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The unanimous vote by the 16 advisers recommends a formula aimed at combating the variant JN.1, which dominated infections in the United States in February, or a version of it. In recent weeks, JN.1 has been overtaken by descendants known as KP.2 and KP.3. is expected to formally recommend a variant target for vaccine makers for the next round of shots in the late summer or early fall. Any decision involves some educated guesswork, given that any new vaccine formula won’t be available until months after a variant becomes dominant. “It’s becoming clear that the ideal timing for a vaccine composition decision remains elusive,” said Jerry Weir, an official with the F.D.A.’s vaccine division.
Persons: , Jerry Weir Organizations: Food and Drug Administration Locations: United States
Starting this fall, however, all the flu shots distributed in the United States will probably contain only three strains, and the change is because of Covid-19. It’s not quick or easy to change how flu vaccines are manufactured, and those changes require regulatory review and approval. The committee is meeting Tuesday to discuss next steps and vote on flu vaccine recommendations for the fall. “Anytime these flu vaccines are being produced, they are – depending on which vaccines you are talking about – using live or attenuated virus, and you do have to grow it,” she said. But as the authors note, any such change would require testing and regulatory approval, and for that reason, it’s not likely we’ll see the return of four-strain flu shots any time soon.
Persons: Covid, Yamagata, It’s, We’ve, , Paul Offit, Offit, Jodie Guest, Dr, Sanjay Gupta, Arnold Monto, Maria Zambon, Jerry Weir, it’s Organizations: CNN, World Health Organization, Food and Drug Administration, Vaccine Education, Children’s Hospital of Philadelphia, Biological Products Advisory, WHO, Emory University’s Rollins School of Public Health, Get CNN, CNN Health, New England, of Medicine, UK Health Security Agency Locations: United States, Victoria, Yamagata
An advisory committee to the Food and Drug Administration on Thursday raised doubts about shifting toward a yearly Covid booster for most adults and children, saying too many questions about the virus still remain unanswered. The FDA convened its Vaccine and Related Biology Products Advisory Committee to discuss how the Covid vaccines may change moving forward. On Monday, the agency published briefing documents proposing annual Covid shots that target the latest variants of the virus — an approach similar to the yearly flu shot. Some committee members said they would prefer to make multiple yearly meetings on the Covid vaccines the norm. In a unanimous vote, the committee recommended using the bivalent formula in all Covid vaccines moving forward, not just for booster shots.
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