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LONDON, April 21 (Reuters) - African countries are lining up to approve a new vaccine for malaria, with 20 million doses available for them to buy this year, the shot’s manufacturer told Reuters. African countries that do not have extensive resources for drug regulation have previously relied on the U.N. agency to initially review new medicines. "We expect many more countries to come through," Mary Hamel, the WHO's malaria vaccine implementation head, told the expert meeting on Tuesday. “We are committed to making the R21 vaccine available to people who need it most,” Poonawalla said. FUNDING DOUBTSThe moves are a further sign that African countries want to exert their own pharmaceutical oversight after COVID-19 exposed inequity in vaccine supply.
The University of Oxford Jenner Institute, which developed the vaccine, estimates that malaria kills around 800,000 people per annum. These casualties occur predominantly in sub-Saharan Africa, where one in five childhood deaths is associated with the disease. The WHO assessed that 241 million clinical cases of malaria occurred in 2020, resulting in 627,000 deaths, mostly among children in Africa. A health worker vaccinates a child against malaria in Ndhiwa, Homabay County, western Kenya on September 13, 2019 during the launch of malaria vaccine in Kenya. Brian Ongoro | AFP | Getty ImagesIn 2021, the WHO signed off on GSK's RTS,S malaria vaccine for rollout across sub-Saharan Africa, following pilot programs in Ghana, Kenya and Malawi, which tracked 800,000 children since 2019.
Oxford scientist Adrian Hill said Ghana's drug regulator has approved the vaccine domestically for the age group at highest risk of death from malaria - children aged 5 months to 36 months. Oxford has a deal with Serum Institute of India to produce up to 200 million doses of the vaccine - known as R21 - annually. "This shows how close the world is to having a second approved vaccine to fight malaria," he said. MEETING THE NEEDThe first malaria vaccine, Mosquirix from British drugmaker GSK (GSK.L), was endorsed by the WHO last year after decades of work. Since it began in 2019, 1.2 million children across the three countries have received at least one dose of the Mosquirix vaccine.
At the upcoming Mobile World Congress event in Barcelona, collaboration and convergence will be priorities. MWC is a 'Digital World Congress' that will see more worldwide digital innovation from the UK and across the world." Attocore, recently awarded a grant for accelerating Radio Access Network (RAN) intelligence, sits alongside mobile giants Ericsson and Samsung in advancing the security of UK mobile networks. With 5G networks, an estimated £173 billion of incremental UK GDP will be added to the UK economy by 2030. MWC and scaling UK technologyMobile World Congress is also a great opportunity for big ideas to reach an even bigger audience.
Testat pe 450 de copii din Burkina Faso, vaccinul s-a dovedit a fi sigur și a prezentat o eficacitate ridicată la 12 luni de la data administrării. Cel mai eficient vaccin pentru malarie existent a prezentat o eficacitate de doar 55% în testele efectuate pe copii africani. Vaccinul a arătat o eficacitate de 77% în grupul cu doze mari și 71% în grupul cu doze mici. Halidou Tinto, profesor de Parazitologie și principalul cercetător implicat în teste de la unitatea de cercetare din Nanoro (Burkina Faso), a spus că rezultatele sunt "foarte interesante" și arată "o eficacitate fără precedent". Malaria este una dintre principalele cauze ale mortalității la copii în Africa și profesorul Charlemagne Ouédraogo, ministrul Sănătății din Burkina Faso, a spus că noile date arată că un nou vaccin pentru malarie ar putea aprobat "în anii următori".
Persons: Adrian Hill, Jenner, Hill, Halidou, Charlemagne Organizations: Organizația Mondială a Sănătății ( OMS, Universitatea Oxford, Organizației Mondiale a Sănătății, Charlemagne Ouédraogo, Sănătății Locations: Burkina Faso, Oxford, Nanoro, SUA, India, Africa
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