( Sara Ashley O'Brien | ) www.wsj.com time to read: 1 min

Jessie Cheung’s cosmetic dermatology practices in Chicago and New York City offer a range of aesthetic and wellness treatments, including Botox, fillers and a procedure known as anal rejuvenation. Recently, she said, her patients have been asking for Ozempic to help them lose weight. Though Dr. Cheung doesn’t carry the brand-name drug, her offices are stocked with syringes filled with a cheaper, custom-made version of semaglutide, Ozempic’s active ingredient, created by a drug compounder.

☆ What Is Ozempic and Why Is It Getting So Much Attention?
▼ + stars: | 2022-11-22 | by ( Dani Blum | More About Dani Blum | ) www.nytimes.com time to read: +2 min

Ozempic, a drug used to treat diabetes, keeps gaining attention as celebrities, a tech mogul and TikTok influencers have described taking it to lose weight in short time frames. Elon Musk, when asked about how he looked “fit, ripped and healthy,” tweeted that he was taking Wegovy. On TikTok, the hashtag #Ozempic has been viewed over 273 million times, with people alternately expressing shock over their supposed medication-induced weight loss and swapping stories about side effects. Ozempic and Wegovy are not the only medications gaining popularity for their weight loss effects. Dr. Narang herself has seen patients “who have somehow gotten their hands on this,” taking the medication off-label, she said.

Persons: TikTok, Elon Musk, ”, Andy Cohen, “, Ozempic, Eli Lilly, Disha, Narang Organizations: Drug Administration, Variety, Northwestern Medicine Lake Forest Hospital, Novo Nordisk Locations: Britain, Northwestern, Ozempic

The main active ingredient in Ozempic is semaglutide, which is also the key ingredient in Novo's obesity drug Wegovy. Several less efficacious obesity drugs from multiple drugmakers have previously been approved, but bungled launches and serious side effects led to tepid sales and even some market withdrawals. Novo faces looming competition from Eli Lilly (LLY.N), whose weekly injection Mounjaro won U.S. approval for type 2 diabetes in May and is under fast-track review as a weight-loss drug. Amgen (AMGN.O) also has an early-stage, once-monthly obesity drug that is being keenly watched. Elon Musk, the world's richest person and now Twitter owner, has offered his own endorsement of the weight-loss benefits of semaglutide on the social media website.

☆ New obesity drugs win support of doctors and insurers, which could lift these pharma names even higher
▼ + stars: | 2022-11-03 | by ( Christina Cheddar Berk | ) www.cnbc.com time to read: +5 min

They are also increasingly being prescribed by doctors and covered by insurers – a win for patients and for investors. According to Novo Nordisk , the maker of weight-loss drug Wegovy, about 80% of anti-obesity medications are being covered by health insurers, Meacham said. Novo's semaglutide is branded Wegovy as a weight-loss treatment and Ozempic for the treatment of type 2 diabetes. When combined with lifestyle modifications, patients taking Wegovy can sustain a 15% weight loss , according to late-stage clinical trial data. Eli Lilly has a competing drug, Mounjaro, that uses both GLP-1 and a second incretin, glucose-dependent insulinotropic polypeptide, or GIP.

An earlier study in adults showed that the drug did indeed help with weight loss. “We’ve entered the phase where we are seeing the kind of weight loss where teens come to us in tears. In addition to the weight loss, the drug reduced some cardiovascular risk factors, including waist circumference and bad cholesterol. As it turns out, even when people get weight loss surgery, “three years out, there is significant weight gain,” Li said. When a weight loss drug like this is prescribed to patients, that shouldn’t be the end of things, Li said.

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