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Or, in other cases, it can open the door to new options for the treatment of obstructive sleep apnea. Treating obesity and addressing sleep apnea Sleep apnea is a serious sleep disorder that results in interrupted breathing, preventing patients — and even their sleeping partners — from getting restful and restorative sleep. Obstructive sleep apnea, the most common form, occurs when muscles in the throat relax and collapse preventing air flow. Before qualifying for the device, patients usually need to have tried treatment with a CPAP machine and an oral device and been unsuccessful. He downgraded Inspire shares to hold at the beginning of the year due to this uncertainty he was anticipating.
Persons: Eli Lilly's Zepbound, Anthony Petrone, Medical's, Eli Lilly, Tim Herbert, Zepbound, Herbert, FactSet, Petrone, UnitedHealth, Jonathan Block Organizations: Novo Nordisk's, Mizuho Securities, CNBC, Systems, Inspire, American Diabetes Association, Drug Administration, National Institutes of Health, BMI Locations: U.S
My wife Pam and I have been married for 37 years. Strictly speaking, it applies only to being married to Pam, but I hope it is sufficiently generalizable to other situations. But date night is the best investment we can make in our marriage. Date night is mutual attention. I wonder how many hours we've spent on date night?
Persons: Malcolm Gladwell, Pam, I've, It's, we've, , He's, I'm, Arnold Palmer Organizations: Service, Business, Google Locations: That's
Philips Respironics has reached a $1.1 billion settlement over claims that people who used their CPAP and other breathing devices were harmed by noxious gasses and flecks of foam that lodged in their airways, sometimes for years. Thousands of people contended in lawsuits that they had been injured by popular Philips DreamStation machines. Philips did not admit any fault in the settlement, including whether the devices caused the injuries, according to a financial report issued Monday. The personal injury settlement follows a $479 million settlement reached in September over economic losses to the patients and medical equipment sales companies that financed replacement devices. Philips also agreed to a consent decree earlier this year that forced the company to halt U.S. sales of new devices until certain conditions are met.
Persons: Philips Respironics, Philips Organizations: Philips
CNN —An implant for obstructive sleep apnea — a serious sleep malady in which breathing stops for 10 seconds to two minutes many times an hour each night — works best in people who are overweight but not severely obese, a new study found. “There’s a huge unmet need of patients that are suffering with obstructive sleep apnea and not able to tolerate CPAP,” Landsness said. nicolesy/iStockphoto/Getty ImagesAbout a third of patients have difficulty using a CPAP and may ultimately abandon the device, Landsness said. Obstructive sleep apnea is also connected to type 2 diabetes, asthma, obesity, kidney disease, chronic obstructive pulmonary disease, thyroid disease and mental illnesses such as depression and anxiety. “As an alternative treatment for sleep apnea, this hypoglossal nerve stimulation surgery could revolutionize some people’s lives,” he said.
Persons: Eric Landsness, St . Louis, ” Landsness, , Kristen Knutson, , Landsness, CPAP, Brandon Peters, Mathews, ” Peters, Raj Dasgupta, Dasgupta, “ I’ve Organizations: CNN, Washington University School of Medicine, Medicare, BMI, Northwestern University’s Feinberg School of Medicine, Virginia Mason Medical Center, Food and Drug Administration, Huntington Health, Mayo Clinic, telltale Locations: St ., Chicago, Seattle, Pasadena , California
Washington CNN —President Joe Biden is fit for duty, his doctor reported Wednesday following the president’s annual physical, in what is expected to be the last update on Biden’s health before November’s election. Dr. Kevin O’Connor said in a memo there are “no new concerns” with the president’s health revealed by this year’s physical. The White House said earlier Wednesday that no cognitive test was administered as O’Connor did not find it necessary. The procedure was “successfully completed” at the White House by a team from Walter Reed, O’Connor said. Reports from the White House physician over the last several decades have consistently described the office-holder as fit to serve.
Persons: Joe Biden, Kevin O’Connor, ” O’Connor, Biden, , SSRS, Karine Jean, Pierre, “ doesn’t, Donald Trump, Jonathan Reiner, ” Reiner, that’s, O’Connor, , Biden’s, ” Biden, Lou Gehrig’s, Robert Hur, I’ve, , seething Biden, “ I’ve, NBC’s, Seth Meyers, ” Wednesday’s Walter Reed, Walter Reed, CNN’s Kevin Liptak, Mira Cheng Organizations: Washington CNN, O’Connor, , State, CNN, Quinnipiac University, White, US Preventive Services, Force, Medical Unit, American Medical Association, National Institutes of Health, White House Locations: Beverly Hills , California, United States
Philips Respironics announced on Monday that it would halt sales of all of its breathing machines in the United States after reaching a settlement with the Food and Drug Administration over continuing problems with the devices. Millions of the company’s ventilators and CPAP machines, used to ease breathing at night, were recalled after reports that they blew bits of foam and potentially toxic gases into consumers’ airways. Under the settlement, Philips said it would have to meet a list of standards in a “multiyear” plan before it could resume business in the United States. The company initially began the recall of millions of devices in June 2021 and paused sales of new sleep therapy machines to the United States, according to Steve Klink, a spokesman for Philips. cited the potential for serious injury or permanent impairment from the potentially cancer-causing chemicals emitted from the devices.
Persons: Philips Respironics, Philips, Steve Klink Organizations: Food and Drug Administration, Philips Locations: United States
WASHINGTON (AP) — The company behind a global recall of sleep apnea machines said Monday it will stop selling the devices in the U.S., under a tentative agreement with regulators that could cost the company nearly $400 million. Philips executives disclosed the tentative agreement during a quarterly earnings update. Under terms of the agreement, Philips would continue servicing recalled machines in the U.S., but would not be able to sell new ones until meeting several corrective actions laid out by the FDA. In November, the agency issued a new warning that the machines can overheat, in rare cases causing fires. Untreated sleep apnea can cause people to stop breathing hundreds of times per night, leading to dangerous drowsiness and increased heart attack risk.
Persons: ” Philips, Roy Jakobs, Philips, , Organizations: WASHINGTON, Manufacturing, Philips, Food and Drug Administration, Department of Justice, FDA . Company, FDA, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: U.S, Pennsylvania, Canada, Australia, Israel, Chile
(Reuters) - The U.S. Food and Drug Administration (FDA) on Thursday classified the recall of certain respiratory masks made by ResMed as most serious as their use could cause major injuries or death. ResMed was recalling some models of its continuous positive airway pressure (CPAP) masks, AirFit and AirTouch, due to possible magnetic interference with certain medical devices and implants which might disrupt their function or position and cause serious harm or death, the FDA said. The FDA said ResMed was recalling these masks to update the labels and add more warnings and information. The California-based medical device maker started the recall process on Nov. 20 and has recalled over 20 million devices in the United States. The health regulator said there has been six reported injuries and no reports of death due to the devices.
Persons: ResMed, Mariam Sunny, Maju Samuel Organizations: Reuters, U.S . Food, Drug Administration, FDA Locations: U.S, California, United States, Bengaluru
US FDA flags new problem with Philips machines, shares fall
  + stars: | 2023-11-28 | by ( ) www.reuters.com   time to read: +2 min
[1/2] Dutch technology company Philips' logo is seen at company headquarters in Amsterdam, Netherlands, January 29, 2019. The new issue identified by the FDA involves a humidifier used in the "DreamStation 2" sleep therapy device. "Philips Respironics is in discussions with the (FDA) regarding the reports," it said. Philips shares were down 6.7% at 18.26 euros by 0833 GMT. The FDA said it had received reports of people facing thermal issues such as fire, smoke, burns, and other signs of overheating while using Philips' DreamStation 2 CPAP machines.
Persons: Eva Plevier, Philips, Toby Sterling, Christy Santhosh, Diana Alvarez, Shailesh Kuber, Jan Harvey Organizations: Philips, REUTERS, U.S . Food, Drug Administration, FDA, ING, Thomson Locations: Dutch, Amsterdam, Netherlands, U.S, Bengaluru, Gdansk
How GLP-1 drugs work Sorting through the facts reveals some likely winners and losers. LLY YTD mountain Eli Lilly shares year to date performance It is still early days for GLP-1 medications. Many have seen the rise of GLP-1 drugs as a threat to the medical device industry. Also, not all patients are able to tolerate GLP-1 drugs, which can cause side effects such as nausea. Among other medtech stocks, Plovanic sees GLP-1 drugs as an "incremental positive" for Dexcom, which makes continuous glucose monitors (CGMs), but an "incremental negative" for insulin pump makers like Insulet.
Persons: Insulet, Medtronic, Dexcom, BAX, NASH, Eli Lilly, Peter Verdult, Lilly, Eli Lilly aren't, Piper Sandler, Wegovy, Yasmeen Rahimi, Robbie Marcus, Marcus, hasn't, Baxter, David Low doesn't, William Plovanic, Craig Wong, Pan, Plovanic, Matt O'Brien, O'Brien, Rippling, Simeon Gutman, Morgan Stanley, Gutman, — CNBC's Michael Bloom Organizations: Novo Nordisk, Baxter International, Baxter, GLP, Citi, Novo, Bank of America, Viking Therapeutics, Pharmaceuticals, Pfizer, Amgen, Companies, Fisher, Reuters, Inspire, Systems, JPMorgan, RBC Capital, Walmart, underperformance Locations: GLP, U.S, DaVita, ResMed
Check out the companies making the biggest moves in premarket trading:Pioneer Natural Resources — The energy stock soared nearly 10% in premarket trading after The Wall Street Journal reported Pioneer was close to reaching a deal to be bought by Exxon Mobil for about $60 billion. Levi Strauss — The denim apparel maker shed 1.3% after cutting its full-year sales forecast. Apellis Pharmaceuticals — Shares of the biopharmaceutical company rose 5.5% after Apellis reported growing sales for its Syfovre drug in August. Aehr Test Systems — Shares fell more than 11% despite Aehr Test Systems reporting an earnings and revenue beat for its first quarter. Frontline — The shipping stock shed 4.8% in premarket trading after Euronav said its second shareholder, Compagnie Maritime Belge, would acquire Frontline's shares in Euronav for $18.43 per share.
Persons: Levi Strauss, Philips —, ResMed, Tesla, Euronav, Macheel, Jesse Pound Organizations: Resources, Street Journal, Exxon Mobil, Exxon, Philips, U.S . Food, Drug Administration, FDA, U.S, Apellis Pharmaceuticals, JPMorgan, Aehr, Systems, Compagnie Maritime Belge Locations: Dutch, U.S, Euronav
Levi Strauss — Shares slid 0.8% after the denim apparel maker cut its full-year sales forecast. Late Thursday, Levi posted fiscal third-quarter revenue that missed expectations, and it cut its full-year sales guidance again. MGM Resorts — The resort and casino operator rose 4.9% after offering an update on a cybersecurity issue experienced last month. Liberty Media Formula One — Shares of the motorsports stock advanced 3.6% following an upgrade to buy from neutral by Citi. Frontdoor — The home repair company's shares climbed 4.4% on the back of a Truist upgrade to buy from hold.
Persons: Tesla, Levi Strauss —, Levi, Aehr, FactSet, Truist, — CNBC's Pia Singh, Yun Li, Michelle Fox, Samantha Subin Organizations: Resources, Street Journal, Exxon Mobil, Exxon, stoke, MGM Resorts, MGM, CNBC, Securities and Exchange Commission, Philips —, U.S . Food, Drug Administration, Philips, FDA, Pharmaceuticals, JPMorgan, Jefferies, Liberty Media, Citi, Las Vegas, UBS, AES Locations: Virginia, U.S
NNN YTD mountain NNN REIT shares have fallen more than 22%. If that vision comes to pass, it could boost apartment operators such as Equity Residential , Avalonbay Communities and Apartment Income REIT , among others. PEAK YTD mountain Healthpeak shares are down 26% since January and hit a 52-week low Tuesday. Healthpeak shares hit a 52-week low on Tuesday, while Welltower shares shed more than 2%. Healthpeak shares are down more than 26% over the same period.
Persons: Jefferies, Jonathan Petersen, Petersen, Simon, Morgan Stanley, — CNBC's Michael Bloom Organizations: Federal Realty Investment Trust, Equity Locations: U.S, Canada
The potential ripple effects of GLP-1 weight loss drugs like Ozempic and Wegovy are far-reaching. These are the stock market's potential winners and losers of the fast-growing weight loss drugs. By contrast, typical weight loss without GLP-1 drugs is mostly driven by a reduction in fat, not muscle. AdvertisementAdvertisementFast-food chains and junk-food companiesMorgan Stanley surveyed 300 patients taking GLP-1 drugs and found that calorie intake dropped 20%-30% on a daily basis. AdvertisementAdvertisementBeer and tobacco companiesAnecdotes from patients taking GLP-1 drugs indicate that the drug helps curb certain addictive behaviors like smoking cigarettes or drinking alcohol.
Persons: Eli Lilly, Catalent, Fisher, McKesson, Baird, Jeff Johnson, Johnson, Morgan Stanley, Kreme, Morgan Stanley's, Phillip Morris Organizations: Service, Street, Novo Nordisk, JPMorgan, Nordisk, Bloomberg, Fitness, Nike, Inspire, Tandem Diabetes Care, KFC, Yum Brands, Anheuser, Busch, Molson Coors Locations: Wall, Silicon, GLP
Fernandez sees a total addressable market of $140 billion to support patients with obesity. He expects there is a potential for GLP-1 drugs to become as common and widely used, much like statins are used to lower cholesterol. Morgan Stanley's Flynn estimates a 30% share of the diabetes market would generate $109 billion on a worldwide basis for GLP-1 drugs. Layer in a 15% to 30% share of the obesity market and that equates to worldwide sales of $97.4 billion to $194.8 billion. Guggenheim's estimates also assume that oral GLP-1 drugs that are currently in development are able to come to market a few years from now.
Persons: Seamus Fernandez, Fernandez, Lilly, Eli Lilly, Morgan Stanley, Terence Flynn, Eli Lilly's Mounjaro, Insulet, Canaccord, William Plovanic, Plovanic, It's, Morgan Stanley's Flynn, Flynn, Novo, Michael Bloom Organizations: Wall, Novo, American Heart Association, Food and Drug Administration, Novo Nordisk, Iqvia, Disease Control Locations: GLP
It is safe to use, but an independent advisory committee to the FDA agreed Tuesday that it is ineffective in pill form. But before then, there are things you can do at home to help relieve your symptoms, he said. Warm compresses, hot showers and hydrationNoses like to be hydrated and warm, Brodner said. But steam from a hot shower or a warm compress placed over your nose can also heat things up nicely. That runny nose will help drain mucus from your sinuses — and hopefully flush out whatever is irritating it, Brodner said.
Persons: , David C, “ You’ll, ” Phenylephrine, Brodner, guaifenesin, Richard J, Harvey, Shanna Miko, you’re, ” Brodner, Stephen Rennard, Larson, Rennard, Organizations: CNN, Food and Drug Administration, FDA, Macquarie University, Epidemic Intelligence, US Centers for Disease Control, CDC, Medicine, University of Nebraska Medical Center Locations: Boynton Beach , Florida, Omaha
New York CNN —CPAP sleep apnea machine maker Philips Respironics agreed to pay at least $479 million in a settlement over alleged health risks from toxic sound reducing foam, lawyers for the plaintiff announced Thursday. The settlement will go toward users who bought or rented the recalled devices and those who incurred out-of-pocket costs or had to reimburse users for those costs, the lawyers said. In 2021, Philips recalled about 10.8 million devices, saying the silicone-based foam they used to reduce sound and vibration can break down and can be breathed in by the user. Philips will pay awards to users for each recalled device, which range from $55.63 to $1,552.25. Philips set aside 575 million euros, or about $615 million, in the first quarter of 2023 to cover the estimated costs, the company said.
Persons: Philips Respironics, , , Philips, ” Philips, They’ll, Claims, Joy Flowers Conti Organizations: New, New York CNN, Philips, Philips Respironics, CNN, FDA, , United States, Court, Western, Western District of Locations: New York, Western District, Western District of Pennsylvania
The economic claims amount is uncapped, which will permit other device users to apply for compensation. This tentative settlement, which is subject to federal court approval, does not address other significant claims in the plaintiffs’ cases involving personal injury or the cost of medical care related to use of the breathing machines. The company has faced a multiyear setback, after beginning recalls in the United States of about five million of its breathing machines, which are intended for people with sleep apnea and other maladies. The lawsuits have claimed that flaking foam and gasses emitted from the machines were linked to health issues including respiratory illnesses, lung cancer and death. The foam was used in the machines to reduce noise and vibration.
Persons: Philips Respironics, Philips Locations: United States
Roku also lifted its third-quarter revenue guidance, saying it now expects revenue to range between $835 million and $875 million, versus prior guidance of $815 million. Along with the workforce reductions, Roku said it plans to consolidate office space and review its content slate to trim expenses. Zscaler posted adjusted earnings of 64 cents per share while analysts polled by LSEG, formerly known as Refinitiv, expected 49 cents. Additionally, the cybersecurity company said earnings and revenue should come in ahead of what analysts anticipate in the current quarter. GitLab — Shares of the technology platform jumped 6.5% in premarket trading following a strong second-quarter report postmarket Tuesday.
Persons: Roku, Zscaler, Needham, GitLab, LSEG, Asana, AeroVironment, Sam Subin, Michelle Fox Theobald, Jesse Pound Organizations: LSEG, Revenue, Dominion Energy, Dominion, UBS, Southwest Airlines —, Southwest, Novo Nordisk — Locations: Hastings, Hudson , New York, Enbridge, Dallas, Danish, Europe
In fact, some 63% of U.S. adults sleep less than the recommended seven to nine hours a night, according to the National Sleep Foundation's Sleep Health Index. There are a myriad of products in the sleep arena — from mattresses and sleep supplements to sleep apnea devices and tech wearables that track sleep. Treating sleep conditions Health conditions can also impact the ability to get a good night's rest, like insomnia and sleep apnea. Obstructive sleep apnea causes breathing to be interrupted during sleep. About half of those surveyed in its obstructive sleep apnea patient survey in July said they had never heard of Inspire.
Persons: Anna Pione, they'll, Seth Basham, Basham, Tempur Sealy, " Basham, It's, Stefano Natella, Natella, it's, Ollie, Seamus Fernandez, Philip's, Philips, Eli Lilly, Eli Lilly's, Guggenheim's Fernandez, Michael Farrell, we've, Fernandez, Novo, wearables, Gene Munster, Jason Ware, Ware, Pione, Michael Bloom Organizations: McKinsey, International Sleep Products, Sealy International, Mattress, Sealy, Centers for Disease Control, Guggenheim, CDC, Unilever, American, of, Care, American Medical Association, Bank of America Securities, Medical Systems, Bank of America, Inspire, Novo Nordisk, Garmin, Apple, Deepwater Asset Management, Apple Watch, Albion Financial, Munster Locations: U.S, dreamland, Mizuho, Novo
Globally, more people searched about sleep this year than ever before, according to data released by Google Trends last week. Hotels and wellness resorts are launching "sleep tourism" programs that go beyond plush bedding and blackout curtains. Source: Zedwell Hotels Trocadero (London) Hotel LtdThe clutter-free aesthetic incorporates natural oak and ambient lighting, and rooms have sound insulation and purified air. Six Senses Laamu, MaldivesSleep-deprived guests can book a sleep wellness program that ranges from three to 10 days at Six Senses Laamu. Carillon Miami Wellness Resort, Miami.
Persons: Cadogan, hypnotherapist Malminder Gill, The Cadogan, Gill, Vicente Mera Organizations: Google, Zedwell, Hotel, Big Apple, Hyatt, Hyatt New, Carillon, Carillon Miami Wellness, Miami Wellness, Sha Wellness Clinic, Sha Wellness Locations: London, Maldives, Switzerland, Fiji, India, Turkey, Thailand, Hyatt , New York, , New York, Hyatt New York, Carillon Miami, Miami, Epsom, Alicante, Spain
June 28 (Reuters) - U.S. President Joe Biden has begun using a continuous positive airway pressure machine, or CPAP, to address a long-standing problem with sleep apnea, White House officials said on Wednesday. He used a CPAP machine last night, which is common for people with that history," White House spokesperson Andrew Bates said. Another White House official said Biden had begun using the CPAP machine in recent weeks to improve his sleep quality. Sleep apnea is a common sleep disorder characterized by brief interruptions of breathing during sleep. In the most common form of sleep apnea, the throat muscles relax, blocking the flow of air into the lungs.
Persons: Joe Biden, Andrew Bates, Biden, Trevor Hunnicutt, Steve Holland, Costas Pitas, Tim Ahmann, Jonathan Oatis Organizations: White, Bloomberg News, Mayo Clinic, Thomson
What is sleep apnea and how is it treated?
  + stars: | 2023-06-28 | by ( Sandee Lamotte | ) edition.cnn.com   time to read: +5 min
The condition is called “obstructive” sleep apnea because unlike central sleep apnea — in which the brain occasionally skips telling the body to breathe — obstructive sleep apnea is due to a blockage of the airways by weak, heavy or relaxed soft tissues. Muscle tone weakens with age, including in the soft palate and neck, making sleep apnea common among people older than 50, experts say. Biden’s getting treatmentIf left untreated, obstructive sleep apnea raises the risk of hypertension, heart disease, type 2 diabetes, depression and even an early death, according to the American Academy of Sleep Medicine. Deep sleep is considered one of the best markers of sleep quality, because a person must typically have relatively uninterrupted sleep to achieve it. Anyone with symptoms of sleep apnea need to be evaluated by a sleep specialist.
Persons: Joe Biden Organizations: CNN, American Academy of Sleep, Mayo Clinic, US Centers for Disease Control, Prevention
President Biden has begun using a CPAP machine in recent weeks to help deal with sleep apnea, a common disorder in which one’s breathing is interrupted as one sleeps, White House officials said Wednesday. When Mr. Biden left the White House on Wednesday morning for a speech in Chicago, he had indentations across both sides of his face from having worn the device, known as a continuous positive airway pressure machine. “Since 2008, the president has disclosed his history with sleep apnea in thorough medical reports,” said Andrew Bates, a White House spokesman. “He used a CPAP machine last night, which is common for people with that history.”CPAP machines are among the most widely used treatments for sleep apnea. The machines deliver a continuous stream of air into masks worn during sleep, helping to keep breathing passages open and ensuring that people receive the oxygen they need.
Persons: Biden, , Andrew Bates, Organizations: White Locations: Chicago
Credit Suisse analyst Trung Huynh has combed through social media and is impressed by the awareness — and demand — for GLP-1 medications such as Eli Lilly 's Mounjaro. Among those observations are reports of other potential benefits that patients taking Mounjaro, or tirzepatide, are seeing. Others taking the drug reported benefits such as a reduction in addiction behaviors such as smoking, drinking, gambling and shopping, among other things. However, this may be a function of patients who are trying to use Mounjaro off-label for obesity, he said. Credit Suisse has an outperform rating on Lilly shares, with a $490 price target, which implies more than 9% upside from where Lilly shares closed Wednesday.
Persons: Trung Huynh, Eli Lilly, Huynh, Mounjaro, agonism, Lilly hasn't, semaglutide —, Lilly, , Michael Bloom Organizations: Credit Suisse, Food and Drug Administration, Novo Nordisk
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