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Moderna and Merck released more positive three-year data Monday on their experimental vaccine, given to patients with the most deadly form of skin cancer in combination with the therapy Keytruda. The vaccine together with Merck's Keytruda improved survival and showed long-lasting efficacy in a midstage study in patients with a deadly form of skin cancer. Melanoma is responsible for the large majority of skin cancer deaths, according to the American Cancer Society. Moderna is also conducting another phase three trial of the vaccine in patients with a type of lung cancer. This year, Merck and Moderna started a two-part mid- to late-stage trial on the vaccine and Keytruda in patients at an advanced stage of a common skin cancer.
Persons: Merck's, Kyle Holen, Keytruda, Stephane Bancel, Bancel Organizations: Moderna, Merck, American Society of Clinical Oncology, CNBC, U.S . Food, Drug Administration, FDA, American Cancer Society Locations: Chicago, U.S, Moderna
The Food and Drug Administration on Friday approved Moderna's vaccine for respiratory syncytial virus for adults ages 60 and above, the company's second-ever product to enter the U.S. market. The approval of Moderna's shot is based on a late-stage trial on older adults, who are more vulnerable to severe cases of RSV. The company's shot is also the only RSV vaccine to be available in a pre-filled syringe, which is designed to make it easier to administer to patients. An advisory panel to the CDC will vote in June on recommendations for the use and intended population of Moderna's shot. Moderna's full-year 2024 sales guidance of roughly $4 billion includes revenue from its RSV vaccine.
Persons: Moderna's, Stéphane Bancel Organizations: Drug Administration, Moderna, Centers for Disease Control, CDC, GSK, Pfizer Locations: U.S
There will be no French fries for the 15,000 athletes at the Olympic Games that open in France in July. Yes, you read that right. In what is being called the biggest restaurant in the world — a 700-foot-long former electrical power plant at the heart of the Olympic Village — there will be no foie gras, either, but vegetarian hot dogs and quinoa muesli will abound. This is a far cry from the classic French cuisine of elaborate sauces and “enough melted butter to thrombose a regiment,” as A.J. Liebling once described a dish.
Persons: Stéphane Chicheri, Charles Guilloy, Liebling Organizations: Olympic Games, Olympics Locations: France
CNN —Filmmaker Payal Kapadia made history Saturday, as she became the first person from India to clinch the prestigious Grand Prix at the 77th Cannes Film Festival, the second highest prize after the Palme d’Or. It is the first Indian movie in three decades to compete in Cannes’ main competition. “Please don’t wait another 30 years to have an Indian film,” she said to the audience. “Indian stars shining bright… These women have scripted history, and inspired the entire Indian film fraternity,” he wrote on the platform. In 1947, filmmaker Chetan Anand took Cannes’ top prize for his film “Neecha Nagar,” becoming the only Indian to win the accolade.
Persons: Payal Kapadia, Palme, ” Kapadia, Greta Gerwig, Lily Gladstone, , Narendra Modi, ” Rahul Gandhi, India’s, Anasuya Sengupta, , Chhaya, Divya Prabha, Stephane Cardinale, Corbis, Hridhu Haroon, Kartiki Gonsalves, Chetan Anand, Neecha, Kapadia Organizations: CNN, Prix, Cannes Film, Cannes, Indian National Congress, Grand, “ Salaam, Hollywood, Cannes ’ Locations: India, Mumbai, Cannes, , “ Salaam Bombay, Kani, Indian
The decision by Spain, Norway and Ireland to recognize an independent Palestinian state reflects growing exasperation with the Israel of Prime Minister Benjamin Netanyahu, even from traditional friends, and suggests that international pressure on him will grow. It does not, however, make it inevitable that other larger European states will follow suit. This year President Emmanuel Macron of France has said such recognition is “not a taboo,” a position reiterated by the French Foreign Ministry on Wednesday. “This decision must be useful, that is to say allow a decisive step forward on the political level,” Foreign Minister Stéphane Séjourné said in a statement about potential recognition. “France does not consider that the conditions have been met to date for this decision to have a real impact on this process.”
Persons: Benjamin Netanyahu, Emmanuel Macron, David Cameron, Stéphane Séjourné, Organizations: French Foreign Ministry Locations: Spain, Norway, Ireland, Israel, France, Palestinian, Europe, United States, “ France
"We as students, faculty and alums who are standing on the right side of history do not stand with Biden," said another Morehouse student, sophomore Anwar Karim. Most recently, Morehouse faculty were split over the decision to award Biden an honorary doctorate degree at the ceremony. Divisions on campus led to at least three meetings between Morehouse President David Thomas and students and faculty. That sentiment was shared by other Morehouse students critical of Biden's visit. But still, Biden's Morehouse visit will come amid a concerted effort by his administration and campaign this week to sharpen his message to Black voters.
Persons: Joe Biden, Karine Jean, Pierre, Biden, He's, Jean, Pierre said, Court's Brown, Morehouse, Stephane Dunn, Calvin Bell, alums, Anwar Karim, he's, David Thomas, Thomas, Karim, Steve Benjamin, Benjamin, Trump, Malik Poole, Biden's Morehouse, Brown, Kamala Harris, Dunn Organizations: U.S, White, Morehouse College, NBC News, Education, Morehouse, Israel, CNN, House, Office, Public, Black, Alpha Kappa Alpha, Saturday, NAACP, Fund, Biden Locations: Israel, Washington , U.S, Gaza, Georgia, Detroit
CNN spoke to 10 students and four faculty members at Morehouse College who had differing opinions on Biden speaking at their school. Jalen Silas Burch, a 19-year-old freshman, told CNN that he feels the president’s speech is a move to “pander” to Black male voters. Biden and Harris previously spoke at Morehouse College in 2022 as part of a major voting rights push with legislation stalled on Capitol Hill. Student volunteers assisting with the graduation ceremony at Morehouse College are also required this year to undergo a virtual de-escalation training with the Morehouse College Police Department before the graduation ceremony, according to an email obtained by CNN. “The number one conversation going on is that this graduation is not for President Biden.
Persons: Joe Biden, Biden, “ There’s, , Colin Royal, Kamala Harris, Morehouse, Cedric Richmond, , Jalen Silas Burch, Calvin Bell, ” Morehouse, ” Michael Henry, Noah Collier, David A, Thomas, Steve Benjamin, Benjamin, Eddie Glaude, Harris, Stephane Dunn, , ” Dunn, CNN’s Kayla Tausche, Victor Blackwell Organizations: Atlanta CNN, Morehouse College, Morehouse, Hamas, Maroon Tiger, Biden, Democratic, CNN, Morehouse College Democrats, Morehouse College ”, Israel, , The Atlanta University Center Student Intercommunal, Biden’s Cabinet, ” Morehouse, , White, Princeton, American Studies, Capitol, South Carolina State University, Howard University, Tennessee State, Secret, Student, Morehouse College Police Department Locations: Washington, Atlanta, Gaza, Georgia, Israel, Morehouse’s
Whether retail investors profit from their bets on GameStop and AMC Entertainment or not, one group of companies looks set to cash in from the frenzied trading: stock exchanges. So-called meme stocks, which gained popularity through social media platforms like Reddit and Twitter (or X), have attracted retail investors looking to make a quick profit. Through this new innovative offer, we will offer retail investors a true one-stop-shop experience for equity trading," he said in May 2023. "The rise of retail options trading is another secular trend we're excited to build on with more platforms coming online for index options trading later this year, giving retail investors expanded access to our products," Howson said on an earnings call to analysts this month. ICE, which owns the New York Stock Exchange and several other exchanges, offers trading in stocks, bonds, commodities, currencies and derivatives.
Persons: Eric Leupold, Deutsche Boerse, Benjamin Goy, Stéphane Boujna, FactSet, David Howson, Howson, Oppenheimer, Hannah Gooch, Peters, Marco Iachini ​, Organizations: GameStop, AMC Entertainment, Twitter, Deutsche Borse AG Deutsche Börse, Frankfurt Stock Exchange, Corona, Deutsche Börse, DB1, Deutsche Bank, Global Equity, Cboe, Wall Street, Intercontinental Exchange, Sanlam Investments, ICE, New York Stock Exchange, Vanda Locations: Germany, U.S, Switzerland, Italy, Amsterdam, Brussels, Dublin, Lisbon, Milan, Oslo, Paris, France, Portugal, Europe
In today's big story, we're looking at the people preparing for the collapse of the financial system . The big storyPreparing for the worstAdobe; Chelsea Jia Feng/BIOpinions fluctuate on the economy, but one group has a decidedly strong take. In the subreddit r/economiccollapse, users are preparing for a Soviet Union-type fall of the US economy , writes Business Insider's Jennifer Sor. Further down the economic totem pole, ALICEs (asset limited, income constrained, employed) are struggling to make ends meet . 3 things in techAlex Wong/Getty Images, STR / Contributor/Getty Images, Stephane De Sakutin/Contributor/Getty Images, Abanti Chowdhury/BIHow Mark Zuckerberg turned against the news.
Persons: , Chelsea Jia Feng, Jennifer Sor, Jennifer, aren't, Tyler, there's, Neil Dutta, Jim Simons, annualized, Alex Wong, Stephane De Sakutin, Abanti Chowdhury, Mark Zuckerberg, Zuckerberg, Rupert Murdoch, Sam Altman, Alyssa Powell, Rick Doblin, Dan DeFrancesco, Jordan Parker Erb, Hallam Bullock, George Glover, Grace Lett Organizations: Service, Business, Chelsea, Macro, Renaissance Technologies, Big Tech, Apple, FDA, FOX Locations: Soviet Union, China, Washington, Beijing, New York, London, Chicago
Moderna on Thursday posted a narrower-than-expected loss for the first quarter as the company's cost-cutting efforts took hold and sales of its Covid vaccine, its only commercially available product, topped estimates. The biotech company booked first-quarter sales of $167 million, with revenue from its Covid shot dropping roughly 90% from the same period a year ago. The company reiterated its full-year 2024 sales guidance of roughly $4 billion, which includes revenue from its RSV vaccine. For the first quarter, Mock said the company is "more encouraged by what we're seeing from a productivity perspective" than the higher sales of its Covid vaccine. Cost of sales was $96 million for the fourth quarter, down 88% from the same period a year ago.
Persons: we've, Stéphane Bancel, Jamey Mock, Mock, OpenAI Organizations: Moderna, LSEG, CNBC, Research, Mock, Merck Locations: Moderna, U.S, America
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailModerna CEO Stephane Bancel on Q1 results: The vaccine platform is coming together very nicelyModerna CEO Stephane Bancel joins 'Squawk Box' to discuss the company's quarterly earnings results, which posted a narrower-than-expected loss for the first quarter as the company’s cost-cutting efforts took hold and sales of its Covid vaccine topped estimates, vaccine pipeline, growth outlook, and more.
Persons: Stephane Bancel Organizations: Email Moderna
The highly anticipated trading debut of private equity group CVC Capital Partners shows that Europe's initial public offering market is back on track, Euronext CEO Stéphane Boujnah told CNBC on Friday. Shares of Amsterdam-listed CVC, one of Europe's largest buyout companies, jumped around 23% on Friday morning. The IPO is widely expected to be one of Europe's largest this year. Boujnah said the Euronext platform, the largest stock exchange in Europe and one of the largest in the world, had welcomed 11 stock listings since the beginning of the year. "That's a signal of both the success of the Euronext platform and the competitiveness of the Euronext platform — and a signal of the IPO market being back," he added.
Persons: Stéphane Boujnah, Euronext's Boujnah, CNBC's, Boujnah Organizations: Capital Partners, CNBC, CVC, Reuters, Euronext Locations: Amsterdam, Europe
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailEuronext CEO says IPO market is back — and the listings pipeline is 'very, very impressive'Euronext CEO Stéphane Boujnah discusses the outlook for initial public offerings in Europe and says that the 11 listings on the platform so far this year show “the worst is over.”
Persons: Stéphane Boujnah, Locations: Europe
The Gaza Civil Defense acknowledged that around 100 bodies were buried in graves at the Nasser hospital before the IDF operation there. Al Mighayyer said at the news conference that the Palestinian Gaza Civil Defense in Gaza “discovered torture marks on [some] bodies.” CNN cannot independently verify these claims. Shoshani wrote in the post: “Misinformation is circulating regarding a mass grave that was discovered at Nasser Hospital in Khan Yunis. The Palestinian Civil Defense in Gaza called on the United Nations to form an international committee to investigate the mass graves at the Nasser complex. Amnesty International has also called for an investigation into the mass graves at the two Gaza hospitals.
Persons: Khan Younis, Mohammed Al Mighayyer, Nasser, Al Mighayyer, Civil Defense “, , He’s, , Gaza “, Nadav Shoshani, Shoshani, Gazans —, Gazans, Israel, Stephane Dujarric, General Organizations: CNN, Authorities, Palestinian Civil Defense, Nasser, Israel Defense Forces, Gaza Civil Defense, Civil Defense, Getty, Palestinian Gaza Civil Defense, Israel’s Defense Forces, IDF, Nasser Hospital, Israel, United, UN, , Amnesty Locations: Gaza, Khan, Rafah, AFP, Palestinian, Khan Yunis, Israel, United Nations, New York, Nasser
The United Nations had commissioned an independent review of the agency in January, before Israel circulated its claims, but those charges gave added significance to the inquiry, whose findings were released on Monday. The report issued a series of recommendations for the agency to protect its neutrality, but said that “Israel has yet to provide supporting evidence” for its accusation that a significant number of agency employees are members of terrorist organizations. The United Nations has fired 10 of the 12 employees accused by Israel. Ireland, which has strongly condemned Israel’s campaign in Gaza, increased aid to UNRWA as other countries were cutting it, he noted. UNRWA has argued that Israel has targeted it with a “deliberate and concerted campaign” to undermine its operations when its services are most needed.
Persons: Israel, Stéphane, António Guterres, Guterres, , Caroline Gennez, , Micheál Martin, Israel’s, Japan —, Matthew Miller, Biden, ” Mr, Miller, Benjamin Netanyahu Organizations: The United Nations, United Nations, UNRWA, United, State Department, , European Union Locations: United States, Gaza, Israel, United, Palestine, Belgium, Ireland, Australia, Canada, Japan
All it took for the crookie to take shape was a baker looking for a diversion, his time-tested croissant recipe and a few cookies for inspiration. It took TikTok to make it go viral. Stéphane Louvard created the crookie almost a year and a half ago when he came up with the idea of putting cookie dough into a croissant and then baking it again. On one day in February, Mr. Louvard sold 2,300 of the pastries at his bakery in a bustling Paris neighborhood. The crookie — Mr. Louvard’s son Nicolas, a business school student, came up with the name — has not just taken social media by storm.
Persons: Louvard, Mr, Louvard’s, Nicolas Organizations: Mr Locations: Paris, Madrid, France
The Teatro alla Scala in Milan, one of the world’s most prestigious and storied opera houses, announced Tuesday that its next leader would be Fortunato Ortombina, who is currently general director of Venice’s opera house, Teatro La Fenice. Ortombina will succeed Dominique Meyer, a respected French impresario who has run La Scala since 2020 and who previously led the Vienna State Opera. “A decision has finally been reached,” Mayor Giuseppe Sala of Milan, who is the chairman of the foundation that runs the opera house, said Tuesday after a board meeting. The appointment of Ortombina ended months of speculation and whispers in the opera world. “After three foreign general directors, Stéphane Lissner, Alexander Pereira and Dominique Meyer, an Italian returns to La Scala,” he said in a statement, which noted that the practice of Italian opera singing had recently been added to UNESCO’s intangible cultural heritage list.
Persons: Fortunato Ortombina, Ortombina, Dominique Meyer, Giuseppe Sala of, Gennaro Sangiuliano, , Stéphane Lissner, Alexander Pereira, Organizations: Scala, Teatro La Fenice, La Scala, Vienna State Opera, Locations: Milan, French, Giuseppe Sala of Milan
CNN —As Sudan marks the grim anniversary of a year-long conflict, aid agencies have warned that the country teeters on the edge of collapse, facing an unprecedented humanitarian crisis that has been largely ignored by the rest of the world. The situation in Sudan is dire, with over 8.4 million people, including 2 million children under the age of 5, forced to flee their homes in the wake of the conflict, according to Doctors Without Borders (MSF). Despite these alarming figures, the international response has been woefully inadequate, with only 5% of the 2024 humanitarian response plan for Sudan funded thus far, Islamic Relief said in a statement. A lack of responseDoctors Without Borders on Friday called on leaders attending the Paris conference “to immediately scale up the humanitarian response” in Sudan. “The warring parties in Sudan have inflicted tremendous suffering on Sudanese from all walks of life,” he said.
Persons: Elsadig Elnour, Volker Türk, Sudan “, , Türk, Stéphane Séjourné, Annalena Baerbock, , Mohamed Badawi, ” Mohamed Osman, ” Osman, Sudan Tom Perriello, Perriello, Ramadan Organizations: CNN, Islamic, Sudanese Armed Forces, SAF, Rapid Support Forces, UN, Human, French, Sudan’s, African Center for Justice, Peace Studies, Paris, Human Rights Watch, , US, State Department Locations: Sudan, France, Paris, , Jazira, Saudi Arabia
Actor Aaron Taylor-Johnson and director Sam Taylor-Johnson have been married since 2012. AdvertisementActor Aaron Taylor-Johnson, 33, and director Sam Taylor-Johnson, 57, have been together for more than a decade. 2009: Aaron proposes to Sam after wrapping the filmSam Taylor-Johnson and Aaron Taylor-Johnson in September 2009. February 2017: Aaron says that the public's fixation on their relationship is 'intrusive'Sam Taylor-Johnson and Aaron Taylor-Johnson in April 2014. March 2021: It's reported that Sam and Aaron will team up for another film togetherSam Taylor-Johnson and Aaron Taylor-Johnson in February 2019.
Persons: Aaron Taylor, Johnson, Sam Taylor, Aaron, Sam, , Here's, John Lennon, Dave M, née Taylor, Wood, Jay Jopling, Anjelica, Jessie Phoenix, Anjelica Jopling, John Lennon's, Julia, Harper's, Sam I'd, , Mike Marsland, IndieWire, Pascal Le Segretain, I'm, We've, Aaron didn't, Simon Hattenstone, Hattenstone, Jonathan Ross, Sam's, Wylda Rae, Peter Kramer, Wylda, R.E.M, Romy Hero, Sang Tan, Taylor, Johnson Sam Taylor, Stewart Wilson, London's, Jordan Strauss, We're, Charles Sykes, Anna Karenina, Aaron Johnson, Angus, Thongs, Tom Ford's, Eric Charbonneau, Jesus, Romy, Joel Ryan, Aaron gushes, Mr Porter, Benjamin Button, she's, HBD, Zoë Kravitz, Karl Glusman's, aron, ohnson, aron T aylor-, aid., ames, ieces', ike, elationship, aron d anced, ong, rowe, eing, ove ✍ 🏼 f, m., Jo, " Sony, ted the of, tarr, Aaron T aylor, ady, roper, I w, hie Turner, elebr, 0s, I, cott, Adve, , ', hou Organizations: Service, Nowhere, Hollywood Reporter, The Telegraph UK, Sunday Times UK, Telegraph UK, The Telegraph, Guardian, Globe, New York Magazine, Hollywood, Artist &, ust, ici, ntr Locations: Jopling, Liverpool, London, Somerset, England, Phoenix, Paris, ife, gan
Nearly 100 people died and more than a dozen were missing after an overcrowded boat sank off the coast of Mozambique, the local authorities said on Monday. The vessel was carrying about 130 people, well above its capacity, Jaime Neto, the secretary of state of Nampula Province, where the disaster took place on Sunday, said on national television. Mr. Neto said the boat was headed to the Island of Mozambique from the town of Lunga. Since October, the southern African country has recorded about 15,000 cases of cholera, a waterborne disease, and 32 deaths, according to government data. Nampula Province has been one of the most affected areas, but Stéphane Foulon, the head of mission for Doctors Without Borders in Mozambique, said that there had been no recent cases reported in the district from which the boat had departed.
Persons: Jaime Neto, Neto, Stéphane Foulon Locations: Mozambique, Nampula Province, Lunga
Oscar Piastri of McLaren during the Formula 1 Saudi Arabian Grand Prix at Jeddah Corniche Circuit in Jeddah, Saudi Arabia on March 9, 2024. But with the Japanese Grand Prix this coming weekend, F1's beleaguered boss Stefano Domenicali will finally be able to provide a rebuttal. F1's growing ambitions in the Middle East and the U.S. have at times transcended the sport. Las Vegas airports dealt with 400 private jets arriving for the Grand Prix, while Singapore saw a 63% increase in September flight arrivals compared to the previous year when its Grand Prix was pushed into October. Third placed Carlos Sainz of Spain and Ferrari celebrates on the podium during the F1 Grand Prix of Italy at Autodromo Nazionale Monza on September 03, 2023 in Monza, Italy.
Persons: Oscar Piastri, Stefano Domenicali, Alexander De Croo, Domenicali, Clive Mason, Stephane Bazire, Bazire, I've, Stefano, Colin Syn, We've, Francois Dumontier, Madeleine Orr, Paul Fowler, Carlos Sainz of, Dan Istitene Organizations: McLaren, Formula, Saudi, Jeddah Corniche, Nurphoto, Getty, United Arab, U.S, Belgian, Formula One, of Australia, Albert, Circuit, F1, Silverstone, CNBC, Las, Prix, Singapore, Singapore Grand Prix, Canadian, Italy's Emilia, Grand Prix, Williams, DHL, Ferrari, of, Autodromo Nazionale Monza Locations: Jeddah, Jeddah Corniche Circuit, Saudi Arabia, Belgium, Monza, Italy, Monaco, United Arab Emirates, Europe, America, Las Vegas, Singapore, Japan, Miami, Grand, Canada, Australia, Carlos Sainz of Spain
Moderna has more to offer beyond its Covid vaccine. The update brings Moderna a step closer to having multiple products on the market, which it badly needs amid plunging demand for Covid shots worldwide. Moderna will chart its post-Covid future Wednesday during its fifth annual "Vaccines Day," an investor event in Boston focused on the company's vaccine portfolio. That includes its combination vaccine against Covid and the flu and a shot against another common herpes virus called cytomegalovirus, or CMV. It also includes a new and improved version of Moderna's Covid shot.
Persons: norovirus, Barr, Moderna, Blackstone, Stéphane Bancel Organizations: Moderna, Epstein, Covid, Blackstone Life Sciences, Blackstone Group Locations: Boston, U.S
In this videoShare Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailModerna CEO on vaccines pipeline: Investing aggressively to bring important medicine to patientsModerna CEO Stephane Bancel joins 'Squawk Box' to discuss the company's annual vaccines day, the announcement of multiple vaccine programs advancing to late-stage clinical trials, Moderna's vaccines pipeline outlook, and more.
Persons: Stephane Bancel Organizations: Email Moderna
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailPopularity of listing in U.S. is a problem for London — not Europe, says Euronext CEOStéphane Boujnah, CEO of pan-European bourse Euronext, discusses the region's IPO pipeline and explains how it is attempting to overcome challenges caused by European fragmentation.
Persons: Stéphane Boujnah Organizations: London, bourse Euronext Locations: Europe
CNN —Haiti’s embattled Prime Minister Ariel Henry says his country’s constitution states that only he and his cabinet can appoint a council for the transition of power, Henry’s office told CNN exclusively on Wednesday. But Henry’s office told CNN that only he and his cabinet can appoint the transitional council and will not simply “deliver the country” to new leaders without following constitutional procedures. “According to the Haitian constitution, only the prime minister with the cabinet can appoint the presenting council. Simon Maina/AFP/Getty ImagesThe United Nations secretary-general’s spokesperson Stephane Dujarric said Wednesday that the transitional council under the CARICOM agreement for Haiti is the path forward. While Henry was out of the country, gangs laid siege to Haiti’s main airport to prevent his safe return.
Persons: CNN —, Ariel Henry, Henry, Jean Junior Joseph, , Simon Maina, Stephane Dujarric, Dujarric, “ It’s, we’ve, that’s, ” Henry, Haiti’s, Jovenel Moïse, Jimmy “, Viv Ansanm, Jean, Martin Bauer, Bauer Organizations: CNN, Haitian, United States International University Africa, Getty, United Nations, UN, Caribbean, International Organization for Migration, Dominican, Food Program, Bauer . Food Locations: Caribbean, Haiti, Kenya, Nairobi, AFP, Puerto Rico, Haiti’s, Dominican Republic, Hispaniola, Dominican, Port
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