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Additional lab and animal research presented in both papers revealed erythritol and xylitol may cause blood platelets to clot more readily. Clots can break off and travel to the heart, triggering a heart attack, or to the brain, triggering a stroke. “It’s sold as a so-called natural sweetener, and because xylitol doesn’t spike blood sugar levels, it’s also marketed as low carb and keto friendly,” Hazen said. The February 2023 erythritol in study found the risk of heart attack and stroke nearly doubled within three years when people had the highest levels of erythritol in their blood. For the new study on xylitol, the results were basically the same — people with the highest levels of xylitol compared to those with the lowest levels had nearly twice the risk of heart attack, stroke and death, Hazen said.
Persons: , , Stanley Hazen, Hazen, erythritol, Matthew Tomey, Tomey, Andrew Freeman, Freeman, xylitol, It’s, ” Hazen, you’re, Erythritol, Sinai’s Tomey Organizations: CNN, Center for Cardiovascular Diagnostics, Cleveland Clinic Lerner Research Institute, Cleveland Clinic’s Center, Human, Icahn School of Medicine, American Heart Association, Jewish Health, Getty, Food and Drug Administration, Heart Journal, World Health Organization Locations: stevia, Mount, New York City, Mount Sinai, Denver
Bederson, system chair for the Department of Neurosurgery at Mount Sinai Health System, is no stranger to long hours in an operating room. In fact, it marked the 14th time that the company has placed its array on a human patient's brain. Four of Precision's arrays were carefully laid out on a table nearby. Using a pair of yellow tweezers called long bayonet forceps, Bederson began placing all four of Precision's electrode arrays onto the patient's brain. Real-time renderings of the patient's brain activity swept across Precision's monitors in the operating room.
Persons: Joshua Bederson, Ashley Capoot, Bederson, Elon Musk, Stephanie Rider, Ignacio Saez, Saez, Bederson's, Benjamin Rapoport, Precision's, Ashley Capoot Bederson, Precision's Rapoport, Rapoport, Ashley Capoot Rapoport, Thomas Oxley, Synchron Organizations: Sinai, Neurosurgery, Sinai Health, CNBC, Neuroscience, BCI, Tesla, SpaceX, Icahn School of Medicine, U.S . Food, Drug Administration, Mount, Mount Sinai, Precision Neuroscience, Weill Cornell Medicine, Wall Locations: New York City, Mount Sinai, U.S, Mount, Synchron
CNN —Chemical toxins are everywhere — in our water, food, air and soil. Children born to European mothers exposed to four families of chemicals that disrupt the body’s endocrine (hormone) system had elevated levels of metabolic syndrome at ages 6 to 11. Metabolic syndrome can include obesity, elevated blood pressure, and abnormally high cholesterol and insulin resistance, which is a precursor to type 2 diabetes. Metabolic syndrome is typically associated with adult cardiovascular disease, type 2 diabetes and stroke, but the growing epidemic of childhood obesity has seen symptoms appearing in kids at younger and younger ages. Having metabolic syndrome as a child is highly predictive of chronic disease as an adult, experts say.
Persons: Nuria Güil, , Oumrait, Vicente Mustieles, Mariana Fernández, Carmen Messerlian, Messerlian, phthalates, , Jane Houlihan, ” Houlihan, Houlihan, PFAS, EWG Organizations: CNN, Icahn School of Medicine, JAMA, Biomedical Research, University of Granada, Harvard, of Public Health, International Council for Chemical Associations, American Chemistry Council, EPA, Food, Food and Drug Administration, FDA, NSF, National Sanitation Foundation Locations: Mount Sinai, New York City, Spain, Messerlian, Chan, Boston, United States
Opinion | The Language of Gender Identity
  + stars: | 2024-04-17 | by ( ) www.nytimes.com   time to read: +1 min
To the Editor:Re “The Problem With Saying ‘Sex Assigned at Birth,’” by Alex Byrne and Carole K. Hooven (Opinion guest essay, nytimes.com, April 3):Mr. Byrne and Ms. Hooven argue that use of “assigned sex” terminology “creates doubt about a biological fact when there shouldn’t be any.” But sex characteristics are not “a biological fact”; they are rather a series of facts — anatomical, hormonal and genetic — that are not always in alignment. The term “sex assignment” derives from the medical literature of the 1940s and 1950s, in which physicians grappled with what was then called “hermaphroditism” and is now called “intersex” or “D.S.D.,” for disorders or differences of sex development. To conclude that the words “assigned at birth” are needless is to deny the complexity of biological sex and to erase both the history of intersex conditions and the embodied reality of the people who are born and live with them. Barbara M. ChubakNew YorkThe writer is an associate professor of urology at the Icahn School of Medicine at Mount Sinai.
Persons: Alex Byrne, Carole K, Byrne, Hooven, Barbara M, Chubak Organizations: Icahn School of Medicine Locations: York, Mount Sinai
CNN —Pregnancy complications, such as gestational diabetes or preeclampsia, may be linked to an elevated risk of death even decades after giving birth, according to a new study. The study, published Monday in the journal JAMA Internal Medicine, found that women who experienced major complications during pregnancy had an increased risk of early death and that risk remained elevated for more than 40 years. The data showed that more than 88,000 women had died and all five pregnancy complications were independently associated with a higher mortality risk later in life. Gestational diabetes was associated with a 52% increased risk of mortality, preterm delivery was associated with a 41% increased risk, delivering a baby with low birth weight was associated with a 30% increased risk, preeclampsia with a 13% increased risk and other hypertensive disorders with a 27% increased risk, the data showed. “We found that the increased mortality was attributable to multiple different causes of death, including heart disease, diabetes, respiratory disorders, and cancer,” he said.
Persons: Dr, Casey Crump, ” Crump, , , Ashley Roman, ” Roman, Crump, Joanne Stone, Raquel, Jaime Gilinski, ” Stone, Sanjay Gupta Organizations: CNN, The University of Texas Health Science Center, Lund University, NYU Langone Health, , of Obstetrics, Icahn School of Medicine, CNN Health Locations: UTHealth, Houston, Malmö, Sweden, United States, Mount
One in four American households has a member who experiences migraine, according to the American Migraine Foundation. "I get asked all the time about a migraine diet, [and] there is no one true migraine diet," that can prevent symptoms, says Dr. Fred Cohen, headache specialist and assistant professor of medicine and neurology at the Icahn School of Medicine at Mount Sinai. But "certain foods can trigger [migraine]," and make symptoms worse, Cohen adds. Here are some foods that migraineurs, people who frequently get migraine headaches, have reported as triggers for migraine attacks.
Persons: Fred Cohen, Cohen Organizations: Icahn School of Medicine Locations: Mount Sinai
More than 10% of people worldwide, especially between the ages of 20 and 50, experience migraine, according to The Journal of the American Medical Association. Symptoms of migraine are worse than a typical headache, and moderate to severe headaches are only one of the symptoms of migraine, Cohen tells CNBC Make It. Additional symptoms of migraine can be:NauseaVomitingPhotophobia, a sensitivity to lightPhonophobia, a sensitivity to soundThere isn't a singular cause of migraine, Cohen says. For some people, migraine is genetic and runs in their family; for others, lifestyle choices like diet, stress and even weather changes can trigger migraine symptoms. Thankfully, debilitating symptoms of migraine can be relieved with some natural remedies.
Persons: Fred Cohen, Cohen Organizations: American Medical Association, Icahn School of Medicine, CNBC Locations: U.S, Mount Sinai
Read previewAxel Bouchon cofounded Matter Neuroscience in 2019 after leading the venture arms of pharma giants Moderna and Bayer. AdvertisementMatter has emerged from stealth with $26 million from ARCH Venture Partners, Polaris Partners, Exor Ventures, and Collaborative Fund, Business Insider has learned exclusively. That $26 million includes an initial seed round led by Polaris Partners and a Series A round led by ARCH Venture Partners. The startup views itself now as a consumer biotech startup, Bouchon said. Here's the 17-slide pitch deck Matter used to raise $26 million.
Persons: , Axel Bouchon, Bouchon Organizations: Service, pharma, Moderna, Bayer, Business, Venture Partners, Polaris Partners, Exor Ventures, Fund, Brain Imaging, Icahn School of Medicine Locations: Maastricht, Netherlands, Mount Sinai, Seoul, South Korea
These genetic variants may have subsequently proved beneficial to European populations in making the shift from hunting and gathering to farming. “DNA from hunter-gatherers is present at higher levels in Northeastern Europe, which means the region has an elevated genetic risk of developing Alzheimer’s disease,” Barrie said. Similarly, the ancient genetic information shed light on the evolutionary history of traits such as height and lactose tolerance. And for most traits, MS included, the genetic effects are the result of multiple genetic variants,” he said. “Ultimately, we can’t say that MS came from Bronze Age populations, but these populations’ movements and environments contribute to differences in MS risk today.”
Persons: , , Rasmus Nielsen, It’s, William Barrie, Astrid Iversen, ” Iversen, ε4, ” Barrie, Samira, Asgari, Tony Capra, Capra, wasn’t Organizations: CNN —, University of California, Danish National, University of Cambridge’s, University of Oxford, Icahn School of Medicine, Bakar Computational Health Sciences Institute Locations: Western Europe, Central Asia, Europe, Berkeley, Kazakhstan, Northeastern Europe, Mount Sinai, New York, Bakar, San Francisco
Sarah Gundle Sarah Gundle, PsyDThese are appropriate questions, when you consider the public fascination with stories about Gypsy Rose Blanchard, who was recently released on parole after serving eight and a half years for helping to kill her abusive mother. The revelation drove Gypsy Rose to seek revenge by convincing her boyfriend to murder her mother. Of course, the behavior of Dee Dee Blanchard and Debra McCurdy was beyond the pale, rising to the level of evil. And would Dee Dee Blanchard have been able to stop the train of destruction if someone had more doggedly recognized and confronted her mental illness? Maybe we need to heed the words of Gypsy Rose Blanchard, who has said that trying to understand where her mother was coming from “brought me to a place of forgiveness.” Blanchard recently told CNN of her mother: “She was not an evil woman.
Persons: Sarah Gundle, Sarah Gundle Sarah Gundle, Gypsy Rose Blanchard, Gypsy Rose Blanchard ”, Blanchard, Claudine “ Dee Dee ” Blanchard, Gypsy Rose, Dee Dee, , Jennette McCurdy, McCurdy, , Debra, Dee Dee Blanchard, Debra McCurdy, , I’m, ” Andrew Solomon, Rozsika Parker, “ We’re, that’s, Carl Jung, don’t, Dee Dee Blanchards, Debra McCurdys, ” Blanchard, Organizations: Icahn School of Medicine, Mount Sinai Medical, CNN, Nickelodeon Locations: New York City
Decades of treatment of military veterans and sexual assault survivors have left little doubt that traumatic memories function differently from other memories. The team conducted brain scans of 28 people with PTSD while they listened to recorded narrations of their own memories. Some of the recorded memories were neutral, some were simply “sad,” and some were traumatic. The brain scans found clear differences, the researchers reported in a paper published on Thursday in the journal Nature Neuroscience. The people listening to the sad memories, which often involved the death of a family member, showed consistently high engagement of the hippocampus, part of the brain that organizes and contextualizes memories.
Organizations: Yale University, Icahn School of Medicine, Mount, Neuroscience
For years, medical professionals widely recommended regular aspirin to prevent heart problems, since aspirin can reduce blood clotting to prevent complications like heart attacks or strokes. Still, many health care professionals still consider aspirin to be beneficial for many patients who have heart problems or have a stent. Dropping aspirin also reduced the risk of severe bleeding by nearly 50% compared with patients on the combination therapy, said Mehran — without increasing the risk of cardiac complications. Given the results of her clinical trial and a growing amount of evidence suggesting that long-term aspirin may not be beneficial for acute coronary syndrome, Mehran prescribes a treatment plan without long-term aspirin for her own patients. Aspirin remains ‘an essential therapy’However, experts agree that aspirin remains a beneficial medication for heart conditions.
Persons: ’ ”, Roxana Mehran, Mehran, ” Mehran, Aspirin, Dr, Harlan Krumholz, ticagrelor, Sanjay Gupta, Organizations: CNN, Icahn School of Medicine, World Health Organization, American College of Cardiology, American Heart Association, United States Preventive Services Task Force, Yale School of Medicine, CNN Health Locations: Mount Sinai, United States, South Korea
Tsai predicts that AI will one day help doctors analyze complicated genetic data — a hallmark of precision medicine. Together, AI imaging and genetic analysis may help doctors rapidly pinpoint a diagnosis and create a highly personalized treatment plan, thus improving a patient's care. AI and the potential for genetic analysisIn addition to medical imaging, AI could one day comb through large amounts of genetic information, a challenging task for researchers. A possible convergence in the clinicWang does not see combining AI imaging and AI genetic analysis at the doctor's office happening within the next couple of years. Chang and his colleagues are investigating how AI analysis of brain scans can predict genetic mutations in brain tumors.
Persons: James C, Tsai, Peter D, Chang, Zhenghe J, Wang Organizations: Healthcare, Morning, Center, Ophthalmic Artificial Intelligence, Human, Icahn School of Medicine, US Food and Drug Administration, Applied, Research, University of California, Case Western Reserve University Locations: Mount, Irvine
The conflict in Israel and Gaza has dominated the news cycle for the last week. Turn on the TV or log on to any social media platform and you'll be confronted with a barrage of horrific headlines. While staying informed is important, consuming an excess of graphic images and videos can negatively affect your mental health. "Nothing good" happens to your brain when you see violent images, says Iliyan Ivanov, a professor of psychiatry at the Icahn School of Medicine at Mount Sinai. There are ways, though, to consume the news and still take care of your mental health.
Persons: Iliyan Ivanov Organizations: Media, Icahn School of Medicine, CNBC Locations: Israel, Gaza, Mount Sinai
How to Take Care of Your Skin in the Fall and Winter
  + stars: | 2023-09-25 | by ( Anna Maltby | ) www.nytimes.com   time to read: +1 min
As the outside air cools and the heat starts to crank on indoors, you may notice your skin becoming flaky, maybe even a bit itchy. Welcome to fall and winter. When temperatures drop, the air gets drier — both indoors and outdoors — and moisture gets pulled from the lipid barrier. With less hydration, the turnover of skin cells is impaired and they start to clump together, which people can experience as dry, flaky or even scaly skin, Dr. Craiglow said. Some are more susceptible to developing dry skin in cooler weather, particularly older adults and those with eczema, said Dr. Jeffrey Weinberg, a clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai.
Persons: , Brittany Craiglow, Craiglow, Jeffrey Weinberg Organizations: Yale School of Medicine, Icahn School of Medicine Locations: Fairfield , Conn, Mount Sinai
A good treatment option for indigestion may already be in your spice rack, according to a new study. Researchers found no significant differences in the symptoms of the groups taking the drug, turmeric or the combination of the two, according to the study. Turmeric has been used by people in Southeast Asia to treat stomach discomfort and other inflammatory conditions, Pongpirul said. That said, curcumin and turmeric is “generally considered safe when consumed in the amounts typically found in food,” he added. Typically, turmeric spices contain around 3% curcumin, according to the National Library of Medicine.
Persons: , Krit Pongpirul, Pongpirul, Pongpoirul, Yuying Luo, curcumin, Luo, , , ” Pongpuri, Pongpuri Organizations: CNN, Mayo Clinic, Chulalongkorn University, National Library of Medicine, gastroenterology, Icahn School of Medicine Locations: Bangkok, Thailand, Southeast Asia, United States, dyspepsia, Mount Sinai, New York City
CNN —Scientists have grown kidneys containing mostly human cells inside pig embryos, an important step toward growing kidneys and potentially other human organs that could be used for transplants in people. “The paper describes pioneering steps in a new approach to organ bioengineering using pigs as incubators for growing and cultivating human organs,” said Dusko Ilic, a professor of stem cell sciences at King’s College London, in a statement. “It is remarkable to see about 60% of the primordial pig kidney contained human cells,” Wu said. What the researchers didTo generate kidneys mostly composed of human cells in pigs, the scientists used cutting-edge techniques harnessing advances in stem cells, gene editing and embryology. “This (new) work is different from existing xenotransplantation approach and aims to generate organs mostly composed of human cells in pigs,” Wu said.
Persons: , Miguel Esteban, ” Esteban, , Dusko Ilic, Jun Wu, Wu, ” Mary Garry, ” Wu, Esteban, ” Joseph A, Vassalotti, ” Vassalotti Organizations: CNN —, Guangzhou Institute of Biomedicine, Chinese Academy of Sciences, Procurement, Transplantation Network, King’s College London, University of Texas Southwestern Medical Center, University of Minnesota’s, Heart Institute, National Kidney Foundation, Icahn School of Medicine Locations: Health, United States, Mount Sinai
A new study suggests human ancestors nearly went extinct some 930,000 years ago. Scientists in China used modern human genomes to estimate what past populations may have looked like. It turns out our human ancestors may have faced a near miss that could have changed everything. Scientists in China last week released the results of a study that used current human genomes to make predictions about populations in the past. They found that something — perhaps an ancient climate crisis, they suggest — caused the population of human ancestors to drop drastically.
Persons: , Wangjie Hu, Nick Ashton Organizations: Service, Scientists, Icahn, of Medicine, New York Times, Africa —, Times Locations: China, Wall, Silicon, New, Mount, Africa, , Europe, Asia
'Barbie Botox' goes viral but doctors inject caution
  + stars: | 2023-09-01 | by ( Leroy Leo | ) www.reuters.com   time to read: +4 min
But since the "Barbie" movie released in July, there has been an uptick in demand for use as a cosmetic procedure. Meanwhile, Revance and Evolus Inc (EOLS.O), which make similar toxins under the brand Daxxify and Jeuveau, respectively, told Reuters that though "Barbie Botox" has picked up in recent months, they do not see the trend significantly boosting sales. However, the doctors said they were concerned about a rise in use among younger women - and six doctors warned that procedures by underqualified staff at some medispas raised the risk of complications. Doctors also stressed the risk with administration by people who may not be properly qualified, especially at medispas where there is little oversight. "The science isn't quite there yet, in order to support the clinical profile of it," said Evolus CEO David Moatazedi.
Persons: Margot Robbie, BarbieBotox, that's, Barbie, Dustin Sjuts, Scot Glasberg, Revance, Shilpi Kheterpal, Kheterpal, Doctors, Melissa Levoska, David Moatazedi, Leroy Leo, Sriraj Organizations: Therapeutics, Reuters, Plastic Surgery Foundation, U.S . Food, Drug Administration, Evolus Inc, AbbVie Inc, Cleveland Clinic, Icahn School of Medicine, Thomson Locations: New York, U.S, medispas, Mount Sinai, Bengaluru
[1/2] A selection of injector pens for the Wegovy weight loss drug are shown in this photo illustration in Chicago, Illinois, U.S., March 31, 2023. The global market for weight-loss drugs is forecast to reach as much as $100 billion within the decade. Beyond severe mental health disorders, other patients struggling with obesity tend to suffer from mental health issues like depression and anxiety at higher levels than the general population, studies show. However, psychiatrists specializing in eating disorders are wary that drugs like Wegovy could exacerbate their patients’ focus on weight loss because they are so effective. Dr. Michael Weintraub, an endocrinologist at NYU Langone Health, said ideally psychiatrists will work with endocrinologists because weight-loss drugs require careful monitoring not related to mental health issues.
Persons: Jim Vondruska, Wegovy, Novo, It's, doggedly, Joseph Goldberg, Eli Lilly, Natalia Salomao, Dost Ongur, Brigham, Roy Chengappa, New Yorker Alexander Roger, Roger, Michael Weintraub, McLean's Ongur, Elissa Welle, Michele Gershberg, Bill Berkrot Organizations: REUTERS, Icahn School of Medicine, U.S . Food, Drug Administration, Reuters, Mass, Brigham McLean Hospital, University of Pittsburgh Medical Center, New Yorker, Fordham University, Nordisk, NYU Langone Health, Thomson Locations: Chicago , Illinois, U.S, Mount Sinai, New York, Europe, Danish, Boston
CNN —Actor Mandy Moore’s son recently woke up to a startling rash covering his body, according to her Instagram posts. Gianotti-Crosti syndrome. What is Gianotti-Crosti syndrome? Experts say they don’t know why some children get Gianotti-Crosti syndrome and others don’t, but it is thought to be a hypersensitive response to an underlying infection, according to the National Institutes of Health. Usually, the Gianotti-Crosti syndrome resolves itself over time — anywhere from a couple weeks to a couple of months, Levoska said.
Persons: Mandy Moore’s, ” Moore, Melissa Levoska, Shari Lipner, Levoska, Epstein, Barr, , ” Levoska, Lipner, Dermatologists, , it’s Organizations: CNN, Icahn School of Medicine, Weill Cornell Graduate School of Medical Sciences, National Institutes of Health, National Hospital Locations: Instagram, Mount Sinai, New York City, United States, Washington ,
What to Know About Eclampsia
  + stars: | 2023-06-13 | by ( Alisha Haridasani Gupta | ) www.nytimes.com   time to read: +1 min
The report identified complications of childbirth as the cause of death, listing eclampsia and respiratory distress as possible factors. “Eclampsia occurs in somewhere between one to 10 in 10,000 pregnancies,” said Dr. Joanne Stone, the head of the department of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai. Research has suggested that rates of hypertensive disorders of pregnancy — including pre-eclampsia, eclampsia and gestational hypertension — have been on the rise, and increased during the Covid-19 pandemic. What is eclampsia? There can be other causes of seizures during pregnancy, but it’s considered eclampsia “until proven otherwise” through lab tests, including neurological tests, Dr. Longo said.
Persons: Tori Bowie, , Joanne Stone, Monica Longo, Eunice Kennedy, Stone, it’s, Longo Organizations: The New York Times, Olympic, Icahn School of Medicine, Research, National, of Child Health, Human, National Institutes of Health Locations: Mount Sinai
Red light therapy: How it affects sleep
  + stars: | 2023-06-01 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +7 min
CNN —Red light therapy has been found to be helpful for skin health, wound healing, hair growth among people with alopecia and pain management. “That’s why when we talk about blue light or red light, we’re not talking about a red-colored light bulb. A 2019 study led by Figueiro looked into whether delivering red light to closed eyes during sleep — using a red light mask — and to open eyes upon waking — via red light goggles — reduced sleep inertia among 30 adults. In other words, it might be that any benefits come from replacing the light you’re exposed to before sleep with red light, rather than adding the latter during sleep. The bottom line is that when it comes to sleep, “what’s better than red light is no light,” Dasgupta said.
Persons: , Raj Dasgupta, , ” Dasgupta, , Dasgupta, Joshua Tal, Mariana Figueiro, Figueiro, who’s, ” Figueiro Organizations: CNN, US Centers for Disease Control, University of Southern California’s Keck School of Medicine, Mount Sinai, Health Research Center, Icahn School of Medicine Locations: China, New York City, Mount Sinai
CNN —The office of Sen. Dianne Feinstein, the 89-year-old California Democrat who was diagnosed with shingles in February, confirmed Thursday she “continues to have complications” from a viral infection called Ramsay Hunt syndrome. “This makes its true frequency more difficult to determine,” the Cleveland Clinic noted. Ramsay Hunt syndrome can also cause hearing loss on the side of the face affected. About 70% of people with Ramsay Hunt will regain complete or “almost complete” function of facial muscles, according to the Cleveland Clinic. Early diagnosis and prompt treatment with antiviral therapy seem to improve long-term outcomes,” the Cleveland Clinic notes on its website.
Bill Gates' eldest daughter, Jennifer Gates, might now be calling a $51 million New York City penthouse home. 443 Greenwich Street is known for being home to other celebrities like Meg Ryan, and Blake Lively and Ryan Reynold. The penthouse apartment is 8,900 square feet and has a 3,400 square-foot outdoor space with a plunge pool. Gates' penthouse apartment is 8,900 square feet and has a 3,400 square-foot outdoor space. 443 Greenwich Street was designed with an indoor courtyard, which is rare for buildings in New York City.
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