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☆ Big pharma is at a crossroads, as J&J, Merck and others prepare to lose heaps of revenue from blockbuster drugs
▼ + stars: | 2024-01-28 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +12 min

Bristol Myers Squibb's Eliquis is a blood thinner used to prevent clotting, to reduce the risk of stroke. Bristol Myers Squibb's Opdivo is an immunotherapy used to treat cancers, including melanoma and lung cancer. Investors will get updates on Merck and Bristol Myers Squibb's plans for the years ahead when they report earnings on Thursday and Friday, respectively. That's unlike generics, which are cheaper copycats of small-molecule drugs like Bristol Myers Squibb's Eliquis. Bristol Myers Squibb is also testing a new form of Opdivo, which is currently administered into a patient's veins.

Persons: Johnson, William Blair, Matt Phipps, Bristol Myers, Johnson's, Merck's Keytruda, J's Stelara, Opdivo, Phipps, biosimilars, Eliquis, Biosimilars, Humira, JB Reed, Samsung's, Piper Sandler, Christopher Raymond, AbbVie, Raymond, Chris Schott, Schott, Robert Davis, Keytruda, Davis, JPMorgan's Schott, Bristol Myers Squibb, George Frey, J, Amgen, J confidentially, Mike Perrone, It's, Anna Moneymaker Organizations: New York Stock Exchange, Johnson, NYSE Big, Bristol Myers Squibb, Merck, Biden, William Blair & Company, CNBC, Guggenheim, Bristol, Leerink Partners, Bloomberg, Getty, Bioepis, JPMorgan, JPMorgan Health Care, Moderna, Bristol Myers, Karuna Therapeutics, Hardy, Huntsman Cancer Institute, University of Utah, Reuters, Teva Pharmaceuticals, Pharma, U.S . Department of Health, Human Services Locations: drugmakers, EY, Europe, U.S, Cambridge , Massachusetts, Arda, EY's Americas, Bristol, Salt Lake City , Utah, Washington , DC

☆ A rogue star could save Earth from extinction in a billion years by knocking it out past Pluto
▼ + stars: | 2023-12-05 | by ( Marianne Guenot | ) www.businessinsider.com time to read: +3 min

An unexpected rescue mission could come in the form of a star flying by the solar system. There's a slim chance the star could pull the Earth to a more habitable zone, a study suggested. The researchers ran 12,000 simulations to see what would happen if a star passed within 100 astronomical units (about 9.3 billion miles) from Earth. In 92% of cases, the solar system would remain almost intact even as a star passed by the solar system. In some simulations, Earth remained in the solar system but was pulled to a region beyond Pluto that's about 10% cooler than our current orbit.

Persons: —, Sean Raymond, there's, Raymond, that's Organizations: Service, University of Bordeaux, Planetary Science Institute, New, Royal Astronomical Society Locations: France, Tucson , Arizona

☆ Everything is lining up right for these stocks, according to Piper Sandler
▼ + stars: | 2023-11-03 | by ( Brian Evans | ) www.cnbc.com time to read: +2 min

As the market gets off to a strong start for the new month, Piper Sandler sees the stars aligning for certain stocks. All stocks on the Piper Sandler list have an overweight rating. Piper Sandler's high-conviction list comes as stocks head for their best week of the year . E-commerce giant Amazon made the Piper Sandler list, underpinned by both its earnings growth and momentum heading into future results. The firm also noted that Amazon stock is headed toward its 52-week high and could break out above $146 per share.

Persons: Piper Sandler, Piper Sandler's, Thomas Champion, Lululemon, LULU, Abbie Zvejnieks, Zvejnieks, Amgen, Christopher Raymond, Raymond Organizations: Federal Locations: American, ecommerce

The logo for AbbVie is displayed on a screen at the New York Stock Exchange (NYSE) in New York City, New York, U.S., November 17, 2021. Morningstar analyst Damien Conover said he had already factored in a hit to Imbruvica from the Medicare price negotiations, so the update on impairment was not "overly significant to our view." Humira's global third-quarter sales fell 36% to $3.55 billion, but topped analysts' estimates of $3.48 billion, according to LSEG data. AbbVie in July trimmed its 2023 view for Humira sales erosion to 35%, from 37% earlier. The company's newer immunology drugs Skyrizi and Rinvoq generated sales of $2.13 billion and $1.11 billion, respectively, ahead of analyst expectations of $2.10 billion and $1.02 billion.

Persons: Andrew Kelly, girding, AbbVie, Imbruvica, Morningstar, Damien Conover, Humira, Piper Sandler, Christopher Raymond, Ingelheim, Leroy Leo, Christy Santhosh, Maju Samuel, Bill Berkrot Organizations: New York Stock Exchange, REUTERS, U.S, Medicare, Analysts, Sandoz, AbbVie, Thomson Locations: New York City , New York, U.S, The Illinois, Bengaluru

☆ Kohl’s holiday look previews the retailer’s plans to snap out of sales slump
▼ + stars: | 2023-10-19 | by ( Melissa Repko | In Melissa-Repko | ) www.cnbc.com time to read: +8 min

Melissa Repko | CNBCAs shoppers head to Kohl's stores this holiday season, they will see gift ideas, Christmas ornaments and a potential glimpse of the retailer's future. Kohl's has leaned in by opening more Sephora shops inside of its stores. It'll be a bigger part of this holiday season. A year ago, roughly half of Kohl's stores had a Sephora shop. Pet merchandise is getting more square footage at Kohl's stores.

Persons: Merchant Nick Jones, Melissa Repko, Tom Kingsbury, Michelle Gass, Levi Strauss, Kohl's, Kingsbury, Christie Raymond, Covid, Raymond said, splurge, It'll, Raymond, Sephora, it's, Nick Jones, It's, Jones, Fido Organizations: CNBC, Burlington Stores, Franchise Group, Kohl's, Marks, ASDA, Walmart, Bed Locations: Ramsey , New Jersey, Kohl's

☆ Ukrainians forced to become Russian citizens, US-backed research finds
▼ + stars: | 2023-08-02 | by ( Anthony Deutsch | ) www.reuters.com time to read: +3 min

REUTERS/Gleb GaranichAMSTERDAM, Aug 2 (Reuters) - Ukrainians living in Russian-occupied territory are being forced to assume Russian citizenship or face harsh retaliation, including possible deportation or detention, U.S.-backed research published on Wednesday said. A series of decrees signed by Russian President Vladimir Putin compel Ukrainians to get Russian passports, in violation of international humanitarian law, the report said. Ukrainians in occupied territory who do not seek Russian citizenship "are subjected to threats, intimidation, restrictions on humanitarian aid and basic necessities, and possible detention or deportation – all designed to force them to become Russian citizens," the report said. "What is concerning here is that it represents, basically, a violation of the Hague and Geneva Conventions," said Executive Director Nathaniel Raymond of the Humanitarian Research Lab at the Yale School of Public Health. The report was released as part of the Conflict Observatory program, with the support of the U.S. State Department and conducted by research partner the Yale School of Public Health's Humanitarian Research Lab.

Persons: Gleb Garanich AMSTERDAM, Vladimir Putin, Mikhail Mishustin, Nathaniel Raymond, Raymond, Putin, Anthony Deutsch, Giles Elgood, Lisa Shumaker Organizations: Moscow, REUTERS, Yale University, Russian, Hague, Yale School of Public Health, Kremlin, International Criminal Court, U.S . State Department, Yale School of Public, Research, Thomson Locations: Mayorsk, Ukraine, Moscow, Luhansk, Donetsk, Kherson, Zaporizhzhia, Russia, Russian, Ukraine's Donetsk, Geneva

☆ Want to know how to get ready for the rise of AI? Dig into the past.
▼ + stars: | 2023-07-20 | by ( Jacob Zinkula | ) www.businessinsider.com time to read: +7 min

It's why top researchers are looking to the past as a guide to predict how generative AI could affect workers' jobs in the years and decades to come. "It's possible that in the end, we get better jobs, but in the short term, there's a lot of disruption," Mollick said. But Raymond warned that AI could produce some less-desirable outcomes for customer-service workers, particularly if customer-support chatbots become much more capable and advanced. The extent to which AI displaces jobs will depend on how quickly it scales what Mollick calls the "three levels" of work: tasks, jobs, and systems. Instead, what I would be thinking about is: How do you figure out how to use it to do your job better?"

Persons: Ethan Mollick, Mollick, Carl Benedikt Frey —, Frey, Lindsey Raymond —, —, Raymond, that's, chatbots, Oded, There's Organizations: Service, University of Pennsylvania's Wharton School, MIT Sloan School of Management, White, National Bureau of Economic Research Locations: Wall, Silicon, Oxford, COVID, Columbia

☆ Boeing launches data tool to chart path to net-zero emissions target
▼ + stars: | 2023-05-17 | by ( ) www.reuters.com time to read: +2 min

WASHINGTON, May 17 (Reuters) - Boeing Co (BA.N) said on Wednesday it is rolling out a data modeling tool aimed at helping airlines and policymakers determine the quickest, most efficient path to reducing aviation emissions to zero by 2050. Boeing unveiled a beta version of Cascade in July 2022 but it was not publicly available. The public launch of Cascade comes just days after U.S. Transportation Secretary Pete Buttigieg met with counterparts from Canada, the United Kingdom and Singapore at the Asia-Pacific Economic Cooperation forum to discuss investments in sustainable aviation fuel. On Tuesday, Reuters reported that European Union countries are set to finalize SAF targets for airports despite some pushback from airlines. “Our intent is to scale SAF and help it scale by first ... examining what has to change in an airplane to be 100% compatible with (SAF),” Raymond said.

☆ Boeing has unveiled a new plane for its 'ecoDemonstrator' program — a modified 787. See all 10 of the company's testbed jets.
▼ + stars: | 2023-05-03 | by ( Taylor Rains | ) www.businessinsider.com time to read: +8 min

Boeing announced a new addition to its fleet of ecoDemonstrator aircraft on Thursday — a Boeing 787-10 Dreamliner. While not every experimental technology makes it onto a future Boeing jet, about a third actually have. 2014: Boeing 787Boeing 787 ecoDemonstrator. BoeingIn 2014, the planemaker debuted its second ecoDemonstrator — a Boeing 787 Dreamliner. The 787 ecoDemonstrator tested 35 projects, including a collaboration with Delta Air Lines to generate real-time turbulence reports.

Piper Sandler said several positive catalysts are in sight for Biogen over the next several quarters. The firm named the foremost catalyst for Biogen as Alzheimer's treatment Leqembi , which it co-developed with Japanese pharmaceutical company Eisai. Specifically, while share today is minimal (0.7% of patients), docs project this share to almost quadruple within 6 months," Raymond wrote in a Monday note. Aduhelm is the controversial Alzheimer's treatment developed by Biogen and Eisai, whose sales fell below Wall Street's expectations as its efficacy was called into question. "For our part, we think Leqembi has set a high bar – especially with regard to safety," said Raymond.

WASHINGTON, Feb 14 (Reuters) - Russia has held at least 6,000 Ukrainian children - likely many more - in sites in Russian-held Crimea and Russia whose primary purpose appears to be political re-education, according to a U.S.-backed report published on Tuesday. The report said Yale University researchers had identified at least 43 camps and other facilities where Ukrainian children have been held that were part of a "large-scale systematic network" operated by Moscow since its February 2022 invasion of Ukraine. Some of the children were moved through the system and adopted by Russian families, or moved into foster care in Russia, the report said. Ukrainian prosecutors have said they are examining allegations of forced deportation of children as part of efforts to build a genocide indictment against Russia. "This network stretches from one end of Russia to the other," Raymond said, adding that researchers believed that the number of facilities in which Ukrainian children have been held exceeds 43.

☆ Russian forces have relocated at least 6,000 Ukrainian children to camps since start of war, new report says
▼ + stars: | 2023-02-14 | by ( Amanda Macias | ) www.cnbc.com time to read: +4 min

WASHINGTON — Russian forces have moved at least 6,000 Ukrainian children to camps and facilities across Russia for forced adoptions and military training, according to a new report. The allegations detailed in the 35-page report, such as the abduction or detention of children, may constitute war crimes or crimes against humanity. Earlier this month, Ukraine's prosecutor general, Andriy Kostin, said that regional authorities have logged more than 65,000 Russian war crimes since Moscow invaded Ukraine nearly a year ago. Kostin said his teams have also documented more than 14,000 Ukrainian children forced into adoption in Russia. At the time, U.S. Secretary of State Antony Blinken said the conduct may breach international humanitarian agreements and constitute war crimes.

☆ If your employees don't see you taking vacations, they may not ask for time off. Here's how to lead by example.
▼ + stars: | 2022-10-17 | by ( Jennifer Ortakales Dawkins | ) www.businessinsider.com time to read: +5 min

"That means people effectively are not taking holidays at all because you're constantly needing to work." But founders and executives told Insider that company leaders can ensure their employees take the time they need by setting expectations, building trust, and leading by example. Companies with an unlimited vacation policy should also have guidelines to help employees use it effectively. When founders take time off, employees follow suitWhen leaders take time off — and actually disconnect from work — they set an example for their employees. If you've noticed some employees haven't taken too much time off, Zimmerman suggested having a conversation to ask what might be discouraging them from taking vacations.

☆ The North Face is renaming its fleece jackets and spotlighting the Sherpa people
▼ + stars: | 2022-09-23 | by ( Brahmjot Kaur | ) www.nbcnews.com time to read: +5 min

The North Face is dropping the word “sherpa” from the name of its fleece jackets this fall, using the opportunity to highlight the heritage of the Sherpa people. The collection, which was called sherpa fleece jackets and vests, will now be called “pile” fleece, as will all of the company's fleece products moving forward. A Women's High Pile Nuptse Jacket by The North Face. The North Face has credited the Sherpa people for helping guide the company’s athletes for decades during expeditions in the Himalayan mountains. The North Face isn’t the only company to use the word "sherpa" to describe products.

☆ Founders of Canadian relationship app Couply talk gaining traction after winning Collision 2021 pitch competition
▼ + stars: | 2021-06-29 | by ( Sarah Finkel | ) www.businessinsider.com time to read: +5 min

The Canadian relationship app Couply won the 2021 pitch competition hosted by Collision, a Toronto-based technology conference attended by thousands of industry giants. Naturally, you turn to the app store for some guidance, only to find that the selection of relationship apps is rather slim in comparison to dating apps. That was the ideation process behind Canadian startup Couply, founded by Tim Johnson and Denesh Raymond. It's a free relationship app designed to inspire couples to deepen their connection with fun features like personality quizzes, which then help aid the process of planning dates that are mutually enjoyable. "This kind of drills into that core sentiment of Couply, which is to get out there and do things with your partner in the real world," Johnson told Insider.

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