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CNN —Obesity isn’t just a matter of food and exercise — it may be in your genetic code, according to new research. In this study, however, we found a clear genetic trigger for obesity,” said lead study author Dr. Mattia Frontini, British Heart Foundation senior fellow and an associate professor in cellular biology at the University of Exeter in the United Kingdom, in an email. Researchers used data from the UK Biobank, a large biomedical database and research resource that follows people long term, according to the study published Thursday in the journal Med. Women with the gene mutation weighed an extra 4.6 kilograms (10.14 pounds), and men with the variant weighed an extra 2.4 kilograms (5.29 pounds), according to the study. Research into genetic factors and potential treatments is still underway, but Scherer said the current best approach to medical treatment of obesity is GLP-1 medications.
Persons: , Mattia Frontini, Frontini, isn’t, Philipp Scherer, ” Scherer, , ” Frontini, Scherer, Brooke Alpert, Emily Feig Organizations: CNN, Heart Foundation, University of Exeter, Touchstone Diabetes, University of Texas Southwestern Medical Center, National Institute of Diabetes, Research, Massachusetts General Hospital Locations: United Kingdom
With that market shaking out this year, one obesity care startup just scooped up another. Knownwell, which provides obesity-centered primary care and weight management, has acquired Y Combinator startup Alfie Health, Business Insider has learned exclusively. But many investors leaned away from backing obesity care startups as the virtual prescription-focused model clashed with medication shortages. AdvertisementKnownwell has taken a different approach to weight management, with in-person providers alongside its virtual care services, and primary care in addition to obesity care. Alfie HealthGetting obesity care rightBoyarsky Pratt founded Knownwell alongside Dr. Angela Fitch, the president of the Obesity Medicine Association and the former associate director of Massachusetts General Hospital's weight care center.
Persons: , Alfie, Alexander Singh, Ozempic, Knownwell, It's, Andreessen Horowitz, Alfie Health, Y Combinator, Nina Capital, Brooke Boyarsky Pratt, Boyarsky Pratt, it's, Angela Fitch, Vineeta, Kindbody, Agarwala Organizations: Service, Health, Business, Alfie Health, Knownwell, Flare Capital Partners, Nina, Obesity Medicine Association, Massachusetts, Oak, Carbon Health Locations: WeightWatchers, Plenty, Needham , Massachusetts, Boston, Massachusetts, Rhode Island, New Hampshire, Dallas, Minneapolis
download the appSign up to get the inside scoop on today’s biggest stories in markets, tech, and business — delivered daily. A year later, in 1975, I had a second manic episode, which landed me in Langley Porter Hospital. I first met Henry when I was a patient myselfI played ping-pong with Henry, a stocky, lively patient around my age. Then I saw his name on my list of patients on the large whiteboard that paired patients with their primary therapists. Advertisement​​Excerpted from The Bipolar Therapist: A Journey from Madness to Love and Meaning by Marcia Naomi Berger.
Persons: , Henry, Langley Porter's, I've, Marcia, Doreen, I'd, Langley Porter, Henry —, Barbara, Marcia Naomi Berger Organizations: Service, Langley Porter Hospital, Business, Elmhurst, Bitachon Press Locations: Queens , New York, San Francisco, Langley Porter, earshot
The Woman Who Could Smell Parkinson’s
  + stars: | 2024-06-14 | by ( Scott Sayare | ) www.nytimes.com   time to read: +1 min
Joy’s had always been an unusually sensitive nose, the inheritance, she believes, of her maternal line. Les only learned of Joy’s peculiar nose well after their relationship began, on a trip to the Scandinavian far north. Joy would not stop going on about the creamy odor of the tundra, or what she insisted was the aroma of the cold itself. Faced with the prospect of tending to his mother alone, however, Les begged her to stay in Scotland. He trained as a doctor, she as a nurse; they married during his residency.
Persons: Joy’s, Joy, quizzing, Les, anesthesiologist Organizations: General Hospital Locations: Paris, Rome, Scotland, Macclesfield, Manchester, England
Their study found that a 10% increase in processed food consumption was linked to a higher risk of cognitive impairment. That means you can't offset the consequences of a junk food diet by popping some multivitamins or gulping a green juice afterward. We're feeding a really complicated ecosystem in the gut that helps metabolize what we eat," Kimberly said. Aim for ingredients you recognizeYou don't have to give up processed foods completely to improve your health. In the long run, it can be more helpful to make a few small swaps you can stick to than trying (and failing) to swear off processed foods forever.
Persons: , W, Taylor Kimberly, he's, Kimberly, I've, hasn't, they're Organizations: Service, Harvard Medical School, Massachusetts General Hospital, Business Locations: Massachusetts
Over the last three years, a new class of Alzheimer’s drug, the first to treat a root cause of the disease, has set off a roller coaster of hope and disappointment. Lecanemab (brand name Leqembi; pronounced le-KEM-bee) was given full approval by the Food and Drug Administration in July 2023 and is currently the only one of its class available to Alzheimer’s patients, outside clinical trials. The drug has been shown to slow the progression of the disease, but its benefits are fairly modest. With lecanemab having been approved for nearly a year — and with a similar drug, donanemab, being reviewed by an F.D.A. There are strict requirements for patients to be eligible for lecanemab; by one estimate, fewer than 20 percent met the qualifications for the medication.
Persons: Neurologists Organizations: Food and Drug Administration, New York Times, Mayo Clinic, Mayo Clinic , Massachusetts General Hospital, University of California Locations: Mayo Clinic , Massachusetts, San Francisco
The Toussaint Louverture International Airport, which has reopened after being closed for nearly three months due to gang violence, in Port-au-Prince, Haiti, on May 20. Montis and the Lloyds barricaded themselves inside their residence on the compound, but it was not enough, Lloyd told CNN. US Ambassador to Haiti Dennis Hankins walks after Haiti’s transitional council ceremony, on the outskirts of Port-au-Prince, Haiti on April 25, 2024. The situation on the ground in Port-au-Prince remains anarchic,” he warned. But Thursday morning, the bodies of Davy and Natalie Lloyd finally began their long journey home.
Persons: Davy, Natalie Lloyd, Haiti Dennis Hankins, , Toussaint, Ralph Tedy Erol, Jude Montis –, Davy Lloyd’s, David Lloyd, Lloyd, Eric Burlison, Sen, Josh Hawley, ” Burlison, we’ve, ” Natalie Lloyd’s, Naomi Baker, Ben Baker, Stacy Librandi Bourne, Vitel’homme, , Baryé, ” Innocent, Judes Montis, Odelyn Joseph, Gary Desrosiers, Eunide Majeur Montis, Jude Montis, Cassidy Anderson, , Natalie, Champ de Mars, Hawley, Biden, “ Natalie, CNN’s AnneClaire Stapleton, Hande Atay Alam, Natalie Barr, Nikki Carvajal Organizations: CNN, Prince, US, Kansas City, US State Department, Reuters, Local carrier Sunrise, Lloyds, White, Missions, Missouri US, US National Security, State Department, US Embassy, , AP, HERO, Haiti’s National Police, Baker’s, General Hospital, Champ Locations: Haiti, American, Port, Miami, Kansas, United States, Prince, Haiti’s, Caribbean, Eric Burlison , Missouri, Missouri
CNN —Johnny Wactor, an actor who formerly starred in “General Hospital,” caught people in the act of stealing the catalytic converter from his car Saturday. But, up to last year, catalytic converter thefts had been rising sharply, up by a factor of four, since 2020. A catalytic converter cleans a car’s exhaust, making the air safer to breathe for all of us. On its website, the US Environmental Protection Agency has called the catalytic converter “one of the great environmental inventions of all time.” But it’s not what the catalytic converter does that attracts desperate criminals. For the most part, the catalytic converters end up getting sold to recycling companies that strip out the materials to make new catalytic converters.
Persons: Johnny Wactor, , Wactor, It’s, they’ve, Richard Waitas, That’s, Scott Vollero, Christopher Gaines, you’ve, it’s Organizations: CNN, , National Insurance, US Environmental Protection Agency, National Automobile Dealers Association, Recycling Locations: Angeles, California
The use of weed to replace alcohol is a growing trend in the United States. “We know that moderate alcohol consumption has health risks, and risk increases as alcohol consumption increases,” Boyd said in an email. “Cannabis smoke contains toxins, carcinogens, and particulate matter that have been linked to cancer, lung damage, and cardiovascular disease,” Cohen said in an email. Research on edibles, such as baked goods, candies and beverages, and other methods of using cannabis is in its infancy. “In and of itself, it’s not good that more people are using cannabis,” Grinspoon said.
Persons: CNN —, , , , “ I’ve, Carol Boyd, ” Boyd, Weed, Peter Grinspoon, ” “, ” Grinspoon, Beth Cohen, ” Cohen, I’m, Boyd, ” Robert Page II, Grinspoon, ideation, it’s Organizations: CNN, National Survey, Center, Drugs, University of Michigan, US Centers for Disease Control, Massachusetts General Hospital, Marijuana, University of California, University of Colorado Skaggs School of Pharmacy, Pharmaceutical Sciences, Drug, Food and Drug Administration, National Poison Center, FDA, Lifeline Locations: United States, Washington, Ann Arbor, Boston, San Francisco, Aurora, Georgia
Johnny Wactor, who played Brando Corbin on "General Hospital," was shot and killed in LA. "General Hospital" said it was "heartbroken" about Wactor, who left the show in 2022. AdvertisementJohnny Wactor, best known for his role as Brando Corbin on "General Hospital," was shot and killed in Los Angeles, family members of the actor told media outlets. Wactor's brother confirmed to local station KTLA that the 37-year-old actor was shot and killed early Saturday morning in a theft that turned deadly. This story is available exclusively to Business Insider subscribers.
Persons: Johnny Wactor, Brando Corbin, , Wactor's Organizations: General, Service, KTLA, Los Angeles Police Department, Business Locations: LA, Los Angeles
Johnny Wactor, an actor best known for his role in “General Hospital,” was shot and killed on Saturday, reports said, amid what his family described as an attempted theft of a catalytic converter in Los Angeles. The fatal shooting took place around 3 a.m. on Saturday, when Mr. Wactor approached three men in downtown Los Angeles, The Associated Press reported, citing the Los Angeles Police Department. His mother, Scarlett Wactor, told the local news station ABC7 that Mr. Wactor left the rooftop bar where he worked late in the evening and was walking with a co-worker toward his vehicle when he interrupted someone who was in the process of stealing the vehicle’s catalytic converter. Ms. Wactor said her son thought his car was being towed at first, and when he approached the person to ask, the person “looked up, he was wearing a mask, and opened fire.”
Persons: Johnny Wactor, , Wactor, Scarlett Wactor Organizations: , Associated Press, Los Angeles Police Department, ABC7 Locations: Los Angeles
CNN —Former “General Hospital” actor Johnny Wactor was fatally shot in downtown Los Angeles while interrupting thieves Saturday, according to his agent and CNN affiliate KABC. Her son initially thought his car was being towed, and he approached the person to ask, Scarlett Wactor told KABC. The shooting occurred around 3:25 a.m. PT Saturday, Los Angeles Police Department Officer Tony Im told CNN. One of the suspects pulled out a gun and shot the victim before the men drove off in a vehicle. Wactor starred in “General Hospital” as Brandon Corbin from 2020 to 2022, according to IMDB.
Persons: Johnny Wactor, Brando Corbin, David Shaul, , ” Wactor, Shaul, Johnny, , Scarlett Wactor, Tony Im, Wactor, Brandon Corbin Organizations: CNN, , KABC, Los Angeles Police, LAPD Locations: Los Angeles, Siberia
All three diets are plant-based, focused on consuming more fruits and vegetables, whole grains, beans and seeds while limiting sugar, red meat and ultraprocessed foods. Eating more ultraprocessed foods such as hot dogs is linked to a higher risk of stroke and cognitive decline, according to a new study. What is it about ultraprocessed foods that may allow them to sabotage efforts to follow a healthy diet? Growing dangers of ultraprocessed foodsStudies on the dangers of eating ultraprocessed foods are piling up. That 10% increase was considered “baseline,” and adding even more ultraprocessed foods might increase the risk, experts say.
Persons: , Andrew Freeman, ’ ”, Dr, W, Taylor Kimberly, Kimberly, Peipei Gao, Zhendong Mei, Mei, Gao, Harvard T.H, ’ ” Freeman Organizations: CNN, Jewish Health, Whites, Blacks, Massachusetts General Hospital, Brigham, Women’s Hospital, Harvard, of Public Health Locations: Denver, Massachusetts, Boston, Chan
At the time I thought I might want to have kids, and Barry thought he probably didn't. During college I told my mother that I worried that I wouldn't make a good parent because I didn't enjoy children much. Louisa Rogers and her husband Barry enjoy spending time with their grandsons. On the other hand, I married Barry knowing he was uncertain, so my wish couldn't have been that strong. Since I have many peers who, like me, don't have biological children, I don't feel alone.
Persons: , Barry, Louisa Rogers, That's, I'd, I'm Organizations: Service, Business, Honda, San Francisco General Hospital Locations: Washington, DC, Mexico
The hospital staff, like many in Haiti right now, are doing the best they can with what little they have. "We have had no significant medical supplies delivered in weeks." Food has also been tough to come by, although the World Food Programme has been trying to fill in the gaps. But its supplies are dwindling, too, and there have been shortfalls in donor funding for the UN's Humanitarian Response Plan. Clarke was able to return to the capital of Port-au-Prince earlier this month via a World Food Programme helicopter.
Persons: Giles Clarke, Petit, Frere Arabella, Jacob Burns, Médecins, Clarke, , Ariel Henry Organizations: Justinien University, Food Programme, Contractors Locations: Cap, Haïtien, Haiti, Caribbean, Port, Kenya
CNN —A 64-year-old British man is receiving “critical care” after he was attacked by a shark 10 meters from the shore in Scarborough, Trinidad and Tobago. According to Farley Chavez Augustine, the Chief Secretary of Tobago, the man was attacked on Friday morning local time by what appeared to be a bull shark. The people accompanying the man “were trying to physically fight off the shark” after it attacked, Jakerov added. The Tobago House of Assembly offered a $10,000 Trinidad and Tobago Dollar reward (around $1,470 USD) for the successful capture of the shark, but later recalled this bounty. The British High Commissioner to Trinidad and Tobago posted travel guidance related to the attack on X, noting the closure of the marine park.
Persons: Farley Chavez Augustine, Augustine, ” Augustine, Augustine said, Orion, Jakerov Organizations: CNN, Scarborough General Hospital, Trinidad, Tobago Television, Tobago House, Assembly, British Locations: Scarborough, Trinidad and Tobago, Tobago, Caribbean, United Kingdom, State, Trinidad
In a “detailed, undeniable, unconflicted” deathbed confession to one of the investigators in the case earlier this month, Larry Webb admitted to fatally shooting Natasha “Alex” Carter, who was 10 at the time, and her mother, Susan Carter, nearly 24 years ago, Hatfield said. Webb told the investigator some of his cash in the home went missing, and Webb suspected Susan Carter had “spent a lot of money. “Almost lost hope several times.”Webb had been a suspect from the start of the investigation, authorities said. “The confession aligned with exactly the investigative efforts and the evidence collected” by authorities, Hatfield noted. Hours later, the bodies of Susan and Alex Carter were found, Hatfield said.
Persons: Benjamin Hatfield, unconflicted, Larry Webb, Natasha “ Alex ” Carter, Susan Carter, Hatfield, Webb, , ” Hatfield, Alex, Susan, ” Webb, Alex’s, Rick Lafferty, ” “ It’s, ” Lafferty, Carter, Alex Carter, Lafferty, Organizations: CNN, Authorities, Mount, Mount Olive Correctional, Montgomery General Hospital Locations: West Virginia, Raleigh County, Hatfield, Mount Olive, Montgomery
CNN —It’s 420 or “weed day,” and people around the world will be paying homage to their favorite guilty pleasure: marijuana. “I worry when people are in an enclosed space because new data is beginning to show that secondhand marijuana smoke may be just as dangerous as the primary smoke,” Page said. “Approximately 3 in 10 people who use marijuana have marijuana use disorder,” according to the US Centers for Disease Control and Prevention. In fact, some parents told doctors they believed vaping marijuana was safer than tobacco, Boyd told CNN earlier via email. A cloud of marijuana smoke rises as a clock hits 4:20 p.m. during the Mile High 420 Festival in Denver on "weed day" in 2022.
Persons: CNN —, Dr, Beth Cohen, Cohen, , , Robert Page II, ” Page, Weed, It’s, ’ ” Carol Boyd, Ann Arbor, Peter Grinspoon, ” Young, Sam Wang, Boyd, Grinspoon, Patrick T, Fallon, Nixon, ” Boyd, ” Grinspoon, ’ ”, Page Organizations: CNN, District of Columbia, University of California, University of Colorado Skaggs School of Pharmacy, Pharmaceutical Sciences, Center, Drugs, University of Michigan, US Centers for Disease Control, Prevention, CDC, Massachusetts General Hospital, Marijuana, Children’s Hospital, Yale Medicine, Drug, University of Colorado’s, Getty, University of Mississippi, US Drug, Administration Locations: United States, San Francisco, Colorado, Aurora, Ann, Boston, Children’s Hospital Colorado, Denver, AFP
After 'The Jinx' ended, Durst was finally charged with Berman's murder and convicted in 2021Durst in prison. AdvertisementTwo days after his arrest, on March 16, 2015, Durst was officially charged with Berman's murder. Two months later, on September 17, 2021, Durst was finally convicted for Berman's murder and later sentenced to life in prison without the possibility of parole. Weeks later, Durst was also indicted in the 1982 murder of his wife. But that case never made it to trial because Durst died in January 2022.
Persons: , Robert Durst, who'd, Durst, Kathleen McCormack, Susan Berman, he'd, Berman, He'd, Morris Black, Black, Jon Stewart, Seymour Durst, Andrew Jarecki's, McCormack, wasn't, Berman's, didn't, Weeks, Chip Lewis Organizations: Service, HBO, Authorities, Business, New York Times, Los Angeles County, Prosecutors, The New York Times, San Joaquin General Hospital Locations: York, Beverley, Los, Stockton , California
Read previewShannen Doherty, the actor best known for her role in "Beverly Hills, 90210," has stage 4 cancer. She's getting rid of her material possessions so she can focus on spending time with her mother. "I'm getting rid of a lot of clothes, I'm getting rid of a lot of old stuff, the charity shop loves me," Godley said. But one thing they can control is their material possessions," Morin said. "Selling things, sorting through items, and getting rid of stuff they no longer need may help them feel more in control over something."
Persons: , Shannen Doherty, doesn't, " Doherty, Doherty, Michael Douglas, Janey Godley, Lorraine Kelly, Doherty —, Godley, it's, Jeffrey Peppercorn, Amy Morin, Morin, Peppercorn Organizations: Service, Business, Hollywood, Massachusetts General Hospital Cancer, Survivorship Locations: Beverly Hills, Scottish, Massachusetts
In addition to the physical benefits of exercise, it’s also associated with a reduction in stress signals in the brain, which leads to a decreased risk of cardiovascular disease, according to the study. For people without any history of depression, the benefit of exercise on cardiovascular disease reduction plateaued after about 300 minutes of moderate physical activity a week. How it worksExercise reduced stress signals and increased prefrontal cortical signals, Tawakol said. In part, exercise appeared to reduce heart disease risks by reducing the stress signals, Tawakol said. But figure out a way to get a physical activity in that you truly enjoy,” he said.
Persons: it’s, Brigham Biobank, , Ahmed Tawakol, , Andrew Freeman, Freeman, Tawakol, ” Tawakol, wasn't, Oleg Breslavtsev, Karmel Choi, ” Freeman Organizations: CNN’s, CNN, Mass, American College of Cardiology, Mass General Hospital, Harvard Medical School, Jewish Health, Getty, Massachusetts General Hospital Locations: Boston, Denver, Massachusetts
Why is pop culture so obsessed with nuns?
  + stars: | 2024-04-12 | by ( Leah Dolan | ) edition.cnn.com   time to read: +5 min
These vestal get-ups are, in fact, the latest in a long line of subversive pop culture interpretations of the lives (and loves) of nuns. More recently, Bella Hadid walked the Coperni Fall-Winter 2022 runway wearing headgear reminiscent of a nun’s habit. The “Nunsploitation” subgenre saw the transformation of nuns from icons of piety and sacrifice into harbingers of evil and sexual obsession. In lighter fare, “Sister Act 3,” a third movie in the beloved “Sister Act” series of the 1990s starring Whoopi Goldberg is currently in development. “The juxtaposition of the nun’s habit with either blatant sexuality or the cultivation of personal identity and style is shocking and grabs people’s attention,” wrote Dr. Neal.
Persons: Rihanna, Sydney Sweeney, vestal, Dior, John Galliano, Serre, Emilia Wickstead, Bella Hadid, Sydney Sweeney's, Hulton, , Andy Warhol, Ingrid Bergman, , Ken Vrana, Yoshitomo Nara, Lynn S, Neal, Audrey Hepburn, Christ, Lust ”, Saint Valentine ”, Sister Gertrude, Nadia Lee Cohen, Saint Maud ”, , Whoopi Goldberg, Suzanne Hanover, Sweeney — Organizations: CNN, Couture, Deutsch, Pew Research Center, Cannes Film Locations: Maison, Sydney, Italy, Swedish, America
Breakfast provides the brain with its first source of energy every morning. Fueling the brain is key for focus, clarity, and optimal functioning throughout the day. They also contribute to the neuroinflammation (inflammation around the brain) that's associated with brain fog and poor concentration. After that, here are five of my favorite breakfast brain foods. They're rich in key nutrients and functional compounds that promote better energy, clarity, and mental health.
Organizations: Psychiatry, Massachusetts General Hospital Locations: U.S, Massachusetts
CNN —Rick Slayman, the world’s first living recipient of a genetically edited pig kidney transplant, was discharged from the hospital Wednesday, two weeks after his operation, Massachusetts General Hospital said in a statement. “He is recovering well and will continue to recuperate at home with his family,” the hospital said on X, formerly Twitter. Rick Slayman in his hospital room at Massachusetts General Hospital before his discharge on Wednesday April 3, 2024. Michelle Rose/Massachusetts General HospitalHis surgery is the third such xenotransplant of a pig organ into a living human. The first two transplants were hearts transplanted into living patients that had run out of other transplant options.
Persons: Rick Slayman, Slayman, I’ve, , Michelle Rose, Dr, Sanjay Gupta, ” Slayman Organizations: CNN, Massachusetts General Hospital, Massachusetts Department of Transportation, CNN Health, Procurement, Transplantation Network Locations: Massachusetts, U.S
The first patient to receive a kidney transplanted from a genetically modified pig has fared so well that he was discharged from the hospital on Wednesday, just two weeks after the groundbreaking surgery. The transplant and its encouraging outcome represent a remarkable moment in medicine, scientists say, possibly heralding an era of cross-species organ transplantation. Two previous organ transplants from genetically modified pigs failed. In one patient, there were signs that the immune system had rejected the organ, a constant risk. But the kidney transplanted into Richard Slayman, 62, is producing urine, removing waste products from the blood, balancing the body’s fluids and carrying out other key functions, according to his doctors at Massachusetts General Hospital.
Persons: Richard Slayman Organizations: Massachusetts General Hospital Locations: Massachusetts
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