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Veterinary laboratories in several states are investigating an unusual respiratory illness in dogs, and encouraging people to take basic precautions to keep their pets healthy as veterinarians try to pin down what's making the animals sick. Oregon, Colorado and New Hampshire are among the states that have seen cases of the illness, which has caused lasting respiratory disease and pneumonia and does not respond to antibiotics. Symptoms of respiratory illness in dogs include coughing, sneezing, nasal or eye discharge and lethargy. Some cases of the pneunomia progress quickly, making dogs very sick within 24 to 36 hours. Dogs have died, said Kurt Williams, director of the Oregon Veterinary Diagnostic Laboratory at Oregon State University.

Persons: Kurt Williams, Williams, David Needle, Robert Wood Johnson Organizations: Oregon Department of Agriculture, U.S . Department of, National Veterinary Services Laboratory, Oregon Veterinary Diagnostic, Oregon State University, University of New, Diagnostic, Hubbard, for Genome Research, Associated Press Health, Science Department, Robert Wood Johnson Foundation, AP Locations: Oregon , Colorado, New Hampshire, Oregon, University of New Hampshire's New Hampshire, Rhode Island , New Hampshire, Massachusetts

☆ Scientists recover RNA from an extinct species for the first time
▼ + stars: | 2023-09-19 | by ( Katie Hunt | ) edition.cnn.com time to read: +4 min

CNN —Geneticists have for the first time isolated and decoded RNA molecules from a creature that died out long ago. “This will add significant depth to our understanding of the biology of extinct animals and help us to build much better extinct genomes,” he added. Mármol Sánchez said this study is a proof of concept, and his colleagues now hopes to recover RNA from animals that died out much longer ago, such as the woolly mammoth. Recipe bookThe research team was able to sequence RNA of the skin and skeletal muscle tissues from the specimen and identify thylacine-specific genes. Understanding RNA allows scientists to put together a more complete picture of an animal’s biology, Mármol Sánchez said.

Persons: ”, Emilio Mármol Sánchez, Benjamin, Mármol Sánchez, Andrew Pask, “, Pask, that’s Organizations: CNN, Swedish Museum of, Stockholm —, Genome Research, Palaeogenetics, Beaumaris, University of Melbourne Locations: Stockholm, SciLifeLab, Sweden, Tasmania, Hobart , Tasmania, Australia

☆ In a first, RNA is recovered from extinct Tasmanian tiger
▼ + stars: | 2023-09-19 | by ( Will Dunham | ) www.reuters.com time to read: +4 min

But this study marked the first time that RNA - much less stable than DNA - has been recovered from an extinct species. While not the focus of this research, the ability to extract, sequence and analyze old RNA could boost efforts by other scientists toward recreating extinct species. The Tasmanian tiger resembled a wolf, aside from the tiger-like stripes on its back. The last-known Tasmanian tiger succumbed in a Tasmanian zoo in 1936. Private "de-extinction" initiatives have been launched aimed at resurrecting certain extinct species such as the Tasmanian tiger, dodo or woolly mammoth.

Persons: Emilio Marmol Sanchez, Handout, bioinformatician Emilio Mármol Sánchez, Marc Friedländer, Love, Mármol, Will Dunham, Rosalba O'Brien Organizations: Swedish Museum of, REUTERS Acquire, Tasmanian, Palaeogenetics, Genome Research, Stockholm University, SciLifeLab, Thomson Locations: Stockholm, SciLifeLab, Sweden, Australia, Tasmania, Tasmanian, Washington

☆ Scientists fully sequence human Y chromosome for the first time
▼ + stars: | 2023-08-25 | by ( Katie Hunt | ) edition.cnn.com time to read: +7 min

However, over half of the sequences within the Y chromosome, the smallest and most complicated of the 46 human chromosomes, remained unknown. Now, the same group of researchers has filled in the missing information, publishing a complete Y chromosome sequence Wednesday in the journal Nature. “This new analysis will allow us to better understand the regions of the Y chromosome that have regulatory functions and may encode mRNA and proteins.”Many people begin to lose their Y chromosome in some of their cells as they age, particularly those cells that undergo rapid turnover, such as blood cells. Having a complete Y chromosome genetic reference may help scientists and doctors further explore this potential link. “However, it has been questioned whether loss of the Y chromosome is a biomarker of biological aging or whether loss of the Y chromosome has a direct effect on the health of men,” he said.

Persons: ”, Monika Cechova, Cechova, Kenneth Walsh, ” Walsh, Walsh, it’s, ” Cechova, Charles Lee Organizations: CNN —, University of California, University of Virginia School of Medicine, Human Genome Research, T2T Consortium, Jackson Laboratory, Genomic Medicine Locations: Santa Cruz

☆ Scientists have completely sequenced the human Y chromosome for the first time, with huge implications for heath and evolution research
▼ + stars: | 2023-08-24 | by ( Jenny Mcgrath | ) www.businessinsider.com time to read: +7 min

Researchers published two new papers on the human Y chromosome. That's because the Y chromosome is "the most complex, most repetitive chromosome," said Monika Cechova, a postdoctoral researcher at the University of California, Santa Cruz. AdvertisementAdvertisementKaren Miga was one of the researchers involved in fully sequencing the human Y chromosome. The worldwide Y chromosomeFor the single-sequence paper, researchers sequenced the Y chromosome of a single individual of European descent, known as the HG002 genome. Because of all the gaps in the Y chromosome genome reference, researchers haven't fully understood how the chromosome contributes to overall health.

Persons: Karen Miga, Monika Cechova, Carolyn Lagattuta, Pascal Gagneux, wasn't, Gagneaux, Evan Eichler, Cechova, Miga, Gagneux, haven't Organizations: Service, Telomere, University of California, UC Santa Cruz, UC San Diego, Center for Academic Research, Human Genome Research Institute, Jackson Laboratory, Genomic Medicine Locations: Wall, Silicon, Nature, Santa Cruz, Anthropogeny

☆ Scientists solve the genetic puzzle of sex-related Y chromosome
▼ + stars: | 2023-08-23 | by ( Will Dunham | ) www.reuters.com time to read: +4 min

Males possess one Y and one X chromosome while females have two X chromosomes, with some exceptions. But until now, the Y chromosome part of the human genome had contained big gaps. In addition to identifying some additional Y chromosome genes, the researchers found that some DNA from the chromosome had been mistaken in previous studies as bacterial in nature. The first complete human genome - albeit with the Y chromosome partial - was published last year. Fully sequencing the Y chromosome adds to this.

Persons: Karen Miga, Carolyn Lagattuta, Arang Rhie, Monika Cechova, Cechova, Will Dunham, Rosalba O'Brien Organizations: University of California, UC Santa Cruz, REUTERS, Rights, Wednesday, U.S ., Genome Research, of California, UCSC, Thomson Locations: Santa Cruz , California, U.S, Handout, Santa Cruz

☆ Human genome reboot better reflects global population
▼ + stars: | 2023-05-10 | by ( Will Dunham | ) www.reuters.com time to read: +5 min

The new genome rundown may help clarify the contribution of genetic variation to health and disease, improve genetic testing, and guide drug discovery. "A pangenome is not just one reference genome, but a whole collection of diverse genomes. Researchers in 2003 unveiled what was billed as the complete sequence of the human genome, though about 8% of it had not been fully deciphered. That reference genome was a mosaic drawn from about 20 people, including 70% from one individual of mixed European and African ancestry. The first complete human genome, based on a single European individual, was published last year after scientists filled in the gaps.

☆ Scientists updated the human genome to make it more inclusive
▼ + stars: | 2023-05-10 | by ( Katie Hunt | ) edition.cnn.com time to read: +6 min

CNN —Scientists have pieced together a new draft of the human genome that better captures humanity’s genetic diversity. The scientists involved say it will improve our ability to diagnose disease, discover new drugs and understand the genetic variants that lead to ill health or a particular physical trait. The pangenome, a digital amalgamation of sequences that can be used to compare, construct and study other human genome sequences, is still a draft. The first draft of the human genome was released in 2001 and was only fully completed in 2022. The new pangenome reference is an amalgamation of different genomes from 47 people with ancestry from around the world.

☆ Fact Check-No evidence ‘RNA technology’ in chicken feed behind infertility or U.S. egg shortage
▼ + stars: | 2023-02-07 | by ( Reuters Fact Check | ) www.reuters.com time to read: +4 min

Some posts also reference studies unrelated to the contents of chicken feed, to chicken fertility or to RNA to imply that a feed additive is behind egg shortages and increased prices. One post says, “RNA technology in chicken feed causing chickens to stop laying“ and can be seen (here) . There is also no evidence of alleged additives in chicken feed affecting the laying habits of chickens. “Also, there is no such thing as adding RNA to chicken feed,” Abasht said. There is no evidence that “RNA technology” is present in chicken feed, or causing infertility in chickens or involved in the current egg shortage in the United StatesThis article was produced by the Reuters Fact Check team.

☆ Fact Check-COVID-19 vaccines do not add a ‘third strand’ of DNA
▼ + stars: | 2023-02-02 | by ( Reuters Fact Check | ) www.reuters.com time to read: +4 min

Moderna’s mRNA COVID-19 vaccine does not alter human DNA or add a third strand to people’s DNA, as claimed in a video circulating on social media and viewed more than 400,000 times on Twitter. This gave me chills.”However, the video offers no evidence for its claim about the vaccine altering human DNA. The messenger RNA (mRNA) in approved COVID-19 vaccines does not interact with human DNA inside cells, and does not enter the cell nucleus where DNA is housed. Reuters has also addressed other false claims that mRNA vaccines alter human DNA (here, here, here). COVID-19 vaccines based on mRNA do not alter human DNA or add a third strand to the DNA double helix.

☆ Fact Check-PCR test for COVID-19 uses gene cloning but cannot be used to clone humans
▼ + stars: | 2022-11-29 | by ( Reuters Fact Check | ) www.reuters.com time to read: +6 min

Polymerase chain reaction (PCR) test kits for COVID-19 use what’s known as gene cloning – not reproductive cloning – to detect the presence or absence of the SARS-CoV-2 virus, but social media posts claim that humans are being cloned using COVID-19 PCR tests. The claim appears to originate from an Aug. 18 segment of the Stew Peters Show titled, “Patent PCR Test Linked To Human Cloning Video Shows Animal Experiments, Cross Species Genetics” (here). The 2015 paper by Hoseini and Sauer explains methods for gene cloning with PCR and used a gene encoding a red fluorescent protein as its example. PCR tests for COVID-19 cannot be used for human cloning. Molecular cloning, or gene cloning, that is described in a 2015 paper about using PCR to copy individual genes is an entirely different process.

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