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☆ Drugmakers bet billions that targeted radiation could become the next cancer breakthrough
▼ + stars: | 2024-09-16 | by ( Angelica Peebles | In Angelicapeebles | ) www.cnbc.com time to read: +9 min

watch nowDrugmakers are betting that delivering radiation directly to tumors will become the next big cancer breakthrough. That can allow the treatment to deliver radiation to cancer cells and spare the rest of the body from the level of damage that comes with many cancer drugs. For Pluvicto, patients come in once every six weeks for up to six treatments. One opportunity Bristol Myers Squibb sees is combining radiopharmaceuticals with existing cancer drugs like immunotherapy, said Robert Plenge, Bristol's chief research officer. But she thinks the technology will become an important part of cancer drugs in the next decade.

Persons: Eli Lilly, They've, Michael Schmidt, Schmidt, Franco Origlia, Jacob Van Naarden, Eli Lilly's, Lilly, Biopharma, Van Naarden, Radiopharmaceuticals, Bristol Myers, Ben Hickey, RayzeBio, Hickey, Victor Bulto, Bulto, Timothy Korytko, Ronald Coy, Sharon, Ronald Coy Ronald Coy, Coy, who's, Coy hasn't, she's, we've, Eli Lilly's Van Naarden, Bristol Myers Squibb, Robert Plenge, Susan Galbraith, Galbraith Organizations: Bristol Myers Squibb, AstraZeneca, Guggenheim Securities, Novartis, NSA, Pharmaceutical, Bassett Healthcare Network, Bristol, Fusion Pharmaceuticals, Guggenheim Locations: Aedea Rome, Italy, radiopharmaceuticals, Swiss, FactSet, Bristol, Indiana, U.S, New York, Bassett

☆ Chad McQueen, ‘Karate Kid’ star and son of Steve McQueen, dead at 63
▼ + stars: | 2024-09-13 | by ( Lianne Kolirin | ) edition.cnn.com time to read: +3 min

CNN —Actor Chad McQueen, son of Hollywood legend Steve McQueen, has died at age 63. McQueen starred as Dutch opposite lead actor Ralph Macchio in the "Karate Kid" movies. Actor Steve McQueen relaxes with his daughter Terry and his son Chad as he stars in the movie "Le Mans" in Le Mans, France on June 24, 1971 . Posting on X, Hurwitz described McQueen as a “Karate Kid legend,” adding: “Unfortunately, Chad was unable to join us when it came time to shoot. He kicked ass.”He added: “The fandom mourns a Karate Kid legend today.

Persons: Chad McQueen, Steve McQueen, McQueen, Ralph Macchio’s, Arthur H, Barens, Jeanie Galbraith, Chase, Madison, Ralph Macchio, ” McQueen, Steven R, McQueen –, “, ” Chad McQueen, Steve McQueen ”, Terry, Chad, Henri, ”, McQueen’s, you’re, Jon Hurwitz, “ Cobra Kai, Hurwitz Organizations: CNN, Dutch, Associated Press, Columbia Pictures, AP, Le, Netflix Locations: Le Mans, France, Mexico, Madison

☆ AI stock frenzy resembles dot-com bubble and may explode disastrously, experts warn
▼ + stars: | 2024-06-20 | by ( Theron Mohamed | ) www.businessinsider.com time to read: +4 min

Experts say the AI mania has shades of the dot-com and housing bubbles and could end painfully. AdvertisementExperts say the frenzy around AI stocks resembles the last two major market bubbles — and could end in disaster if investors get spooked. "This is the goofiest and likely most dangerous concentration of overvaluation I've seen in 34 years investing and throughout financial history," Bloomstran said. Some experts have compared Nvidia to Cisco, the network hardware company whose stock ballooned during the dot-com bubble before ultimately crashing. No one can predict if the AI craze will end with a devastating crash like the dot-com and housing bubbles, or usher in a new market regime led by Nvidia and its kin.

Persons: —, Nathan Burks, Adetokunbo Fadahunsi, Ann Marie Hibbert, Burks, Hibbert, Chris Bloomstran, Semper Augustus, I've, Bloomstran, John Chambers, Robert Galbraith, it's Organizations: Service, George Mason University, Big Tech, Nvidia, Microsoft, Cisco, REUTERS, Wall Street Journal Locations: West Virginia

☆ Tiger Woods’ 15-year-old son Charlie to attempt US Open qualification
▼ + stars: | 2024-04-25 | by ( Jack Bantock | ) edition.cnn.com time to read: +3 min

On Thursday, Charlie Woods will look to pen a chapter of his own. Tiger Woods’ 15-year-old son will tee up at an 18-hole local qualifier in Port St. Lucie, Florida, as one of an 84-player field vying for a spot at the 124th edition of the major. Ben Jared/PGA TOUR/Getty ImagesWoods is one of 10,052 entries for US Open qualifying this year with hopefuls – who must have a handicap not exceeding 0.4 or be professional to be eligible – spanning all 50 states and 70 foreign countries. Woods celebrates his third US Open victory in 2008. Woods is not yet among the field, but could still receive a special exemption to play from the USGA.

Persons: Charlie Woods, Woods, –, ‘, Wyndham Clark, Ben Jared, Beck Patrick, Keith Crimp, Woods ’, Robert Galbraith, Scottie Scheffler Organizations: CNN, Tennis Club, Pinehurst, Country Club, PNC, PGA, Lake Golf, US, USGA, Los Angeles Country Club, Reuters, Augusta National Locations: Port St, Lucie , Florida, North Carolina, Hobe Sound, Florida, Pinehurst, Houston , Texas, Washington

☆ AstraZeneca: Fusion acquisition will be a cost effective-investment that can improve cancer outcomes
▼ + stars: | 2024-03-19 | by ( ) www.cnbc.com time to read: 1 min

Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailAstraZeneca: Fusion acquisition will be a cost effective-investment that can improve cancer outcomesDr. Susan Galbraith, executive vice-president of oncology and R&D at AstraZeneca, discusses the healthcare giant's $2.4bn acquisition of Fusion Pharmaceuticals.

Persons: Susan Galbraith Organizations: AstraZeneca, Fusion, Fusion Pharmaceuticals

☆ AstraZeneca bets on new cancer treatments with $2 billion Fusion Pharma purchase
▼ + stars: | 2024-03-19 | by ( ) www.cnbc.com time to read: +2 min

AstraZeneca said on Tuesday it will buy clinical-stage biopharmaceutical company Fusion Pharmaceuticals Inc for about $2 billion in cash as the Anglo-Swedish drugmaker bets on next-generation cancer treatments. The drugmaker will pay $21 per Fusion share, a premium of more than 97% to the U.S.-listed company's closing price on Monday. Fusion is developing "next-generation" radioconjugates (RCs) to treat cancer. RCs deliver a radioactive isotope directly to cancer cells through precise targeting using molecules and have emerged as a promising modality in cancer treatment over recent years, AstraZeneca said. Radiotherapy and chemotherapy have been the mainstays of cancer treatment for decades.

Persons: AstraZeneca, Susan Galbraith Organizations: Fusion Pharmaceuticals Inc, Amolyt Pharma, AstraZeneca, Fusion, Oncology, U.S . Food, Drug Administration, FDA Locations: Swedish, U.S, radioconjugates

☆ 10 fascinating facts about Nvidia CEO Jensen Huang, who has a company tattoo and dozens of direct reports
▼ + stars: | 2024-02-27 | by ( Aaron Mok | ) www.businessinsider.com time to read: +6 min

Nvidia cofounder and CEO Jensen Huang is on track to be one of the richest people in the world. Here are 10 surprising facts about Huang, from his Nvidia tattoo to his staggering number of direct reports. AdvertisementJensen Huang, the CEO and cofounder of Nvidia, is leading the charge towards an AI future — with his company making billions. He has a tattoo of Nvidia's logo on his shoulderNvidia founder, president and CEO Jensen Huang displays his tattoo in September 2010. "The more direct reports the CEO has, the less layers are in the company," Huang said during an interview at the 2023 DealBook Summit.

Persons: Jensen Huang, Huang, —, who's, it's, Lori, Chris Malochowsky, Curtis Priem, Robert Galbraith, you've, Fortune, Noah Berger, what's, He's, he'll, Jackie Chan Organizations: Nvidia, Service, Oneida Baptist Institute in, Wired, NPR, Oregon State University, HP, Stanford, New York Times, Wilson Jackets, New Yorker, Yorker, New York Times DealBook Locations: Oneida Baptist Institute in Kentucky, California, Shutterstock

☆ What it’s really like to go to the Super Bowl
▼ + stars: | 2024-02-10 | by ( Harmeet Kaur | Scottie Andrew | ) edition.cnn.com time to read: +14 min

The person who attended the Super Bowl nine timesMike Quackenbush has been to the Super Bowl nine times — but he didn’t personally pay for tickets because, technically, he was there on business. It’s a great event and I was super lucky to go all those years.”The first-time Super Bowl attendee who went during the pandemicChelsea Bear was all smiles at the 2021 Super Bowl. Lennox McLendon/AP Most rushing yards in a Super Bowl: Washington quarterback Doug Williams won the Super Bowl MVP award in 1988, but rookie running back Timmy Smith set a Super Bowl record that year with 204 rushing yards against Denver. Ezra Shaw/Getty Images Longest pass in a Super Bowl: Carolina wide receiver Muhsin Muhammad caught an 85-yard touchdown pass from Jake Delhomme during Super Bowl XXXVIII in 2004. Paul Sancya/AP First score in Super Bowl history: In the first quarter of what we know now as Super Bowl I, Green Bay Packers wide receiver Max McGee scored a touchdown on a 37-yard pass from Bart Starr.

Persons: who’ve, who’d, —, he’d, Mike Quackenbush, didn’t, Quackenbush, Washington Redskins —, ”, he’ll, Peyton Manning’s, it’s, It’s, Bear, Chelsea Bear, Chelsea Bear’s, Chloe, ” Bear, couldn’t, Tom Brady —, I’ll, San, Judy Abad, “, Steve Young, Tom DiPace, Tom Brady, Brady, John David Mercer, Jerry Rice, Lennox McLendon, Doug Williams, Timmy Smith, Bob Galbraith, Rod Martin, Jeff Roberson, Bill Belichick, Belichick, Al Bello, Baltimore's Jacoby Jones, Ezra Shaw, Muhsin Muhammad, Jake Delhomme, Brian Bahr, Willie Parker, Paul Spinelli, Pittsburgh's James Harrison, Kurt Warner, Leon Lett, Lett, Buffalo's Don Beebe, Rick Stewart, Manny Ramirez, Peyton Manning, Denver's Knowshon Moreno, Paul Sancya, Max McGee, Bart Starr, McGee, Neil Leifer, Scott Norwood, Phil Sandlin, Abad, ” Abad, Mike Ryan, Chris Jeter, Ryan, Patrick Mahomes wasn’t, “ I’d Organizations: CNN, Super, Kansas City Chiefs, San Francisco 49ers, NFL, Super Bowl, NFL Players Association, Bowls, Washington Redskins, Buffalo Bills, Chelsea, Chiefs, Tampa Bay Buccaneers, South Florida, Bucs, New England Patriots, Philadelphia, Patriots, Atlanta, USA, Cincinnati, Famer, Washington, Denver, Oakland, Raiders, Philadelphia Eagles, New, New York Giants, Ravens, San Francisco, Getty, Pittsburgh, Dallas Cowboys, Rose, Green Bay Packers, San, 49ers, Buffalo, Bills, Kansas City, Bowl, I’m Locations: Tampa, San Francisco, Diego, Francisco, New England, Carolina, Denver, Seattle, Kansas, Miami

☆ What Wall Street bosses from Goldman Sachs to JPMorgan are saying about the jobs outlook for 2024 in investment banking, wealth management, and more
▼ + stars: | 2024-01-16 | by ( Emmalyse Brownstein | Alex Morrell | Reed Alexander | ) www.businessinsider.com time to read: +11 min

Last year, banks opened 2023 by forecasting layoffs, including for the investment bankers who suddenly had nothing to do following the pandemic-era M&A and IPO boom. Citigroup kicked off 2024 ominously, warning that it will lay off as many as 20,000 employees by 2026. The bank expects 2024 expenses to increase further to total $90 billion, up $2.8 billion from 2023, and much of that will be focused on hiring. CFO Barnum on Friday said the bank is gearing up for a "rebound in the investment banking wallet." Headcount declined 3% to 80,006 from 82,427, while compensation expenses rose to $24.5 billion from $23 billion.

Persons: It's, it's, Jane Fraser, Jeremy Barnum, JPMorgan Chase Jamie Dimon, JPMorgan Chase, Alex Wroblewski, JPMorgan's headcount, Barnum, Friday, Patrick T, Fallon, —, Fraser, Q, Goldman Sachs Goldman Sachs, David Solomon, BRENDAN MCDERMID, Goldman Sachs, Denis Coleman, Coleman, Goldman, Bank of America Brian Moynihan, Robert Galbraith, headcount, BofA, Alastair Borthwick, execs, they've, Brian Moynihan, Wells Fargo Charles Scharf, Lucy Nicholson Wells Fargo, Michael Santomassimo, Charlie Scharf, Santomassimo, BlackRock Larry Fink, Fink, Kapito, Morgan Stanley Ted Pick, Morgan Stanley, Jeenah, Headcount, Morgan, Ted Pick, Sharon Yeshaya, Blackstone Steven Schwarzman, Blackstone, Gonzalo Fuentes Organizations: Business, Citigroup, JPMorgan, Citi, BlackRock, Blackstone, Getty, AlphaSense, Citigroup Citigroup, Bank of America, REUTERS, Robert, Robert Galbraith Bank of America's, Reuters, AP BlackRock, Global Infrastructure Partners Locations: Wall, headcount, Wells Fargo

A Salesforce sign is seen during the company's annual Dreamforce event, in San Francisco, California November 18, 2013. REUTERS/Robert Galbraith/File Photo Acquire Licensing RightsNEW YORK, Nov 30 (Reuters) - Salesforce Inc's (CRM.N) stock jumped by about 10% on Thursday to a nearly two-year high after the U.S. cloud and business software company reported stellar third quarter results underpinned by strong demand for its services. Salesforce's revenue of $8.72 billion and adjusted profit of $2.11 per share beat Wall Street expectations, the company reported after the closing bell on Wednesday. Reuters GraphicsMultiple analysts, including from Morgan Stanley, Evercore, Wells Fargo, and Deutsche Bank, raised their price target for Salesforce's shares following the results. Reporting by Chibuike Oguh in New York; Editing by Lance Tupper and Nick ZieminskiOur Standards: The Thomson Reuters Trust Principles.

Persons: Robert Galbraith, Morgan Stanley, Brad Sills, Chibuike Oguh, Lance Tupper, Nick Zieminski Organizations: REUTERS, Reuters Graphics, Deutsche Bank, Global Research, Thomson Locations: San Francisco , California, U.S, Evercore, Wells Fargo, Salesforce, New York

☆ Here are 3 underappreciated aspects of Nvidia's latest knockout quarter
▼ + stars: | 2023-11-22 | by ( Kevin Stankiewicz | In Kevinstankiewicz | ) www.cnbc.com time to read: +6 min

At the same, there are three key areas aspects to Nvidia's business that are increasingly coming into focus that show the company's monstrous growth thus far still has more room to run. NVDA 1Y mountain Nvidia's stock performance over the past 12 months. Networking sales The strength in Nvidia's networking business on display in Tuesday's print underscored the company's evolution into a one-stop shop for AI computing in the data center. But its networking business — which sells communications technology to connect different parts of the data center — has become a larger piece of the puzzle. In fact, Nvidia's networking segment has now surpassed a $10 billion annualized revenue rate, the company said Tuesday.

Persons: Cowen, Bernstein, Cloud, That's, Jensen Huang, Jim Cramer's, Jim Cramer, Jim, Jen, Hsun Huang, Robert Galbraith Organizations: Nvidia, Mellanox Technologies, BMO, Enterprise, Services, Microsoft, Google, Oracle, CNBC Locations: U.S

REUTERS/Andrew Galbraith/File Photo Acquire Licensing RightsSHANGHAI, Nov 3 (Reuters) - The European Union Chamber of Commerce on Friday criticised an upcoming trade fair in China as being more of a "political showcase" than about doing business and pushed for more tangible measures to restore confidence among European companies. "It's more a government affairs event, more a marketing event and there's been really little said on business. You can say CIIE has become more of a political showcase rather than a business event," Carlo D'Andrea, the chamber's vice president, told reporters at a briefing in Shanghai. "European businesses are becoming disillusioned as symbolic gestures take the place of tangible results needed to restore business confidence," he said. The European Union's top diplomat, Josep Borrell, visited last month, as have several other top EU officials in recent months.

Persons: Xi Jinping, Andrew Galbraith, Li Qiang, Anthony Albanese, there's, Carlo D'Andrea, Josep Borrell, Brenda Goh, Sonali Paul Organizations: China, REUTERS, Rights, European Union Chamber of Commerce, Australian, European Union, Micron, Nestle, Burberry, Thomson Locations: Shanghai, China, Europe, EU

☆ Amgen sales rise, but shares off as investors await obesity data
▼ + stars: | 2023-10-31 | by ( Deena Beasley | ) www.reuters.com time to read: +3 min

Third quarter sales of Horizon's gout drug Krystexxa rose to $253 million from $192 million. Amgen raised its post-acquisition forecast for full-year sales to between $28 billion and $28.4 billion from a previous estimate of $26.6 billion to $27.4 billion. Total revenue for the quarter rose 4% to $6.9 billion, in line with analyst expectations. Sales of cancer drug Lumakras fell 31% to $52 million and sales of psoriasis drug Otezla fell 10% to $567 million. Sales of Amjevita, Amgen's new biosimilar version of AbbVie's (ABBV.N) blockbuster arthritis drug Humira, rose 30% to $152 million.

Persons: Robert Galbraith, Amgen, Jefferies, Michael Yee, Bill Smead, Tepezza, We're, we've, Peter Griffith, AMG340, William Blair, Matt Phipps, Lumakras, Otezla, Deena Beasley, Leroy Leo, Bill Berkrot Organizations: REUTERS, Horizon Therapeutics, Smead Capital Management, Wall Street, U.S . Federal Trade Commission, Thomson Locations: South San Francisco , California, California, Los Angeles, Bengaluru

☆ Tiger Woods: How the battle for golf’s soul gave the US golfer new-found purpose – and human connection
▼ + stars: | 2023-10-25 | by ( Don Riddell | ) edition.cnn.com time to read: +22 min

CBS Archive/Getty Images Woods, 6, sizes up a putt in Los Alamitos, California, in 1982. Getty Images/Getty Images Woods hits a tee shot during the 1995 Walker Cup, an international team event. Alexander Hassenstein/Bongarts/Getty Images Woods plays a shot from the ninth fairway during the 2000 US Open in Pebble Beach, California. David Cannon/Getty Images Woods falls to the ground in pain after hitting a shot at The Barclays in August 2013. Jamie Squire/Getty Images Woods and his son, Charlie, warm up before the final round of the PNC Championship in December 2020.

Persons: Woods, Alan Shipnuck, LIV, ” Shipnuck, ” Bryson DeChambeau, Paul Casey, Crushers, Charles Howell III, Anirban Lahiri, Chris Trotman, “ Tiger’s, “ He’s, he’s, “, “ LIV, Greg Norman, Quentin Tarantino, Brooks Koepka, Koepka, David J, Phillip, Mike Douglas, Bob Hope, Jack D, Miller, AP Woods, Rick Dole, Bob Galbraith, David Cannon, Robert Beck, Patrick Murphy, Nike — Woods, Lennox McLendon, Stephen Munday, Earl, Dave Martin, Alexander Hassenstein, Jonathan Ferrey, He's, Andy Lyons, Allsport, Bob May, Fred Vuich, Jack Nicklaus, Nicklaus, Logan Mock, Bunting, Phil Mickelson, Mickelson, Matthew Stockman, Steve Williams, Harry, Williams, Sam, Damian Dovarganes, Rocco, Gary A, Vasquez, Barack Obama, Pete Souza, Stuart Franklin, Elin, Charlie, Ezra Shaw, Eric Gay, Jimmy Fallon, Lloyd Bishop, Arnold Palmer, Chris Condon, Jason Dufner, Lindsey Vonn, Marco Trovati, Lannis, John Amis, Donald Trump, Getty Images Woods, Warren Little, Jamie Squire, Ben Jared, Wally Skalij, Shutterstock Woods, Tiger, Sam Greenwood, Cliff Hawkins, Jonathan Ernst, they’re, Shipnuck, ‘ I’m, Justin Thomas, I’m, ”, they’ve, what’s, Rory McIlroy, Rory, “ Rory, Bryson DeChambeau, ’, he’d, DeChambeau, “ Patrick Reed, Sergio García, “ Phil Mickelson, HyFlyers, Suhaimi Abdullah, Jay Monahan, Yasir Al, Rumayyan, Phil Mickelson’s, Jamal Khashoggi, Prince Mohammed bin Salman, Prince, Mohammad Bin Salman, Reed, Garcia Organizations: CNN, CNN Sport, PGA Tour, LIV, Miami, PGA, Saudi, Public Investment Fund, CBS, AP, Tiger, US Junior Amateur, Getty, Los Angeles, Tour, Stanford University, NCAA, Nike —, Las Vegas, Green, Army, Tiger Woods Foundation, Ford, British, Woods Learning, USA, Office, Stanford, NBCU, Bank, Bay, Invitational, Barclays, Trump, Getty Images, PNC, Law, Los Angeles Times, PNC Championship, Hall of Fame, Reuters, HyFlyers GC, Sentosa Golf, European, MBS, Fox News, ” CNN Locations: Los Angeles, Saudi, Delaware, Tiger’s, Los Alamitos , California, Vietnamese, Vietnam, Orange, United States, France, Hamburg, Germany, Pebble Beach , California, St . Andrews, Scotland, Louisville , Kentucky, Fort Bragg , North Carolina, Hoylake, England, Anaheim , California, Woods, Dublin , Ohio, Beaver Creek , Colorado, Atlanta, Rancho Palos Verdes , California, Pacific Palisades , California, Singapore, London, McIroy

☆ Insurance companies are betting on AI and mass data analytics in a battle against fraud that costs billions
▼ + stars: | 2023-10-24 | by ( Amanda Paule | ) www.businessinsider.com time to read: +9 min

AdvertisementAdvertisementLosses from insurance fraud are nearly double what they were 30 years ago. Scott Clayton, the head of claims fraud at Zurich Insurance Group. AdvertisementAdvertisementOn the other hand, around 40% of fraud is premeditated, and these cases can cost insurance companies upwards of €3,000, or around $3,170, according to the study. But the Insurance Fraud Detection Market is expected to grow from $5 billion in 2023 to $17 billion in 2028. AdvertisementAdvertisementIn the past 10 years, various third-party developers like Friss, IBM, and Shift Technology have started tailoring machine-learning systems to insurance companies.

Persons: —, they're, Alan Turing, It's, Scott Clayton, shallowfakes —, Clayton, I'm, we'll, Arnaud Grapinet, he's, Grapinet, it's, Rob Galbraith, Jennifer Lindberg, Rob Morton, Galbraith Organizations: Service, Coalition Against Insurance, Zurich Insurance, AXA Research Fund, Technology, IBM, Employees Locations: United States, Spain

☆ US agency fines Zipcar for uncompleted recall rentals
▼ + stars: | 2023-10-16 | by ( David Shepardson | ) www.reuters.com time to read: +2 min

A 2015 law requires rental car companies with 35 or more vehicles to complete recall repairs before renting vehicles. The agency is requiring Zipcar, a unit of Avis Budget Group (CAR.O) since 2013, to submit an audit report of all Zipcar vehicles with uncompleted recall repairs at any time within 150 calendar days after the effective date of the settlement. On Monday, Zipcar said the settlement stems from a 2017 recall in which less than 50 of 12,000 vehicles of its global fleet were found in violation. Zipcar added the recall "was a unique mileage-based recall that did not require the immediate grounding of the vehicles" and added the vehicles are no longer in its fleet. "Vehicles with open, unrepaired recalls pose a safety risk to everyone on the road," said Ann Carlson, NHTSA's acting administrator.

Persons: Robert Galbraith, Zipcar, unrepaired, Ann Carlson, NHTSA's, Hertz, David Shepardson, Chris Reese, Paul Simao, David Gregorio Our Organizations: REUTERS, Rights, National, Traffic Safety Administration, Avis Budget Group, Vehicles, NHTSA, Hertz, Thomson Locations: San Francisco , California

☆ Amgen completes $27.8 bln Horizon Therapeutics deal
▼ + stars: | 2023-10-06 | by ( ) www.reuters.com time to read: +1 min

An Amgen sign is seen at the company's office in South San Francisco, California in this October 21, 2013 photo. Amgen, which has gained Horizon's two key products Tepezza and Krystexxa, said it will provide an updated annual forecast during its third-quarter earnings call. RBC Capital Markets analyst Gregory Renza expects Amgen's updated forecast to weave in revenue from Horizon's drugs, which could partially offset the company's "maturing product line". Tepezza could be a "core driver" for Amgen, Renza said, adding that the drug can bring in $3.9 billion in peak sales. Reporting by Mariam Sunny and Sriparna Roy in Bengaluru; Editing by Anil D'Silva and Sherry Jacob-PhillipsOur Standards: The Thomson Reuters Trust Principles.

Persons: Robert Galbraith, Gregory Renza, Renza, Mariam Sunny, Sriparna Roy, Anil D'Silva, Sherry Jacob, Phillips Organizations: Horizon Therapeutics, U.S . Federal Trade Commission, FTC, RBC Capital Markets, Thomson Locations: South San Francisco , California, Bengaluru

☆ Amgen completes $27.8 billion Horizon deal
▼ + stars: | 2023-10-06 | by ( ) www.reuters.com time to read: +1 min

An Amgen sign is seen at the company's office in South San Francisco, California in this October 21, 2013 photo. REUTERS/Robert Galbraith/File Photo Acquire Licensing RightsOct 6 (Reuters) - Amgen (AMGN.O) said on Friday it had completed the $27.8 billion acquisition of Horizon Therapeutics (HZNP.O) after it received the go-ahead from the U.S. Federal Trade Commission (FTC) last month on certain conditions. Under the settlement terms with the FTC following its lawsuit to block the deal, Amgen is prevented from using anticompetitive tactics to extend the market dominance of Horizon's thyroid eye disease treatment Tepezza and gout drug Krystexxa. The deal closure was within the fourth-quarter timeline set by the two companies. Reporting by Mariam Sunny in Bengaluru; Editing by Anil D'SilvaOur Standards: The Thomson Reuters Trust Principles.

Persons: Robert Galbraith, Mariam Sunny, Anil D'Silva Organizations: Horizon Therapeutics, U.S . Federal Trade Commission, FTC, Thomson Locations: South San Francisco , California, Bengaluru

☆ EU starts early-stage probe into Nvidia-dominated AI chip market's abuses - Bloomberg News
▼ + stars: | 2023-09-29 | by ( ) www.reuters.com time to read: +1 min

The logo of technology company Nvidia is seen at its headquarters in Santa Clara, California February 11, 2015. REUTERS/Robert Galbraith/File Photo Acquire Licensing Rights企業 NVIDIA Corp フォローSept 29 (Reuters) - The European Union is examining alleged anticompetitive abuses in chips used for artificial intelligence, a market which Nvidia (NVDA.O) dominates, Bloomberg News reported on Friday, citing people familiar with the matter. Nvidia declined to comment, while the European Commission did not immediately respond to Reuters' request for a comment. France's competition authority raided Nvidia's local offices this week on suspicion the chipmaker engaged in anticompetitive practices, the Wall Street Journal reported on Thursday. Reporting by Chavi Mehta in Bengaluru; Editing by Shilpi Majumdar私たちの行動規範：トムソン・ロイター「信頼の原則」

Persons: Robert Galbraith, Chavi Mehta, Shilpi Majumdar 私 Organizations: Nvidia, REUTERS, NVIDIA, European, Bloomberg, European Commission, Commission, Reuters, Wall Street Locations: Santa Clara , California, Bengaluru

☆ AstraZeneca succession sickness demands urgent fix
▼ + stars: | 2023-09-15 | by ( Aimee Donnellan | ) www.reuters.com time to read: +3 min

LONDON, Sept 15 (Reuters Breakingviews) - Can a CEO be worth $9 billion? That’s the question posed by the 4% fall in AstraZeneca’s (AZN.L) shares following an article stating boss Pascal Soriot may soon resign. The company has played down the report, and its stock has recovered, but the episode highlights its uncertain position were 64-year-old Soriot to leave. Without a clear succession plan, investors should prepare for further swings. Small wonder investors and analysts wonder whether AstraZeneca will be able to find a successor capable of replicating his success.

Persons: Pascal Soriot, AstraZeneca’s, Ivan Menezes, Debra Crew, Soriot, Susan Galbraith, David Fredrickson, Luke Miels, Soriot’s, Neil Unmack, Streisand Neto Organizations: Reuters, Pfizer, pharma, Novartis, Sanofi, GSK, AstraZeneca, Diageo, Thomson Locations: AstraZeneca’s, Swedish

☆ Direxion rolls out Nvidia-focused ETFs for bulls and bears
▼ + stars: | 2023-09-13 | by ( ) www.reuters.com time to read: +2 min

The Direxion Daily NVDA Bull 1.5x Shares ETF (NVDU.O) seeks to deliver 1.5 times the price return of daily moves in Nvidia’s shares, which have more than tripled year-to-date. Meanwhile, the Direxion Daily NVDD Bear 1x Shares ETF allows bearish investors to profit when Nvidia’s shares decline. Single-stock ETFs made their debut in 2022, but only a handful of products have since been introduced by five firms, including Direxion. Because of their increased exposure, investors’ losses in leveraged exchange traded products can be staggering, analysts said. Only four leveraged single-stock ETFs currently have more than $50 million, according to Morningstar.

Persons: Robert Galbraith, “, ”, Bryan Armour, GraniteShares, Direxion, Edward Egilinsky, ” Direxion, Suzanne McGee, Ira Iosebashvili, David Gregorio Our Organizations: Nvidia, REUTERS, Nvidia Corp, Morningstar Inc, Morningstar, Thomson Locations: Santa Clara , California, Nvidia’s

☆ Analysis: FTC settlement could shelter Amgen from US price cuts, taxes
▼ + stars: | 2023-09-05 | by ( Deena Beasley | ) www.reuters.com time to read: +5 min

An Amgen sign is seen at the company's office in South San Francisco, California October 21, 2013. With Horizon, Amgen acquires drugs that won't be affected by new U.S. negotiation requirements for blockbuster medications as well as possible tax advantages stemming from Horizon's headquarters in Ireland. Analysts said the Horizon deal could also help Amgen's tax situation. The United States has largely eliminated once-lucrative corporate tax benefits for pharmaceutical manufacturing operations in Puerto Rico, a U.S. territory. Horizon offers Amgen "potentially a better tax jurisdiction related to Irish manufacturing plants ... Amgen has a new manufacturing process they could potentially move there," Cowen's Werber said.

Persons: Robert Galbraith, Abiel Garcia, John Kness, Donald Trump, Garcia, Evan Seigerman, Lina Khan, Cowen, Biden, Michael Yee, Amgen, Cowen's Werber, Deena Beasley, Peter Henderson, Paul Simao Organizations: REUTERS, U.S . Federal Trade, Horizon Therapeutics, U.S, District, Federal, Activision, Horizon, Amgen, BMO Capital Markets, FTC, Reuters, U.S . Food, Drug Administration, Jefferies, Medicare, Internal Revenue Service, United, Thomson Locations: South San Francisco , California, Amgen, Kesselman, Ireland, U.S, Puerto Rico, United States, Irish

An Amgen sign is seen at the company's office in South San Francisco, California in this October 21, 2013. Under the FTC settlement, Amgen is prohibited from bundling any of its products with Tepezza or Krystexxa, and from using any product rebate or contract term to exclude or disadvantage products that would compete with those drugs. It also prevents Amgen from buying any competitors to the two Horizon drugs without the FTC's permission. The lawsuit had raised concerns over increased oversight on mergers and acquisitions in a sector that often turns to consolidation to power future growth as patents on older treatments expire. Shares of Seagen Inc (SGEN.O), which is in the process of being acquired by Pfizer (PFE.N), rose 1.5%.

Persons: Robert Galbraith, Lina Khan, Robyn Karnauskus, Khan, Manas Mishra, David Shepardson, Devika Organizations: REUTERS, U.S . Federal Trade Commission, Horizon Therapeutics, FTC, Seagen Inc, Pfizer, Thomson Locations: South San Francisco , California, Amgen, Bengaluru, Washington

REUTERS/Robert Galbraith/File Photo Acquire Licensing RightsORLANDO, Florida, Aug 30 (Reuters) - To buy back, or not to buy back. The highest U.S. interest rates in over 20 years coupled with Wall Street's remarkable resilience has brought an old boardroom dilemma into sharp focus: are share buybacks worth it? Ditto Apple, Chevron, Alphabet and Wells Fargo, which this year have announced buybacks of $90 billion, $75 billion, $70 billion and $30 billion, respectively. Figures from Refinitiv show that S&P 500 companies spent more than $6 trillion on stock buybacks in the decade through 2022. Reuters Image Acquire Licensing Rights(The opinions expressed here are those of the author, a columnist for Reuters.)

Persons: Robert Galbraith, Joe Kleven, Ali Ragih, Nicholas Guest, Kothari, Parth Venkat, Jamie McGeever Organizations: Nvidia, REUTERS, Rights, U.S, Chevron, Mega Tech, Marathon Petroleum, VerityData, Reuters, Apple, Microsoft, Google, Corporate, Cornell University, S.P, Massachusetts Institute of Technology, University of Alabama, Thomson, & ' $ Locations: Santa Clara , California, Rights ORLANDO , Florida, Wells, YCharts, VerityData, U.S, underperformed

☆ Funds punished for owning too few Nvidia shares after stunning 230% rally
▼ + stars: | 2023-08-30 | by ( Lewis Krauskopf | ) www.reuters.com time to read: +5 min

Yet many funds hold less of the stock in their portfolios compared with Nvidia's weight in key equity indexes, making it tougher for them to beat their benchmarks. Among those funds that held a below-average weight in Nvidia, 85% underperformed the index so far this year, Morningstar's data showed. Nvidia's valuation has been a primary reason keeping some investors away, while others are wary of buying in after the stock’s mammoth 230% run this year. Nvidia shares marked a record high closing price on Tuesday, in the wake of a strong earnings report last week. "The stock has had an amazing rally, but it would be totally normal for it to correct 20-25%."

Persons: Robert Galbraith, Refinitiv, ”, Chuck Carlson, Dow, Goldman Sachs, Goldman, Morgan Stanley, Robby Greengold, Jeremy Schwartz, Schwartz, Michael Purves, Purves, ” Purves, Lewis Krauskopf, Ira Iosebashvili, Matthew Lewis Organizations: Nvidia, REUTERS, Nasdaq, Horizon Investment Services, Reuters Graphics Reuters, Big, Microsoft, Dow Jones, Apple, U.S, Mutual, Morningstar, Tallbacken Capital Advisors, Thomson Locations: Santa Clara , California, Big Tech, New York

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