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☆ At 80, Steve Miller Calls Himself a ‘Late Bloomer’
▼ + stars: | 2023-11-17 | by ( Alan Paul | ) www.wsj.com time to read: +1 min

Steve Miller, 1970s rock icon, strolled out onto an elegant Jazz at Lincoln Center stage last week, sat down on a stool and picked up a custom double-necked acoustic guitar. Smiling widely, he told the sold-out crowd that he was going to start with “a different version” of a song they’d all know. The two versions, almost a half century apart, were instantly connected by the familiar timbre of Miller’s voice. At this show, his seventh annual two-night celebration of the blues, Miller performed only two of his own songs, otherwise concentrating on the music of his blues influences and mentors. “He’s just going to take this music we love into the future,” Miller said backstage in an interview a few days earlier.

Persons: Steve Miller, Miller, Christone, ” Ingram, “ He’s, ” Miller, “, ” Organizations: Lincoln Center, Jet

☆ Murky road ahead for Duchenne gene therapy as confirmatory trial misses main goal
▼ + stars: | 2023-10-31 | by ( Meg Tirrell | ) edition.cnn.com time to read: +4 min

Sarepta gave the one-time drug a price tag of $3.2 million, making it the second most-expensive medicine in the world. DMD affects one in 3,500 to 5,000 newborns, mostly boys because of the way it’s inherited, according to Johns Hopkins Medicine. The primary goal of the confirmatory trial was improvement on a measure known as the North Star Ambulatory Assessment, a scale of how well kids can stand, walk and perform other movements. The difference wasn’t statistically significant, meaning technically the study failed to meet its main goal. The company said no new safety issues emerged in the trial, which it called EMBARK.

Persons: Doug Ingram, ” Ingram, Sarepta, “, Dr, Sanjay Gupta, Ingram, ” Organizations: CNN, US Food and Drug Administration, Sarepta Therapeutics, FDA, Johns Hopkins Medicine, North Star, CNN Health

The program, called the U.S. President’s Emergency Plan for AIDS Relief Program, or PEPFAR, started in 2003 by President George W. Bush. Congress missed the Sept. 30 deadline to renew funding for PEPFAR before it expired. The policy had not been included as a part of PEPFAR funding until 2017, when the Trump administration expanded the policy to include it as a part of the program. Advocates for PEPFAR contend the program does not directly or indirectly fund abortion services. For some countries, the health benefits of the PEPFAR program go beyond its mission of reducing the spread of AIDS.

Persons: George W, Joe Biden, PEPFAR, “, ”, Chris Smith, Biden, Ronald Reagan, Trump, Bush, George Ingram, Matthew Miller, ” Miller, reauthorization, Ingram, ” Ingram, Carlos del Rio Organizations: U.S, President’s, AIDS Relief, U.S . State Department, PEPFAR, Congress, House Republicans, Biden Administration, House Global Health, Senate, Senators, Republicans, Center for Sustainable Development, Brookings Institute, Kaiser Family Foundation, Program, Emory University School of Medicine, State, Committee, Infectious Diseases Society of America Locations: U.S, New Jersey, Mexico, Washington, Africa, China, Russia

☆ Buckle Your (DeLorean) Seatbelt: ‘Back to the Future’ Lands on Broadway
▼ + stars: | 2023-07-24 | by ( Dave Itzkoff | More About Dave Itzkoff | ) www.nytimes.com time to read: +1 min

Gale’s inspiration for “Back to the Future” came in 1980 after seeing a photo of his father as a teenager in an old high-school yearbook, and he has become a passionate custodian of the franchise. That role dates back to at least 1989, the year a notorious “Back to the Future” Nintendo game was released. “One of the worst games ever,” he said. “The creative differences and the chemistry just didn’t work,” Ingram said. (Through a press representative, Lloyd confirmed that his departure was a mutual decision over creative differences but declined to comment further.)

Persons: ”, “, Zemeckis, Leslie, Alan Silvestri, Glen Ballard, Silvestri, ” Gale, let’s, Gale, Colin Ingram, Ballard, Jamie Lloyd, ” Ingram, Lloyd Organizations: Nintendo, Polar, Broadway Locations: British

CNN —Leslie Jordan, beloved comedian and actor known for his work on “Will and Grace,” has died, his agent announced. “The world is definitely a much darker place today without the love and light of Leslie Jordan. Sources told the Los Angeles Times Jordan was involved in a car accident on Monday morning in Hollywood. Megan Mullally and Leslie Jordan in "Will and Grace." Jordan talked to CNN’s Anderson Cooper about his past substance abuse and being sober for more than 20 years.

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