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Monika Cechova - 3 Cechova - 3 Karen Miga - 2 Carolyn Lagattuta - 2 ” - 1 Kenneth Walsh - 1 ” Walsh - 1 Walsh - 1
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Search resuls for: "Telomere"


5 mentions found


☆ Scientists fully sequence human Y chromosome for the first time
  + stars: | 2023-08-25 | by ( Katie Hunt | ) edition.cnn.com   time to read: +7 min
However, over half of the sequences within the Y chromosome, the smallest and most complicated of the 46 human chromosomes, remained unknown. Now, the same group of researchers has filled in the missing information, publishing a complete Y chromosome sequence Wednesday in the journal Nature. “This new analysis will allow us to better understand the regions of the Y chromosome that have regulatory functions and may encode mRNA and proteins.”Many people begin to lose their Y chromosome in some of their cells as they age, particularly those cells that undergo rapid turnover, such as blood cells. Having a complete Y chromosome genetic reference may help scientists and doctors further explore this potential link. “However, it has been questioned whether loss of the Y chromosome is a biomarker of biological aging or whether loss of the Y chromosome has a direct effect on the health of men,” he said.
Persons: ”, Monika Cechova, Cechova, Kenneth Walsh, ” Walsh, Walsh, it’s, ” Cechova, Charles Lee Organizations: CNN —, University of California, University of Virginia School of Medicine, Human Genome Research, T2T Consortium, Jackson Laboratory, Genomic Medicine Locations: Santa Cruz
☆ Scientists have completely sequenced the human Y chromosome for the first time, with huge implications for heath and evolution research
  + stars: | 2023-08-24 | by ( Jenny Mcgrath | ) www.businessinsider.com   time to read: +7 min
Researchers published two new papers on the human Y chromosome. That's because the Y chromosome is "the most complex, most repetitive chromosome," said Monika Cechova, a postdoctoral researcher at the University of California, Santa Cruz. AdvertisementAdvertisementKaren Miga was one of the researchers involved in fully sequencing the human Y chromosome. The worldwide Y chromosomeFor the single-sequence paper, researchers sequenced the Y chromosome of a single individual of European descent, known as the HG002 genome. Because of all the gaps in the Y chromosome genome reference, researchers haven't fully understood how the chromosome contributes to overall health.
Persons: Karen Miga, Monika Cechova, Carolyn Lagattuta, Pascal Gagneux, wasn't, Gagneaux, Evan Eichler, Cechova, Miga, Gagneux, haven't Organizations: Service, Telomere, University of California, UC Santa Cruz, UC San Diego, Center for Academic Research, Human Genome Research Institute, Jackson Laboratory, Genomic Medicine Locations: Wall, Silicon, Nature, Santa Cruz, Anthropogeny
☆ Scientists solve the genetic puzzle of sex-related Y chromosome
  + stars: | 2023-08-23 | by ( Will Dunham | ) www.reuters.com   time to read: +4 min
Males possess one Y and one X chromosome while females have two X chromosomes, with some exceptions. But until now, the Y chromosome part of the human genome had contained big gaps. In addition to identifying some additional Y chromosome genes, the researchers found that some DNA from the chromosome had been mistaken in previous studies as bacterial in nature. The first complete human genome - albeit with the Y chromosome partial - was published last year. Fully sequencing the Y chromosome adds to this.
Persons: Karen Miga, Carolyn Lagattuta, Arang Rhie, Monika Cechova, Cechova, Will Dunham, Rosalba O'Brien Organizations: University of California, UC Santa Cruz, REUTERS, Rights, Wednesday, U.S ., Genome Research, of California, UCSC, Thomson Locations: Santa Cruz , California, U.S, Handout, Santa Cruz
☆ Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds
  + stars: | 2023-05-04 | by ( Gina Kolata | ) www.nytimes.com   time to read: +1 min
Cells have a molecular clock that determines how long they live. The clocks come in the form of caps on the end of chromosomes — the long twisted strings of DNA carrying the cells’ genes. Every time a cell divides, its telomeres get a little shorter, until finally they get so short that the cell dies. While short telomeres do lead to health problems, long telomeres lead to health problems of their own. Far from extending life, long telomeres appear to cause cancer and a blood disorder known as CHIP, a condition that increases the risk of blood cancers and heart disease.
☆ Humans can't live forever, but we haven't even come close to the limit for how long our bodies could last
  + stars: | 2023-04-19 | by ( Emily Swaim | ) www.businessinsider.com   time to read: +10 min
Mysteries like cellular senescence, telomere length, and DNA methylation hold the keys to our longevity. But so far, no one has figured out how to completely prevent or eliminate harmful senescent cells. DNA methylation is linked to several age-related diseasesTreating or preventing age-related diseases is one of the keys to unlocking longer, healthier lives. Similar to telomeres, DNA methylation is another way scientists can measure your biological age to help predict your life expectancy. For example, telomere shortening can lead to DNA damage, which in turn disrupts your mitochondria.
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