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What If Men Could Make Their Own Egg Cells?
  + stars: | 2023-10-27 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
The Japanese biologist Katsuhiko Hayashi said earlier this year that he believes it will be possible to create a human egg from skin cells within a decade. He and his colleagues have already turned skin cells from male mice into mouse eggs and used them to breed baby mice. Matt Krisiloff , chief executive officer of Conception Biosciences, has dozens of scientists working at a lab in Berkeley, Calif., trying to make eggs outside ovaries. Such a technique could allow women to have biological children later in life.
Persons: Katsuhiko Hayashi, Matt Krisiloff Organizations: Conception Biosciences Locations: Berkeley, Calif
Speaking at a conference, they said they made female eggs from male cells. He then used that technique to make female eggs, called oocytes, from male cells and fertilized them to create seven mice with two biological dads. REUTERS/Alan Trounson/California Institute for Regenerative Medicine/HandoutThey then deleted the Y chromosomes in the cells and duplicated the cells' X chromosomes, before prompting the cells to turn into egg cells with two X chromosomes. The technique could also help women and people with two X chromosomes who have a genetic issue with one of the X chromosomes to have children, he said. Human reproductive cells are very complex and much less well-known than mice cells.
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