Google challenged the directive in the Supreme Court saying it would hurt consumers and also its business, warning the growth of the Android ecosystem could stall.
A three-judge bench of the Supreme Court, which included the chief justice of India, extended the implementation date of CCI's directives by a week beyond Jan. 19, but declined to block the ruling despite Google's repeated requests.
Google licenses its Android system to smartphone makers, but critics say it imposes restrictions such as mandatory pre-installation of its own apps that are anti-competitive.
Google also says in its India filings that "no other jurisdiction has ever asked for such far-reaching changes".
"We have not cut, copy and paste," N Venkataraman, a government lawyer representing the Competition Commission of India (CCI), told the top court.