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Surgeons removed the kidney of a genetically engineered pig from a critically ill patient last week after the organ was damaged by inadequate blood flow related to a heart pump that the woman had also received, according to officials at NYU Langone Transplant Institute. The patient, Lisa Pisano, 54, who is still hospitalized, went back on kidney dialysis after the pig’s organ was removed. She lived with the transplanted organ for 47 days, Dr. Robert Montgomery, director of the institute, said. The kidney showed no signs of organ rejection. “Lisa is in stable condition, and her left ventricular assist device is still functioning,” Dr. Montgomery said, referring to the heart pump.
Persons: Lisa Pisano, Robert Montgomery, “ Lisa, Dr, Montgomery, Lisa, Organizations: NYU Langone Transplant
Both the American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine support the recommendation, saying low-dose aspirin is safe and not likely to cause complications. Despite all the data, too few pregnant women at risk are taking baby aspirin, and too few doctors recommend it. A 2022 study found that Black women are less likely to be told to take baby aspirin, even when they meet the criteria. In addition, only about one in five families surveyed said they were familiar with interventions like baby aspirin. Having had the condition once, Ms. Felix knew she might develop it again during her second pregnancy, so she decided to take baby aspirin.
Persons: haven’t, Harris, , Elizabeth Cherot, , Allyson Felix, Felix, Cherot Organizations: U.S . Preventive Services Task Force, American College of Obstetricians, Society for, Dimes, Wednesday Locations: U.S
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Organizations: The
Citing rising breast cancer rates in young women, an expert panel on Tuesday recommended starting regular mammography screening at age 40, reversing longstanding and controversial guidance that most women wait until 50. The panel, the U.S. Preventive Services Task Force, finalized a draft recommendation made public last year. In 2009, the task force raised the age for starting routine mammograms to 50 from 40, sparking wide controversy. But now breast cancer rates among women in their 40s are on the rise, increasing by 2 percent a year between 2015 and 2019, said Dr. John Wong, vice chair of the task force. The panel continues to recommend screening every two years for women at average risk of breast cancer, though many patients and providers prefer annual screening.
Persons: John Wong Organizations: U.S . Preventive Services Task Force Locations: U.S, United States
A severely ill 54-year-old woman earlier this month became the second person to receive a kidney transplanted from a genetically modified pig, surgeons at NYU Langone Health in New York announced on Wednesday. The patient, who had both heart failure and kidney failure, was given the organ on April 12, just eight days after receiving a mechanical heart pump. Surgical teams at NYU Langone carried out the two procedures over the course of nine days. The kidney came from a genetically engineered pig provided by United Therapeutics Corporation, a biotech company. The pig carried a gene for producing a sugar called alpha-gal that had been “knocked out,” or blocked.
Persons: NYU Langone, Lisa Pisano, Organizations: NYU Langone Health, NYU, United Therapeutics Corporation Locations: New York, New Jersey
Mammograms can miss tumors in women with dense breast tissue. So for these patients, doctors often include a second scan — ultrasound, for example, or an M.R.I. Though many women see the extra scan as a routine form of prevention, Medicare won’t pay for it, and some patients are left to pick up a hefty tab. But the clinic’s staff said that while her mammogram would be fully covered by Medicare, a so-called supplemental ultrasound was not. “I just don’t understand how something that has been the recommended diagnostic test for years is suddenly not covered by Medicare,” she said.
Persons: Mammograms, Joellen Sommer, Sommer, , Organizations: Medicare Locations: Manhattan
The first patient to receive a kidney transplanted from a genetically modified pig has fared so well that he was discharged from the hospital on Wednesday, just two weeks after the groundbreaking surgery. The transplant and its encouraging outcome represent a remarkable moment in medicine, scientists say, possibly heralding an era of cross-species organ transplantation. Two previous organ transplants from genetically modified pigs failed. In one patient, there were signs that the immune system had rejected the organ, a constant risk. But the kidney transplanted into Richard Slayman, 62, is producing urine, removing waste products from the blood, balancing the body’s fluids and carrying out other key functions, according to his doctors at Massachusetts General Hospital.
Persons: Richard Slayman Organizations: Massachusetts General Hospital Locations: Massachusetts
Teen pregnancy increases the chances that a young woman will drop out of school and struggle with poverty, research has shown. Teenagers are also more likely to develop serious medical complications during pregnancy. Now a large study in Canada reports another disturbing finding: Women who were pregnant as teenagers are more likely to die before their 31st birthday. The trend was observed among women who had carried teen pregnancies to term, as well as among those who had miscarried. “Some people will argue that we shouldn’t be judgmental about this, but I think we’ve always known intuitively that there’s an age that is too young for pregnancy,” he added.
Persons: , , Joel G, Ray Organizations: Michael’s, JAMA Locations: Canada, St, Toronto
What to Know About Xolair and Food Allergies
  + stars: | 2024-02-25 | by ( Roni Caryn Rabin | ) www.nytimes.com   time to read: +1 min
While the drug, Xolair, offers a new layer of protection to people who may have life-threatening reactions to common foods, and especially to those who are allergic to several foods, its use comes with important caveats. Does Xolair cure food allergies? Xolair is not a cure for food allergies, nor can it be used to treat acute reactions. People who take Xolair must continue to avoid foods that they are allergic to. But Xolair can significantly reduce the odds that people with severe food allergies will develop acute reactions if they ingest minute amounts of allergens, like peanuts or eggs in prepared foods, or are exposed to trace amounts in some other way.
Organizations: Drug Administration
A drug that has been used for decades to treat allergic asthma and hives significantly reduced the risk of life-threatening reactions in children with severe food allergies who were exposed to trace amounts of peanuts, cashews, milk and eggs, researchers reported on Sunday. The drug, Xolair, has already been approved by the Food and Drug Administration for adults and children over age 1 with food allergies. It is the first treatment that drastically cuts the risk of serious reactions — like anaphylaxis, a life-threatening allergic reaction that causes the body to go into shock — after accidental exposures to various food allergens. The results of the researchers’ study, presented at the annual conference of the American Academy of Allergy, Asthma and Immunology in Washington, were published in The New England Journal of Medicine.
Organizations: Food and Drug Administration, American Academy of Allergy, Asthma, Immunology, The New England, of Medicine Locations: Washington, The
Passers-by stopped to commiserate with him and to try to lift his spirits. They brought him coffee, platters of food and changes of clothing, and welcomed him to their homes to wash up and get some sleep. “They were so kind, and they just couldn’t do enough,” said Mr. Brodutch, 42, an agronomist who grew pineapples on Kibbutz Kfar Azza before the attacks on Oct. 7. “There was a feeling of a common destiny.”The one-man sit-in mushroomed in the weeks after the attacks. But the sidewalks outside the military headquarters could not contain multitudes, and some people were uncomfortable with the location, which was associated with anti-government protests last year.
Persons: Avihai Brodutch, , Brodutch Organizations: Hamas, Kfar Locations: Tel Aviv, Gaza, , Kfar Azza, Israel, mushroomed
An Alabama Supreme Court’s ruling that frozen embryos in test tubes should be considered children has sent shock waves through the world of reproductive medicine, casting doubt over fertility care for would-be parents in the state and raising complex legal questions with implications extending far beyond Alabama. On Tuesday, Karine Jean-Pierre, the White House press secretary, said the ruling would cause “exactly the type of chaos that we expected when the Supreme Court overturned Roe v. Wade and paved the way for politicians to dictate some of the most personal decisions families can make.”Speaking to reporters aboard Air Force One as President Biden traveled to California, Ms. Jean-Pierre reiterated the Biden administration’s call for Congress to codify the protections of Roe v. Wade into federal law. “As a reminder, this is the same state whose attorney general threatened to prosecute people who help women travel out of state to seek the care they need,” she said, referring to Alabama, which began enforcing a total abortion ban in June 2022.
Persons: Karine Jean, Pierre, Roe, Biden, Jean, Wade Organizations: White House, Air Force Locations: Alabama, California
Women who develop high blood pressure or diabetes in the course of pregnancy are more likely to give birth to children who develop conditions that may compromise their own heart health at a young age, scientists reported on Monday. By the time they are 12 years old, these children are more likely to be overweight or to be diagnosed with high blood pressure, high cholesterol or high blood sugar, compared with children whose mothers had complication-free pregnancies. The research underscores the strong association between healthy pregnancies and child health, though the study stops short of proving a cause-and-effect relationship. The findings come from a government-supported study that has followed an international cohort of 3,300 mother-and-child pairs for over a decade. The research was presented at the Society for Maternal Fetal Medicine’s annual pregnancy meeting in National Harbor, Md.
Organizations: Society, American, of, Gynecology Locations: National Harbor, Md
‘This Is Where I Want to Be’
  + stars: | 2024-02-11 | by ( Roni Caryn Rabin | ) www.nytimes.com   time to read: +1 min
At night, when darkness drenches this community, the twinkling colors are the only lights visible. Eight hundred people used to live here, including families with children who scampered about in the evenings. Even the streetlamps are gone, mowed down when tanks plowed through the narrow lanes as the Israeli army arrived to defend against the attackers. Ms. Khon, 56, and Mr. Shnurman, 62, are the only residents who have returned so far. At night, the silence is eerie, punctured episodically by the thunderous sound of bombs exploding in Gaza.
Persons: Ayelet Khon, Ms, Khon, Shar Shnurman, Shnurman Locations: Gaza
U.S. officials said Israel’s apparent willingness to agree to a cessation of hostilities in return for the release of more hostages being held in Gaza has created a new opening for negotiations. Any new deal would likely include phased releases of hostages, though the White House is hoping that a more ambitious one, possibly leading to the release of all of the remaining hostages, might be possible. The talks were mediated by Qatar, which was negotiating with Hamas, as well as by Egypt. At least some of the officials last met in Warsaw in December, but those discussions stalled over Hamas’s insistence that the remaining hostages be released in exchange for a permanent cease-fire and larger prisoner releases. Israel rejected any permanent cease-fire and was pushing for a shorter pause in fighting.
Persons: William J, Burns, David Barnea, Barnea, Mohammed bin Abdulrahman bin Jassim, Abbas Kamel, Israel Organizations: Qatari, Hamas Locations: Europe, United States, Gaza, Israel, Qatar, Egypt, Thani, Warsaw
After nearly 15 weeks of war, sharp divisions within Israel over the path forward in the Gaza Strip are increasingly coming into the open. A member of Israel’s war cabinet, a general who lost a son in the conflict, urged in a television interview broadcast late Thursday that the country pursue an extended cease-fire with Hamas to free the remaining hostages, a rebuke of the “total victory” being pursued by Prime Minister Benjamin Netanyahu. And in a sign of the growing exasperation among parts of the Israeli public over the government’s failure to free the hostages, relatives and supporters of the captives partially blocked traffic on a major highway in Tel Aviv before dawn on Friday, prompting the police to briefly detain seven for having “participated in disorderly conduct and unlawful behavior.”Israel’s emergency governing coalition is under intense and competing pressures as the war drags on. Right-wing politicians are urging the military to act more aggressively in Gaza, even while Israel is contending with outrage across the globe over the carnage and decimation of so much of the territory. At the same time, the families of hostages are urging concessions to secure their return.
Persons: , Benjamin Netanyahu, Locations: Israel, Gaza, Tel Aviv
They were photographed during an escorted tour with the Israeli military. Image More than 23,000 Palestinians in Gaza have been killed since the war began, according to Gazan health officials. Image Houthi fighters at a protest in Sana, Yemen, on Sunday against U.S.-led airstrikes targeting Houthi military sites. “Nothing’s fair in Gaza,” Mr. Sindawi said in a text message. Although the Israeli military has said it is scaling back its operations in the north, its forces continue to clash with Hamas fighters there.
Persons: Benjamin Netanyahu, Israel, , Netanyahu, ” Mr, Israel ”, Fatima Shbair, Mr, Khaled Abdullah, Hassan Nasrallah, , ” Philippe Lazzarini, Rajab al, Sindawi, Gabi Siboni, Siboni, Fuad Khuffash, Khuffash, hasn’t, Hamas’s, Herzi Halevi, Marco Longari, Jonathan Dekel, Chen, Sagui, Hwaida Saad, Ameera Harouda, Roni Caryn Rabin, Gabby Sobelman, Myra Noveck, Matthew Mpoke Bigg Organizations: Hamas, Credit, United Nations ’, United, Sunday, U.S, Reuters, United Nations, ., Agence France, Jerusalem Institute for Strategy, Security, West Bank, Protesters, Gaza Locations: Gaza, United States, Israel, Hague, South Africa, Iran, Lebanon, Yemen, Red, Sana, Gaza City, Tel, Rafah, Egypt, Nablus, Tel Aviv, Gaza . Credit, American, London , Washington , New York, London, , Washington, U.S
Five years ago, the National Institutes of Health abruptly pulled the plug on an ambitious study about the health effects of moderate drinking. The reason: The trial’s principal scientist and officials from the federal agency’s own alcohol division had solicited $60 million for the research from alcohol manufacturers, a conflict of interest and a violation of federal policy. Now, that scientist and another colleague from the aborted study with alcohol industry ties have been named to a committee preparing a report on alcohol and health that will be used to update the federal government’s guidelines on alcohol consumption. Members of the public can submit comments on the tentative appointments through Wednesday, Dec. 6. Chan School of Public Health, who has said in various financial disclosures that he has accepted money from the alcohol industry, has been nominated to chair the committee.
Persons: Kenneth Mukamal, Eric Rimm, Megan Lowry, Rimm Organizations: National Institutes of Health, Harvard, National Academies of Sciences, Engineering, Medicine, of Public Health Locations: Chan
When armed Hamas terrorists invaded her home on Oct. 7, Karina Engelbert was still recovering from a double mastectomy and breast reconstruction surgery that had gone terribly awry. She was weak and easily fatigued, and a buildup of painful scar tissue on her chest caused tightness, limiting her mobility. He has not received any information about his sister’s condition, and she has not been visited by the International Red Cross, he said. Ms. Engelbert is one of about 240 hostages abducted from Israel, many of whom need urgent medical attention. And then there were those who sustained potentially life-threatening injuries in the raid itself, which killed an estimated 1,200 people, most of them civilians.
Persons: Karina Engelbert, Engelbert, Ronen Engel, Mika, Yuval, Nir, , , , Engelbert’s, Diego Engelbert, ” Mr, Ms Organizations: International, Cross Locations: Gaza, Israel
A Simple Way to Save Premature Babies
  + stars: | 2023-11-17 | by ( Roni Caryn Rabin | ) www.nytimes.com   time to read: +4 min
Preterm babies are those born before 37 weeks of gestation. In preterm infants, delayed clamping leads to improved circulation, less need for blood transfusions and a lower incidence of serious complications, such as necrotizing enterocolitis, or inflammation of the digestive tract. Worldwide, some 13 million premature babies are born every year, and almost a million of them die within a month of birth. A low-cost, low-tech intervention like delayed cord clamping has the potential to save many lives. Many preterm babies in the United States are born by cesarean section and require resuscitation.
Persons: Anna Lene Seidler, , Seidler, Anup Katheria, Katheria Organizations: American College of Obstetricians, University of Sydney, National Center for Health Statistics, Sharp Mary Birch Hospital for Women Locations: Australia, Britain, India, Iran, United States, San Diego
The number of American babies who died before their first birthdays rose last year, significantly increasing the nation’s infant mortality rate for the first time in two decades, according to provisional figures released Wednesday by the National Center for Health Statistics. The spike is a somber manifestation of the state of maternal and child health in the United States. Infant and maternal mortality, inextricably linked, are widely considered to be markers of a society’s overall health, and America’s rates are higher than those in other industrialized countries. Their infants face up to double the risk of dying, compared with white and Hispanic babies. Overall life expectancy has declined in the United States in recent years, too, affecting white Americans as well as people of color.
Organizations: National Center for Health Statistics Locations: United States
A 58-year-old man with heart failure who received a new heart from a genetically modified pig died on Monday, nearly six weeks after receiving the pig organ, University of Maryland Medical Center officials announced on Tuesday. The first patient, 57-year-old David Bennett, died last year, two months after his transplant. He had developed multiple complications, and traces of a virus that infects pigs were found in his new heart. Both of the patients had terminal heart disease when they received the transplanted organs, and neither managed to recover sufficiently to leave the hospital. But while doctors said that Mr. Bennett did not show any signs of acute rejection of the new heart, which is the most significant risk in organ transplants, they said that Mr. Faucette’s transplanted heart had started to display some initial signs of rejection.
Persons: Lawrence Faucette, David Bennett, Mr, Bennett, Faucette’s Organizations: University of Maryland Medical Center Locations: Frederick, Md
About 2 percent of births in the United States involve infertility treatment of some kind, according to the paper. Background: The largest study yetPrevious studies of stroke after infertility treatments have yielded mixed results. What’s Next: A warning for womenIn an interview, Dr. Ananth outlined three possible explanations for a link between stroke and infertility treatment. “We know that women who receive infertility treatment have certain vascular complications, typically an increased risk of pre-eclampsia and placental abruption,” he said. Third, he added, “is that people who receive the treatment receive it for a reason.
Persons: , Cande, Ananth, Robert Wood, Organizations: JAMA, Robert Wood Johnson Medical School Locations: United States, New Jersey
Almost half of the women surveyed said they had held back in talking with a maternity care provider about their questions or concerns, a particularly disturbing finding. Background: Maternal mortality rates have soared in the U.S.Maternal mortality rates in the United States are among the highest in the industrialized world. Maternal mortality rates are two to three times higher among these women than among white and Hispanic women. Nevertheless, the findings suggest serious flaws in the care provided to pregnant women and women giving birth. Birthing women deserve respectful health care, which is strongly linked to positive outcomes, C.D.C.
Persons: they’d, Porter Novelli, you’re, , Wanda Barfield Locations: U.S, United States
From there it spreads, becoming a so-called flesh-eating infection that extends quickly beyond the wound into healthy tissue. The bacterium also spreads when people who are immunocompromised or have liver disease eat raw oysters that are contaminated. Physicians warn patients with these conditions against eating raw oysters, which become infected by seawater they filter for food. An open wound means any cut, scrape or other abrasion that might allow the bacterium into your body. If you develop a skin infection, let your health provider know quickly — this is an infection that can spread rapidly.
Persons: beachgoers, It’s, ” Dr, Schaffner, “ Don’t Locations: Connecticut
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