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Why don’t humans have tails?
  + stars: | 2024-03-23 | by ( Mindy Weisberger | ) edition.cnn.com   time to read: +10 min
One of those led to shorter tails; the more of that protein the genes produced, the shorter the tails. A tail as old as timeFor modern humans, tails are a distant genetic memory. While Alu’s role “seems to be a very important one,” other genetic factors likely contributed to the permanent disappearance of our primate ancestors’ tails,” Xia said. In their experiments, the researchers found that when mice were genetically engineered for tail loss, some developed neural tube deformities that resembled spina bifida in humans. “Maybe the reason why we have this condition in humans is because of this trade-off that our ancestors made 25 million years ago to lose their tails,” Yanai said.
Persons: , Alu, AluY, Bo Xia, ” Xia, , Xia, Itai Yanai, ” Yanai, , Bo, Yanai, TBXT’s, Liza Shapiro, ” Shapiro, africanus, Shapiro, spina, Mindy Weisberger Organizations: CNN, Gene, Broad Institute of MIT, Harvard University, Institute for Systems Genetics, New York University Grossman School of Medicine, University of Texas, Scientific Locations: Austin, Kenya
A single genetic tweak that occurred among our ancestors 25 million years ago means humans today are unable to grow a tail, according to a new study. Scientists knew that a gene called TBXT was involved in the snipping of the tail. Asep Supriatna/Getty ImagesWandering DNA snipped off our tailsThe solution, they found, was in a type of "jumping gene" called an Alu element. Scientists found two Alu elements around a part of the TBXT gene, called Exon 6. Scientists tested their findings by inserting Alu sequences in mice.
Persons: , Himanshu Sharma, it's, we've, Asep Supriatna, Miriam Konkel, Emily Casanova, Konkel, Casanova Organizations: Service, Business, Anadolu Agency, Getty, NYU, Grossman School of Medicine, Nature, NYU Grossman School of Medicine, Science Locations: Pushkar, Rajasthan, India
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