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And yet, the brain does incredible things," said Matt Angle, CEO and founder of Paradromics, in an interview with CNBC Tech: The Edge. The trial would follow competitor Neuralink, which implanted a chip into a patient's brain in March this year. "Paradromics' mission is to transform otherwise untreatable health conditions in brain health into solvable technology problems. "Paradromics can take the science and apply the right engineering to get us from research to medical device," he added. "We see that the first million people to get brain computer interfaces are going to be getting them to treat severe medical conditions," Angle said.
Persons: Matt Angle, Elon Musk, Angle, Vikash Gilja, Gilja, we're Organizations: CNBC Tech, CNBC Locations: Austin , Texas
We're fundamentally building a medical device to serve unmet needs. What that does is it allows us to connect to the brain and receive data from the brain. And so Paradromics can take the science and apply the right engineering to get us from research to medical device. I work on developing processes or selecting the materials that we would like to use to build our cortical module, which is the brain implant portion of our system. We see that the first million people to get brain computer interfaces are going to be getting them to treat severe medical conditions.
Persons: Matt Angle, Paradromics, They're, I'm, Kimiko Nakajima, we're Organizations: BCI
Rob Burrow, a rugby standout who overcame his diminutive stature with fleetness and ferocity to become an eight-time champion of Britain’s Super League and who was later hailed for raising awareness of motor neuron disease after being diagnosed with it in 2019, died on Sunday. His death — from M.N.D., a group of neurological disorders that includes amyotrophic lateral sclerosis, or A.L.S., also known as Lou Gehrig’s disease — was announced by the Leeds Rhinos, the British club with which he spent his entire 17-year professional career. It did not say where he died. Doubted at every turn for his small stature — he was about 5-foot-5 and 150 pounds — Burrow nevertheless became a star, earning nicknames like Mighty Atom and Pocket Rocket in the British tabloids. He was sapped of his physical gifts, however, when he was diagnosed with his neurological disorder at 37, just two years after his retirement in 2017.
Persons: Rob Burrow, Lou Gehrig’s, , Burrow Organizations: Britain’s Super League, Leeds Rhinos Locations: M.N.D, British
CNN —Former rugby league star Rob Burrow, whose quiet strength and relentless campaigning captured the hearts of many Britons after he was diagnosed with motor neuron disease (MND), has died aged 41, his former team Leeds Rhinos announced on Sunday. Rob Burrow became a Leeds Rhinos legend during his rugby league career. “Rob Burrow had a huge heart. Kevin Sinfield carries Rob Burrow across the marathon finish line. Rob Burrow, wife Lindsey (who ran the half marathon), daughters Macy and Maya and Kevin Sinfield, who ran the full marathon, all pose for a picture after the Rob Burrow Leeds Marathon.
Persons: Rob Burrow, Lindsey, Kevin Sinfield, Burrow, Daniel L Smith, Prince William, Sinfield, , “ Rob Burrow, ’ Catherine, Jackson, Macy, , Danny Lawson, Shields, Maya, MND ”, ” Burrow, Burrow’s, ” Sinfield, Rishi Sunak, Keir Starmer, Starmer, Rob, Sunak Organizations: CNN — Former, Leeds Rhinos, MND, league, Rugby League, England, Super, League, Marathon, Headingley Rugby Stadium, Headingley, British, Labour Party Locations: Leeds, England, British, Lindsey, Britain
The in-house AI chip efforts have yet to make a major dent in Nvidia's grip on the market. 'Parity with CUDA'Internally at Amazon, Nvidia's CUDA platform is repeatedly cited as the biggest roadblock for the AI chip initiative. AdvertisementAn obvious response to this would be to have cloud customers use Amazon's own AI chips instead. AdvertisementFor example, AWS's AI chips still have "compatibility gaps" in certain open-source frameworks, making Nvidia GPUs a more popular option. Don't count Amazon outDespite Amazon's AI chip struggles, the effort seems to have caught the attention of Nvidia's CEO Jensen Huang.
Persons: , Bernstein, Stacy Rasgon, I'm, Rasgon, Adam Selipsky, Jensen Huang, Andy Jassy, Inferentia, Trainium, We're, Snowflake's, Sridhar Ramaswamy, Eóin Noonan, Ramaswamy, James Hamilton, Jassy, Gartner, Amazon's, Huang Organizations: Service, Microsoft, Google, Business, Nvidia, Intel, Amazon, BI, Annapurna, NVIDIA CUDA, Netflix, Neuron, AWS, Amazon VP, James Hamilton Amazon, Amazon SVP Locations: Inferentia, Toronto, Canada, CUDA
"I'm not aware of anyone using AWS chips in any sort of large volumes," Rasgon told Business Insider, referring to Amazon's AI chips. This time, the idea is to avoid paying for expensive Nvidia GPUs, while still providing cloud customers with powerful AI services. An obvious response to this would be to have cloud customers use Amazon's AI chips instead. However, some of the largest AWS customers have not been willing to use these homegrown alternatives, the documents said. For example, AWS's AI chips still have "compatibility gaps" in certain open-source frameworks, making Nvidia GPUs a more popular option.
Persons: , Stacy Rasgon, Bernstein, I'm, Rasgon, Adam Selipsky, Jensen Huang, Andy Jassy, Inferentia, Trainium, Omdia, Snowflake's, Sridhar Ramaswamy, Eóin Noonan, CUDA, Ramaswamy, James Hamilton, Jassy, Gartner, Huang Organizations: Service, Microsoft, Google, Business, Services, Nvidia, Intel, Amazon, NVIDIA CUDA, Netflix, Neuron, AWS, NVIDIA, Amazon VP, James Hamilton Amazon, BI Locations: CUDA, Toronto
Now, after the lab team’s decade of close collaboration with scientists at Google, that data has turned into the most detailed map of a human brain sample ever created. The result is an interactive 3D model of the brain tissue, and the largest dataset ever made at this resolution of a human brain structure. And of course, it would reveal many more problems, things we hadn’t expected.”What about mapping an entire human brain? “Much of what we think we understand about the human brain is extrapolated from animals, but research like this is critical for revealing what truly makes us human. “Each human brain is a vast network of billions of nerve cells,” said Sporns, distinguished professor of psychological and brain sciences at Indiana University.
Persons: Jeff Lichtman —, Harvard University —, , Lichtman, Harvard University That’s, Viren Jain, ” Jain, Jain, there’s, we’re, , ” Lichtman, haven’t, Michael Bienkowski, ” Bienkowski, Andreas Tolias, Berger, Olaf Sporns, Sporns Organizations: CNN, Harvard University, Google, Google Research, Lichtman, Harvard, Cisco, University of Southern California’s Keck School of Medicine, , Stanford University in, Indiana University Locations: Stanford University in California
Elon Musk said Neuralink successfully implanted its first brain chip in a human. Here's everything we know about the surgery that replaces a portion of your skull. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . AdvertisementElon Musk said his brain-chip startup implanted its device in its first human patient on Monday. Here's what we know about the process, according to videos from the startup, as well as media reports.
Persons: Elon Musk, Neuralink, , Musk Organizations: Service, Elon, US Food and Drug Administration
NEW YORK (AP) — According to Elon Musk, the first human received an implant from his computer-brain interface company Neuralink over the weekend. Neuralink reposted Musk's Monday post on X, but did not publish any additional statements acknowledging the human implant. In its September announcement, Neuralink said the wires would be surgically placed in a region of the brain that controls movement intention. The initial goal of the so-called brain computer interface is to give people the ability to control a computer cursor or keyboard using their thoughts alone. There are more than 40 brain computer interface trials underway, according to clinicaltrials.gov.
Persons: Elon Musk, Musk, Neuralink, Gehrig’s Disease, ___ Laura Ungar Organizations: Twitter, Associated Press, Drug Administration Locations: Columbia , Missouri
Elon Musk claimed on X that Neuralink's first human patient received their brain implant. AdvertisementElon Musk on Monday claimed in a post on X that a Neuralink brain implant has, for the first time, been inserted into a human patient's brain. "The first human received an implant from @Neuralink yesterday and is recovering well," Musk wrote. AdvertisementMusk previously said the Neuralink device would record and stimulate brain activity, acting as a "Fitbit in your skull," and claimed the implant would eventually "solve" conditions including autism and schizophrenia . "However, any for-profit medical device company also has a vested interest in generating a consumer base, which is why they make the sometimes grandiose claims they do."
Persons: Elon Musk, Musk, , Elon, Stephen Hawking, Hilary Brueck, Neuralink, Tesla, Lou Gehrig's, Insider's Brueck, Randy Bruno, Bruno, that's, Jason T, Eberl, Albert Gnaegi, Healthline Organizations: Service, Business, SpaceX, FDA, Reuters, Columbia University, Albert Gnaegi Center for Health, Saint Louis University
A look at the Neuralink brain chip. Apple is set to launch its Vision Pro headset on Friday in what it describes as its big foray into "spatial computing." That space is essentially your head, with the Vision Pro built to create a canvas that emerges before your eyes while you wear it. question, the Vision Pro is also a response to the growing suite of headgear that Mark Zuckerberg has been creating at Meta. Products include the mixed reality Meta Quest Pro and Meta Quest 3, which, like the Vision Pro, are designed to be worn over your head.
Persons: , they've, Elon Musk, Musk, Neuralink's, Stephen Hawking, Neuralink, Mark Zuckerberg Organizations: Service, Business, Samsung, IDC, Welfare, China's Ministry of Industry, Information Technology, stoke, Apple, Meta, Products, company's Locations: Silicon, Neuralink's
New Delhi CNN —Elon Musk’s controversial startup Neuralink has implanted a chip in a human brain for the first time, the billionaire said in a post on his X platform late Monday. The operation took place on Sunday and the patient was recovering well, he added. “Initial results show promising neuron spike detection,” the world’s richest man said on X, the social media platform he owns. In May last year, Neuralink received FDA clearance for human clinical trials, and a few months later, the startup began recruiting patients with quadriplegia caused by cervical spinal cord injury or amyotrophic lateral sclerosis (ALS). Trial patients will have a chip surgically placed in the part of the brain that controls the intention to move.
Persons: New Delhi CNN — Elon, Stephen Hawking, , Neuralink Organizations: New, New Delhi CNN Locations: New Delhi
Scientists from Tufts and Harvard created microscopic robots from human cells. AdvertisementScientists have created tiny biological "robots" from lung cells that they hope could one day travel around our bodies, regenerating damaged tissues and treating disease. Their research, published Thursday in the journal Advanced Science, raises new questions about how human cells assemble and work together. The same research team had previously created similar tiny robots, or xenobots, from cells sourced from embryos of the African clawed frog. AdvertisementAlhough they're created from human cells, Levin said the anthrobots didn't have a full life cycle and so aren't considered as fully-fledged organisms.
Persons: , TuftsNow, Michael Levin, they're, Levin Organizations: Tufts, Harvard, Service, CNN, US Food and Drug Administration
I told my speech therapist that I was frustrated that I haven’t been able to write fiction since experiencing a traumatic brain injury — which means that I am still, after nearly two years, unable to do my job. Over 1.5 million Americans experience a traumatic brain injury each year. The toll of traumatic brain injuries and the mystery of how the brain repairs itself, or doesn’t, is still perplexing and under-researched. I had to invent a new process in order to tackle the project: ideas inscribed one at a time, thought by thought, sentence by sentence, on note cards, each composed over days, weeks, months. Once there was a queen who fell under a spell, causing her to sink into a deep sleep for a long, long time.
Persons: I’ve, , me holler, I’d, that’s, snowflakes, I’m, It’s, , , giveth, Lord taketh, Keats, Butler, Vonnegut, unstuck, Weeks Locations: Florida,
There's a new stack of hardware, software, tools, and services that will power AI applications for years to come. Cloud 2.0Another key point here: Most AI developers already know how to use CUDA and Nvidia GPUs. Arguably, Nvidia has already created an AI cloud platform – as AWS once did for the Cloud 1.0 era. James Hamilton is an AWS cloud infrastructure genius who can take on Nvidia, even if the chipmaker has a major head start. Her startup spent months building a data center from scratch to help customers train AI models.
Persons: , Jensen Huang, Nvidia Rick Wilking, Andrew Ng, CUDA, Michael Douglas, Bernstein, Douglas, Luis Ceze, Ceze, It's, Andy Jassy, Adam Selipsky, James Hamilton, Oren Etzioni, Claude, Dario Amodei, Anthropic Anthropic, Noah Berger, Sharon Zhou, Zhou, Lamini didn't, Etzioni Organizations: Amazon Web Services, Nvidia, Service, Home Depot, AWS, VMware, Cloud, Madrona Venture, Amazon, Amazon Web, Annapurna Labs, Intel, AMD Locations: San Francisco, Seattle, Selipsky
Google's cofounder Sergey Brin is back at the search giant — and that includes hyping up its AI work at "TGIF" meetings. Brin appeared onstage during a special 25th-anniversary edition of Google's monthly all-hands meeting (known as "TGIF," or Thank God It's Friday) on September 26. A recording seen by Insider shows Brin receiving rapturous applause from employees. "I didn't want to say anything because I trust Jeff," Brin added. "When we started, it was actually on Fridays and then it made its way to Tuesday," Brin said.
Persons: Sergey Brin, Brin, Larry Page, Sundar Pichai, Google's, Douglas Adams, Jeff Dean, Andrew Ng, Dean, Jeff, " Brin, anyone's Organizations: Google, Street Journal Locations: View , California
Their experience raises broader questions around other high-cost gene therapies coming to market, sometimes after accelerated regulatory approvals, drug pricing experts said. Gene therapies work by replacing genes – the body's blueprint for its development. The gene Zolgensma delivers instructs the body to make a protein vital for muscle control. If gene therapies do fall short, it becomes harder to justify prices that researchers have argued are already poor value. More recently, the first hemophilia gene therapy approved by the U.S. Food and Drug Administration was priced by CSL Behring at $3.5 million; 26 more gene therapies are in late-stage development, according to IQVIA.
Persons: Elizabeth Kutschke, Ben, Zolgensma, Ben Kutschke, neurologists, Sitra Tauscher, Wisniewski, Ben's, Roger Hajjar, Brigham Gene, Kutschke, Vasant Narasimhan, Stacie Dusetzina, Roche's, Biogen, Roche, Maha Radhakrishnan, Steven Pearson, It's, Sree Chaguturu, Amanda Cook, Weston, Jackson, Cook, Elizabeth, Jerry Mendell, Russell Butterfield, , Biogen's, Mendell, UMR, Spinraza, Eric Cox, Caroline Humer, Sara Ledwith Organizations: Reuters, U.S, Novartis, IQVIA Institute, Human Data, Novartis Gene Therapies, Mass, Cell Therapy, U.S . Food, Drug Administration, CSL Behring, CSL, Nashville's Vanderbilt University School of Medicine, Clinical, Economic, CVS Health, Aetna, SMA, Nationwide Children's Hospital, University of Utah Health, Children's, UnitedHealth, Thomson Locations: Oak Park, Berwyn , Illinois, Swiss, U.S, Lebanon , Virginia, United States, Columbus , Ohio, Russia, Kazakhstan, Chicago
To learn more about the neuroscience behind this widespread behavior, he and his colleagues played with and tickled rats and observed the rodents’ brain activity. Researchers studied how playing and being tickled affected rats’ brain activity. Key brain areaTo learn more about how playing and being tickled affect rats’ brain activity, the researchers devised a series of experiments. The researchers played “hand chasing games” with their rat subjects and gently tickled them, while tiny, wireless neural probes recorded the rats’ brain activity. Furthermore, in trials where the scientists inhibited activity in this part of the brain, the rats were less inclined to play or laugh when tickled.
Persons: Michael Brecht, they’re, Brecht, it’s, ” Brecht, , , everyone’s, , one’s, we’ve, Alexa Veenema, Veenema, ” Veenema, Kate Golembiewski Organizations: CNN, Bowl, Humboldt University, Michigan State University Locations: Berlin, Chicago
These Flies Age Faster After Witnessing Death
  + stars: | 2023-06-13 | by ( Darren Incorvaia | ) www.nytimes.com   time to read: +1 min
Dr. Pletcher and Dr. Gendron found that flies that had seen corpses were avoided by other flies, as if they’d been marked by death (how this works is still a mystery). The two scientists housed living flies in vials with fly cadavers for two days, and tracked their brain activity with a fluorescent green dye. Dr. Gendron and Dr. Pletcher then identified the key neurons in the ellipsoid body. When these were shut off, seeing dead flies did nothing to the life span of the living. When the researchers activated those neuron clusters, flies met their maker sooner, even if they had never been exposed to dead flies.
Persons: Gendron, Scott Pletcher, , Pletcher, they’d Organizations: University of Michigan
CNN —It’s an image that encapsulates the power of friendship through adversity: Kevin Sinfield, a legendary figure in the sport of rugby league, stops short of the finish line of a marathon to gather Rob Burrow, his friend and former teammate, into his arms. The poignant moment came at the end of the inaugural Rob Burrow Leeds Marathon on Sunday and the pair received cheers from those spectating when they crossed the line together. Sinfield pushes Burrow during the Rob Burrow Leeds Marathon. The fact that he’s going to be right under my nose this time, I won’t be short of inspiration.”Sinfield kisses Burrow as the pair cross the finish line. He ran Sunday’s marathon in a jersey bearing the number seven, which Burrow wore throughout his rugby career.
F.D.A. Approves New Drug to Treat Hot Flashes
  + stars: | 2023-05-12 | by ( Christina Jewett | ) www.nytimes.com   time to read: +3 min
“Hot flashes as a result of menopause can be a serious physical burden on women and impact their quality of life,” said Dr. Janet Maynard, an official with the F.D.A. Background: Symptoms have long been enduredHot flashes are the most common side effect of menopause for which women typically seek treatment, Astellas said. And the complaints of those who experience severe hot flashes and other symptoms of menopause are often dismissed in the workplace and elsewhere. Because signs of liver damage emerged in some patients during study of the drug, the F.D.A. What’s Next: The drug price may be prohibitiveAstellas said that the drug would cost $550 for a 30-day supply, not including rebates.
The company said that it is collaborating with multiple new energy carmakers in China on developing robotaxis. "We hope they can enter Didi's network and provide services by 2025," Didi Autonomous Driving COO Meng Xing said at a company event that was livestreamed online. He also showed off a robotaxi concept car called "Didi Neuron", with robotic arms that can help passengers pick up luggage. Didi allows users in some parts of Shanghai and the southern city of Guangzhou to hail self-driving cars through its main app. Swedish carmaker Volvo, owned by Geely (GEELY.UL), supplies Didi's self-driving fleet.
HONG KONG, April 13 (Reuters) - Chinese ride-hailing giant Didi Global showed off a robotaxi concept car it called "Didi Neuron" during a company event broadcast online on Thursday, which has robotic arms that can help passengers pick up bottles of water or carry their luggage. The blue and white vehicle was unveiled by Didi Autonomous Driving COO Meng Xing. Reporting by Josh Ye, writing by Brenda Goh; Editing by Bernadette BaumOur Standards: The Thomson Reuters Trust Principles.
Chinese ride-hailing giant DiDi debuted the DiDi Neuron, a concept robotaxi. DiDi is working with Chinese carmakers to develop its own autonomous taxis which it is aiming to put into service in 2025. DiDi Global on Thursday said it is developing its own self-driving taxis alongside Chinese carmakers and it plans to roll them out in 2025 on its ride-hailing service. The Chinese giant's autonomous driving unit also showed off a concept robotaxi, or driverless taxi, called DiDi Neuron. DiDi set up its autonomous driving unit in 2016 and spun it off into a wholly-owned subsidiary in 2019.
U.S. FDA approves Acadia's Rett syndrome drug
  + stars: | 2023-03-14 | by ( ) www.reuters.com   time to read: +3 min
The approval comes months after the FDA declined to approve expanded use of Acadia's drug Nuplazid to treat psychosis related to Alzheimer's disease. Acadia said it plans to make the drug available to patients by the end of April. He forecast peak U.S. trofinetide sales of $487.2 million by 2035. After the FDA declined to approve the expanded use of Nuplazid, Acadia said it would not pursue that indication for Nuplazid further. Improvement of symptoms was measured according to the assessment scales Rett Syndrome Behaviour Questionnaire and the Clinical Global Impression of Improvement.
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