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Doctors found the woman’s alcohol levels could range between 30 millimoles per liter and 62 millimoles per liter — below 2 millimoles per liter is normal, Zewude said. “I know of over 300 people diagnosed with auto-brewery syndrome and we have over 800 patients and caregivers in our private Facebook support group,” said Cordell, who was not involved in the new case. “But it wasn’t until the seventh visit that an emergency room doctor finally said, ‘I think this sounds like auto-brewery syndrome,’ and sent her to a specialist,” Zewude said. Since 1974, 20 diagnosed cases of auto-brewery syndrome have been reported in English medical literature, according to an April 2021 review. “I believe many people may walk around feeling foggy and just think they are tired when they might be fermenting alcohol.”‘A metabolic storm’There are risk factors for auto-brewery syndrome.
Persons: , , Rahel, Doctors, Zewude, Barbara Cordell, Cordell, , , ” Zewude, Fahad Malik, Malik, Candida, It’s, ” Cordell, Probiotics Organizations: CNN, University of Toronto, Research, Facebook, Toronto, Canadian Medical Association, United Heath Services, State University of New York, Medical University, ” Auto, Locations: Toronto, Binghamton , New York, Africa, Japan, North Carolina
The Food and Drug Administration on Wednesday approved the sale of an antibiotic for the treatment of urinary tract infections in women, giving U.S. health providers a powerful new tool to combat a common infection that is increasingly unresponsive to the existing suite of antimicrobial drugs. The drug will be marketed in the U.S. as Pivya and will be made available by prescription to women 18 and older. It is the first time in two decades that the F.D.A. has approved a new antibiotic for U.T.I.s, which annually affect 30 million Americans. is committed to fostering new antibiotic availability when they prove to be safe and effective.”
Persons: U.T.I.s, Dr, Peter Kim Organizations: Drug Administration, Drug, Research Locations: Europe, U.S
One Leafy Green Needs Refrigeration to Prevent E.Coli
  + stars: | 2024-03-04 | by ( March | At A.M. | ) www.usnews.com   time to read: +4 min
By Dennis Thompson HealthDay ReporterHealthDayMONDAY, March 4, 2024 (HealthDay News) -- Salad lovers, take note: Lettuce is more vulnerable to E. coli contamination than other leafy greens, researchers report. Other leafy greens – spinach, kale and collards – are more resistant to E. coli, a bacteria with toxic strains that can cause severe stomach cramps, bloody diarrhea and vomiting. On kale and collards, E. coli grows slower in warmer temperatures, but can survive longer under refrigeration, researchers found. People can protect themselves by rinsing lettuce, Dong said, although she warned that E. coli bacteria tend to attach themselves tightly to lettuce leaves. Consumers also should store their lettuce in the fridge and pay attention to any food safety recalls involving leafy greens, researchers said.
Persons: Dennis Thompson, , Mengyi Dong, Dong, ” Dong, , Coli, Pratik Banerjee, ” Banerjee Organizations: Microbiology, Duke University in, University of Illinois, USDA, Mayo Clinic Locations: Duke University in Durham, N.C, Urbana, Champaign, University of Illinois Urbana, , U.S
Last year doctors offered to treat Horton’s infection with one of nature’s oldest predators — tiny tripod-looking viruses called phages designed to find, attack and gobble up bacteria. SCIEPRO/Science Photo Library/Getty ImagesThe microscopic creatures have saved the lives of patients dying from superbug infections and are being used in clinical trials as a potential solution to the growing problem of antibiotic resistance. Would the bacteria from her ear help scientists find phages that would treat the eye infections as well? By the following January, the CDC said at least 50 patients in 11 states had developed superbug infections after using preservative‐free artificial tears. It was a qualified success: The antibiotic-resistant bacteria in five patients were eradicated, while several more patients showed improvements.
Persons: Cynthia Horton’s earaches, , , Dwayne Roach, Eager, Horton, Maroya Walters, ” Walters, Tom Patterson, Steffanie, Paul Turner, “ Iraqibacter, Patterson, Strathdee, Tom, ” Strathdee, Tom Patterson's, Rather, Anthony Maresso, ” Maresso, “ It’s, ” Roach, phages, Elizabeth Villa, Jumbo phages, Robert “ Chip ”, ” Schooley, Juliette Robert, Haytham, REA, CDC’s Walters Organizations: CNN, San Diego State University ., US Centers for Disease Control, Center, Therapeutics, UC San Diego School of Medicine, UC, Diego’s, CDC, Yale University, Yale School of Medicine, UC San, UC San Diego, , San Diego, Baylor College of Medicine, Eliava Institute Locations: United States, North America, Pennsylvania, IPATH, Iraq, New Haven , Connecticut, UC San Diego, Turner’s Yale, San, San Diego State, Texas, Houston, Russia, Georgia, Tbilisi , Georgia
Honey For years, people have claimed that eating honey, especially locally-collected honey, is a great way to lessen seasonal allergies. I use honey for the common cold, and it's perfectly safe. "I use honey for the common cold, and it's perfectly safe." Around cold and flu season, Mafi stocks up on garlic for symptom relief for colds. "There is a small amount of evidence that garlic can help reduce the severity and duration of the common cold," Mafi says.
Persons: John Mafi, Mafi, Honey, Timothy Wong, I've, didn't Organizations: Food and Drug Administration, General Internal Medicine, Health Services Research, David Geffen School of Medicine, UCLA, CNBC, British Medical, American Academy of Pediatrics, Cochrane
In our Bombas socks review, style editor Amir Ismael wrote: "My favorite feature on almost every pair of Bombas socks is the cushioned footbeds in its ankle socks and thicker hiking pairs. Bombas Cyber Monday 2023 deals: Quick linksCyber Monday Bombas deals FAQsWhat makes Bombas socks unique? Bombas socks feature seven material improvements from the ordinary pair of socks. To ensure further comfort and durability, Bombas offers a quiz to help find the perfect fit for you. For every Bombas purchase, a donation is given to support a community with socks, underwear, and T-shirts.
Persons: Amir Ismael, I've, we've, you'll, Bombas Organizations: Bombas Locations: Bombas, United States
We've loved Bombas' high-quality socks for years (as you can see from our Bombas socks review), but its underwear, slippers, and loungewear are just as noteworthy. Bombas Black Friday 2023 deals: Quick linksBlack Friday Bombas deals FAQsWhen is Black Friday? Bombas socks feature seven material improvements from the ordinary pair of socks. To ensure further comfort and durability, Bombas offers a quiz to help find the perfect fit for you. For every Bombas purchase, a donation is given to support a community with socks, underwear, and T-shirts.
Persons: We've, you'll, Bombas Organizations: Bombas Locations: Bombas, United States
Antimicrobial resistance (AMR), which the World Health Organization has referred to as the "silent pandemic," is an often overlooked and growing global health crisis. Sakis Mitrolidis | Afp | Getty ImagesMaking matters worse, research has shown that climate change is exacerbating the AMR crisis in several ways. "AMR bacteria is known as a silent pandemic. Extreme heat is fueled by the climate crisis, which makes extreme weather more frequent and more intense. "We hear people talking about this 'silent pandemic,' but it shouldn't be silent.
Persons: Sakis Mitrolidis, Tina Joshi, Joshi, University of Plymouth Robb Butler, Butler, Plymouth's Joshi Organizations: Planck, Biology, Getty, World Health, United, AMR, WHO, Afp, University of Plymouth, CNBC, UN, United Arab Emirates, Polygiene, Aircraft, Bloomberg, Plymouth's Locations: United Nations, Sikorahi, Alexandroupoli, Greece, WHO Europe, United Arab, UAE, Hamburg, Germany
Signage is seen outside of the Food and Drug Administration (FDA) headquarters in White Oak, Maryland, U.S., August 29, 2020. REUTERS/Andrew Kelly/File Photo Acquire Licensing RightsNov 15 (Reuters) - The U.S. health regulator on Wednesday approved CorMedix's (CRMD.O) antimicrobial drug for reduction of catheter-related bloodstream infections (CRBSIs) in patients with kidney disease, allowing the company to launch its first commercial product. The company plans to ready the drug for commercialization by end of the first quarter of 2024, CorMedix CEO Joe Todisco told Reuters. DefenCath, a combination of the antimicrobial active ingredient taurolidine and blood thinner heparin, has previously been rejected twice by the U.S. Food and Drug Administration (FDA) on manufacturing concerns. Ahead of the drug approval, CorMedix said it had changed its heparin supplier and the FDA had inspected its current manufacturing facility and was comfortable with it.
Persons: Andrew Kelly, Joe Todisco, CorMedix, Christy Santhosh, Shailesh Organizations: Food and Drug Administration, FDA, REUTERS, Reuters, U.S . Food, Drug Administration, RBC, DefenCath, Thomson Locations: White Oak , Maryland, U.S, New Jersey, DefenCath, Bengaluru
CNN —The US Centers for Disease Control and Prevention is expanding its infectious disease surveillance program at four major US airports to more than 30 pathogens, including flu, RSV and other respiratory viruses. The program currently operates Covid-19 surveillance at seven major international airports in the United States. The traveler surveillance program was introduced in 2021 when the CDC began collecting nasal swab samples from anonymous international travelers arriving at participating airports who volunteer to get swabbed. The program has collected samples from travelers from more than 135 countries and has sequenced more than 14,000 samples for further analysis. The wastewater program, which was introduced in August 2022, collects wastewater from a single plane using a custom-made collection device.
Persons: Dr, Cindy Friedman, John F, , ” Friedman, Friedman, Ginkgo Bioworks, Matthew McKnight, ” McKnight, Sanjay Gupta, Deidre McPhillips Organizations: CNN, Centers for Disease Control, CDC’s, Health, Boston Logan International Airport, San Francisco International Airport, Dulles International, Washington , D.C, Kennedy International, CDC, Get CNN, CNN Health Locations: United States, Washington ,, New York, Ginkgo
Bariatric Surgery at 16
  + stars: | 2023-10-31 | by ( Helen Ouyang | ) www.nytimes.com   time to read: +4 min
It’s the exact opposite.” The number of teenagers who underwent bariatric surgery more than doubled nationwide between 2010 and 2017 and continues to rise. Seeley emphasizes that weight loss doesn’t simply result from a newly tiny stomach that limits how much people can eat. The crucial roles instead seem to be played by bile acids and antimicrobial peptides in the gut, each of which increase markedly after surgery; Seeley is still sorting out the exact mechanisms of their influence. “Why bariatric surgery works so well is because you’re changing lots of things at the same time,” Seeley says. Most important, bariatric surgery seems to reset, to a lower bound, the body weight that the brain tries to maintain.
Persons: Rodriguez, , , Alexandra, ” Gabriela, ” Rodriguez, Thomas Inge, Randy Seeley, Seeley, ” Seeley, “ I’m, ” Inge, I’d, “ We’ve Organizations: Teen, National Institutes of Health, Lurie Children’s Hospital, University of Michigan Locations: United States, Chicago
Dominique MosbergenDominique Mosbergen is a medical science reporter in The Wall Street Journal’s Health and Science bureau. She covers infectious diseases, antimicrobial resistance and frontiers in medical science, including the science of aging. In 2022, she and her colleagues won a Newswomen's Club of New York's Front Page Award for Breaking News for their coverage of the fall of Roe v. Wade. Previously, Dominique spent a decade as a reporter at HuffPost, where she covered breaking news, U.S. politics, climate change, public health and other issues. As an undergraduate, she studied Russian literature at Columbia.
Persons: Dominique Mosbergen Dominique Mosbergen, Roe, Wade, Dominique Organizations: Health, Science, New, News, Columbia University’s Graduate School of Journalism, Columbia Locations: HuffPost, Russian
The 20 Best Early Labor Day 2023 Sales
  + stars: | 2023-08-23 | by ( Bellamy Richardson | ) www.wsj.com   time to read: +13 min
By Bellamy RichardsonLabor Day may not be until Sept. 4, but you don’t have to wait to take advantage of great Labor Day deals. Here are some of our early favorites; we’ll be continuing to add more early sales as they go live leading up to Labor Day Weekend. BrooklinenThe deal: 15% off sitewideHead over to Brooklinen’s Staycation/Early Labor Day Sale for 15% off bedding, bath and loungewear. There might be something for you at eBags during its Labor Day sale, running now through Sept. 12. LunaThe deal: 20% off sleep productsIf you’ve been craving a good night’s sleep, Luna’s Labor Day Sale might have just the thing to help you out.
Persons: Bellamy Richardson, we’ll, Staycation, unzipping, you’ll, Marigold, Casper, , Luna, Luna’s, It’s, Spinner, puffiness, Stove’s Organizations: Labor, sitewide, Sage, Luna’s Labor, Sherpa, Cook Duo, Outer’s Labor, Navy, TSA, Stove’s Labor Locations: California
Blood, milk, and muscle from cattle, goats, or sheep were all preserved in the pots. The pots contained blood, muscle, and milk proteins, representing several different types of animals. The milk proteins show the Maykop people were also getting their dairy from these animals. One cauldron had both blood and milk proteins. AdvertisementAdvertisementGoing forward, Wilkin thinks analyzing proteins from metal cooking vessels could lead to new discoveries in other locations, too.
Persons: Shevan Wilkin, Wilkin, Viktor Trifonov, Trifonov, It's, Christine Hastorf, wasn't, Sakib, Hastorf Organizations: Service, Archaeological Research, University of California, Getty Locations: Wall, Silicon, Berkeley, Maykopsky District, Adygea Republic, Russia
But the US itself poses the biggest threat to the buck's dominance, according to Benn Steil. Debt-ceiling standoffs and “growing weaponization” could undermine the currency, he said. Get the inside scoop on today’s biggest stories in business, from Wall Street to Silicon Valley — delivered daily. "The biggest threat to the dollar's dominance comes not from competitive alternatives, but from the US government itself," Steil, who's the director of international economics for the Council on Foreign Relations, wrote. "Just as the overuse of antibiotics fuels antimicrobial resistance, excessive use of sanctions prompts targeted countries, as well as potential targets, to reduce their engagement with the US financial system," Steil wrote.
Persons: Benn Steil ., Benn Steil, Biden, Fitch, heightening, Vladimir Putin, that's, Elon Musk, Steil Organizations: Service, Project Syndicate, Council, Foreign Relations, International Monetary Fund, European Union Locations: China, Russia, Wall, Silicon, US, Ukraine
The 8 Best Early Labor Day 2023 Deals
  + stars: | 2023-08-18 | by ( Bellamy Richardson | ) www.wsj.com   time to read: +5 min
By Bellamy RichardsonLabor Day may not be until Sept. 4, but you don’t have to wait to take advantage of great Labor Day deals. Here are some of our early favorites; we’ll be continuing to add more early sales as they go live leading up to Labor Day Weekend. BrooklinenThe deal: 15% off sitewideHead over to Brooklinen’s Staycation/Early Labor Day Sale for 15% off bedding, bath and loungewear. DreamCloudThe deal: 50% off all mattressesDreamCloud is hosting a Labor Day flash sale, with 50% off all mattresses. LunaThe deal: 20% off sleep productsIf you’ve been craving a good night’s sleep, Luna’s Labor Day Sale might have just the thing to help you out.
Persons: Bellamy Richardson, we’ll, Brooklinen, Staycation, unzipping, Casper, Luna, Luna’s, It’s Organizations: Labor, sitewide, Luna’s Labor, Sherpa Locations: California
The 6 Best Early Labor Day 2023 Deals
  + stars: | 2023-08-16 | by ( Bellamy Richardson | ) www.wsj.com   time to read: +4 min
By Bellamy RichardsonLabor Day may not be until Sept. 4, but you don’t have to wait to take advantage of great Labor Day deals. Here are some of our early favorites; we’ll be continuing to add more early sales as they go live leading up to Labor Day Weekend. BrooklinenThe deal: 15% off sitewideHead over to Brooklinen’s Staycation/Early Labor Day Sale for 15% off bedding, bath and loungewear. LunaThe deal: 20% off sleep productsIf you’ve been craving a good night’s sleep, Luna’s Labor Day Sale might have just the thing to help you out. Head over to Tuft & Needle’s Labor Day Sale to save up to 20% off the Original and Mint Mattresses, up to $700 off the Mint Hybrid Mattress, 20% off all bedding and more.
Persons: Bellamy Richardson, we’ll, Staycation, unzipping, Casper, Luna, Luna’s, It’s Organizations: Labor, sitewide, Luna’s Labor, Sherpa Locations: California
Yet recent research suggests that one pill of the drug can be effective in preventing such infections among men who have sex with men if taken within 72 hours after unprotected sex. He added that any guidance from the CDC will help “fill gaps,” provide direction to clinics and offer a framework for using doxyPEP for STI prevention. “Drug resistance when taking doxyPEP is currently being studied in people using this treatment for STI prevention. “There are still many STI prevention and treatment gaps left to fill. “In STI prevention, we’ve been relying on tools that are decades, sometimes centuries old.
Persons: Dr, Jonathan Mermin, , doxyPEP, Stephanie Cohen, , “ We’re, ” Cohen, ” David C, Harvey, ” Harvey, DoxyPEP, someone’s, Annie Luetkemeyer, gonorrhea, ” Luetkemeyer, Connie Celum, Kenya Medical Research Institute —, Jenell Stewart, Stewart, ” Stewart, Suneer Chander, Wisp, ” Chander, Sanjay Gupta, Mermin, Deidre McPhillips Organizations: CNN, US Centers for Disease Control, CDC’s National Center, HIV, CDC, San Francisco Department of Public Health, California Department of Public Health, San Francisco Department of Public, National Coalition, STD, , New England, of Medicine, Zuckerberg San Francisco General Hospital, UCSF, University of Washington, Hennepin Healthcare Research Institute, Kenya Medical Research Institute, Hennepin Healthcare, University of Minnesota, PEP, Food and Drug Administration, CNN Health Locations: United States, San Francisco, Seattle, King County, Washington, Kenya, Hennepin
For these two days, take 25% off select items as well as 15% off select beauty products by using the code CYBER at checkout. Everlane Best of SaleThe deal: Various discounts sitewideLooking to add some classic summer essentials to your wardrobe for the warmer weather? Lands’ End High-Summer SaleThe deal: 50% offHeading to the beach and need a new swimsuit? Our Place Summer SaleThe deal: 20% off select itemsFrom now through July 12, upgrade your cookware collection and take 20% off select items from Our Place for its Summer Sale. Sephora Top Skincare SaleThe deal: Up to 50% off top skincare itemsYou can save up to 50% off top skincare picks through July 15.
Persons: Bellamy Richardson, Alex Mill, , Cabeau, Peter Thomas Roth, Huckberry, Ripstop, Macy’s, Michael Kors, you’ve, Samsonite, Spinner —, , LUNA, Pearl Pink, Kate Somerville, grillers, Gray Organizations: Amazon, Amazon Prime, USA, GOLS, Stainless Steel, Macbook, Walmart, Target, Samsung, LG, Sony, LG Smart, Brooklinen, Cabeau, Soho, Rockies, Black, Nike, Nike Air Max, Saks, Saks Fifth, Sale, Sun, Dyson, Lenovo, Thermoworks, Savings, Urban, Big Deal, Urban Outfitters, Party Locations: California, Kalamata, Bone, Zion, Black, Caribbean, Tres, Wayfair, White
CNN —If TikTok and Reddit influencers are to be believed, the plant-based compound called berberine can be a replacement for such popular diabetes and weight loss drugs as Ozempic and Wegovy. Is berberine’s weight loss effect meaningful? Berberine may enhance the body’s natural production of GLP-1, or glucagon-like peptide 1, a gastrointestinal hormone that’s used in Ozempic and other new weight loss drugs. However, in terms of its weight loss benefits, they are modest at best,” he said. “Metformin lowers blood sugar, and berberine lowers blood sugar,” Levitt said.
Persons: Berberine, , , Caroline Apovian, Justin Ryder, Ryder, Joshua Levitt, Ashurbanipal, ” Levitt, Gaston Ernesto Gonzalez Avila, Levitt Organizations: CNN, US Food and Drug Administration, Harvard Medical School, Center, Weight Management, Wellness, Brigham, Women’s Hospital, Northwestern University’s Feinberg School of Medicine, BMI, National Library of Medicine, FDA, American Chemical Society Locations: Boston, Chicago, Ayurveda, Hamden , Connecticut
REUTERS/Johanna Geron/File PhotoJune 1 (Reuters) - Pfizer Inc (PFE.N) said on Thursday data from late-stage trials showed its experimental combination of antibiotics was effective in treating deadly infections caused by drug-resistant bacteria. Deaths from antibiotic-resistant bacteria, also known as superbugs, have been on the rise globally, and health regulators have called for the development of newer treatments as resistance to older antibiotics grows. The late-stage studies compared the experimental combination of the antibiotics aztreonam-avibactam (ATM-AVI) and existing generic drug metronidazole with a combination of two older antibiotics - meropenem and colistin - to treat complicated intra-abdominal infections and types of hospital-acquired pneumonia. Pfizer said the data from the studies shows the antibiotic combination of ATM-AVI is effective and well-tolerated in treating infections caused by gram-negative bacteria. For patients with types of hospital-acquired pneumonia and ventilator‐associated pneumonia, the cure rate was 45.9% for Pfizer's antibiotic combination with metronidazole, versus 41.7% for other, older treatments.
Persons: Johanna Geron, Leroy Leo, Sriparna Roy, Pooja Desai Organizations: Pfizer, REUTERS, Pfizer Inc, Disease Control, Thomson Locations: Puurs, Belgium, United States, Bengaluru
These Are the Best Pillows for Stomach Sleepers
  + stars: | 2023-05-03 | by ( ) www.wsj.com   time to read: +16 min
By Lisa LombardiIf you’re a stomach sleeper, you’ve likely shopped for squishy, soft pillows in the past. That’s why finding the ideal pillow for stomach sleepers can prove to be difficult. It cushioned my head without allowing it to collapse into the mattress, like some other soft pillows do. Best upgrade pillow for stomach sleepersCozy Earth Silk Pillow $224 at Cozy Earth $ 299 Save $ 75 Silk-filled with a breathable bamboo cover, this pillow is a luxe pick for stomach sleepers who tend to overheat while they sleep. This flexibility proves particularly helpful for stomach sleepers, since getting the right loft is important to avoiding neck discomfort.
12 Best Gifts for a First-Time Dad
  + stars: | 2023-04-11 | by ( ) www.wsj.com   time to read: +7 min
Here are 12 of the best first Father’s Day gift ideas. For the stylish dadFew things are more adorable than teeny baby shoes—especially when they’re paired up with a practically identical pair of kicks for Dad to wear as well. For the sentimental dadGo ahead, pull on the heartstrings—a sentimental gift makes perfect sense, especially for an occasion like Father’s Day. The cap comes in 14 color combinations and can even be personalized with a different word or phrase of your choice. “It’ll make a great prop or photo opp, and you can’t have too many cute new parent pictures!” she says.
Persons: Sarah Grossbart, Rachel Simon You, , Paul Zahn, they’re, Adidas Stan Smith, Lindsay Roberts Schey, “ it’s, Alison Deyette, Josh McBride, Nick Guy, Steve Greenberg, it’s, Kimberly Wolf, Roberts Schey, Beau, , Elisabeth Jones, Hennessy, GiftMeChic, Hannah Redmond, , Comfort, Deyette, ” Wolf Organizations: Polaroid, Adidas Locations: Los Angeles, New York City, Houston, Kiehl’s
[1/2] Former Italian Prime Minister and leader of the Forza Italia (Go Italy!) party Silvio Berlusconi attends a rally in Rome, Italy, April 9, 2022. REUTERS/Remo CasilliMILAN, April 10 (Reuters) - Former Italian Prime Minister Silvio Berlusconi's health condition is steadily improving as he is treated in hospital for a lung infection caused by chronic leukaemia, his doctors said on Monday. Doctors later revealed that Berlusconi had been suffering from Chronic Myelomonocytic Leukaemia (CML) "for some time" and that he had recently developed a pulmonary infection. "Cytoreductive, antimicrobial and anti-inflammatory therapies are producing the expected results, allowing us to express a cautious optimism," Zangrillo and Ciceri said.
More than 12 million courses of Paxlovid have been delivered to pharmacies across the U.S., according to federal data. The FDA staff reviewed Pfizer's mid-to-late stage clinical trials of Paxlovid. In one trial called EPIC-HR, Paxlovid showed an 86% reduction in the risk of hospitalization or death in high-risk adults who hadn't received a Covid vaccine. Paxlovid has been plagued by reports of "rebound" Covid infections, where patients see their Covid symptoms or a positive test return after finishing a five-day course of the oral drug. That was also regardless of patients' risk of severe disease, or whether Covid's omicron variant or an earlier strain was dominant, according to the staff.
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