1 most expensive city to be happy in the U.S.: Santa BarbaraSanta Barbara, California is the most expensive U.S. city to be happy. Santa Barbara is also within the Santa Maria-Santa Barbara region, which was named one of the happiest places in the world based on The Blue Zones Index. Honolulu, Hawaii is the second most expensive city to be happy in the U.S. M Swiet Productions | Getty Images10 most expensive cities to be happy in the U.S.Santa Barbara, Calif. Honolulu, Hawaii New York, N.Y. San Francisco, Calif. Seattle, Wash. Oakland, Calif. Anchorage, Alas. Irvine, Calif. Honolulu, Hawaii, ranks as the second most expensive city in the U.S. to be happy in. 3 most expensive city to be happy in the U.S. Bamsgirl411 / 500Px | 500Px | Getty Images

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Persons: Barbara Santa, Santa Barbara Organizations: Purdue University, Economic Research Institute, Santa Barbara, Swiet, Getty Locations: U.S, Australian, Barbara Santa Barbara , California, Santa Barbara, Santa, Santa Maria, Honolulu, Hawaii, Calif, Hawaii New York, N.Y, San Francisco, Seattle, Wash . Oakland, Anchorage, Alas . Sacramento, Boston, Mass, Irvine, The Hawaii, Oahu, Pearl Harbor . New York City